Phenotropil (active ingredient - phenylpiracetam) - a relatively new drug, a stimulant, has on the complex effect. Initially he considered only fenotropil neuroprotective drugs and antidepressants, but the effect of the drug on the human body was far more versatile. Due fonturatsetama neuromodulator activity, the active ingredient Phenotropil today this drug can rank as psychoactive, anxiolytic, antidepressant, nootropic drugs. In fact fenotropil is the founder of a totally new class of drugs - the so-called neuromodulators of the central type of action.
Phenylpiracetam active ingredient Phenotropil - nootropic agent piracetam one of the derivatives, the ancestor class nootropics, to this day is used for the treatment of certain neurological and psychiatric disorders. Phenotropil shown in various central nervous system disorders, depression, schizophrenia. To have a greater value, however, stimulant properties of the drug: fenotropil increases stress, it stimulates brain activity, helps with fatigue, improves physical and mental performance. And finally, one of the major advantages of Phenotropil - no risk of addiction even at course of treatment.
Safe stimulant or doping?
Fenilpiratsetam, Phenotropil active ingredient, in the EU and the United States included in the list of banned doping substances, regularly supplemented by WADA - the independent organization set up with the support of the International Olympic Committee (IOC)
. Fenilpiratsetam considered doping forbidden to receive all Olympic sports
. Because of the ban on fenilpiratsetam over the past few years we have suffered some athletes: for example, in February 2006, the Russian biathlete, winner of the silver medal of the Olympic Games Olga Pyleva was disqualified after the Anti-Doping Commission of positive results of a blood test on doping substances
. Pyleva itself claimed that Carphedon (fenilpiratsetam) was part of the drugs recommended by her personal physician
. In 2008, the same sanctions have been applied against the Russian sportsman Roman Usov, which banned to take part in the Beijing Olympics, again due fenilpiratsetama
.
Potential complications
The stimulating effect of any nootropic drug rarely goes to the body without any consequences. Permanent artificial stimulation of receptors in the composition of chemical compounds such stimulant drugs may lead to depletion of a different nature - a nervous, emotional exhaustion. Perhaps something similar effect is observed during chronic administration of drugs, antidepressants, also affecting the receptors in the brain - not for nothing at the end of the course of treatment is required to reduce the dosage gradually to avoid withdrawal symptoms. Increased irritability
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, Sleep disorders and insomnia, fatigue, lethargy, inability to experience strong emotions or, on the contrary, mood swings
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, Heightened emotionality - just a few of the potential impact of long-term use Phenotropil provided there is no need in this preparation.
Do not forget about the contraindications: pregnant women, breastfeeding women, children under eighteen years of age can not take fenotropil. In addition, it fenotropil not recommended if you are hypersensitive to the drug - there are cases where even at the first reception, the standard dosage fenotropil causes abnormal side effects such as cramps, nosebleeds, dizziness and so on. In such cases, of course, of the drug should be avoided. Phenotropil released only by prescription and, respectively, for receiving the drug should be a good reason.
Mechanism of action
Phenotropil - domestic neuroprotective drugs of the last generation, which has a strong psychoactive effect and has no analogues. It was developed by Russian scientists as a means of enhancing physical and mental performance of astronauts during space flight. High efficiency and safety of the drug and allow its use for the treatment of patients.
The mechanism of action of Phenotropil is that it has a positive effect on metabolic processes (including the carbohydrate metabolism resulting in a higher amount of energy) and the circulation of the brain, improves blood circulation in the brain, supplying it with oxygen, including regions of the brain modified after a stroke. Increases of neurotransmitters - substances with which excitation is transmitted to the brain cells.
Fenotropilom caused by biochemical processes in the brain allows him to exert an active influence on the processes of memory, concentration and mental activity. It facilitates the learning process, increases the speed of information transfer in the brain, brain tissue increases resistance to oxygen deficiency and toxic effects, possesses anticonvulsant effect, regulates the processes of excitation and inhibition in the central nervous system, improves mood, visual acuity.
Furthermore, since fenotropil having an active influence on metabolic processes in the organism, when its exchange application marked decrease in edema and weight reduction. In applying Phenotropil increases the body's resistance to stress and fatigue.
Despite the fact that the drug has a pronounced effect on the central nervous system, it has almost no side effects and contraindications for use. Before the drug in the form of a course does not develop drug dependence and addictive, it is not required to increase the dosage to achieve the desired effect.
Phenotropil rapidly absorbed in the gastrointestinal tract, the maximum concentration in blood is achieved in one hour. A few hours later the drug is excreted unchanged in the urine, faeces and sweat.
Indications for use
Phenotropil has wide indications for use:
- central nervous system diseases of various origins, especially those related to cardiovascular diseases and disorders of metabolic processes in the brain, which are accompanied by impaired mental activity, memory and decreased motor activity;
- neuroses (nervous system disorders, developing in response to stress), which are accompanied by lethargy, increased exhaustion, decreased mental and motor activity, in violation of attention, memory impairment;
- learning disabilities;
- mood disorders (depression);
- disorders of the brain, associated with changes in brain structures (for example, after an injury) that appear impaired memory, thinking abilities and willpower;
- motor disorders and mental activity in schizophrenia;
- diseases accompanied by convulsions;
- obesity is not associated with endocrine diseases;
- chronic alcoholism with severe mental disorders.
In addition, fenotropil used to prevent oxygen deficiency, increase resistance to various mental influences, in extreme conditions to prevent state of exhaustion.
Contraindications Phenotropil and side effects when taking
Phenotropil contraindicated if you are hypersensitive, and the presence of allergic reactions when taking the other drugs in this group. Do not appoint fenotropil pregnant women, breast-feeding
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baby and children have been in respect of these groups of patients, clinical studies have not been conducted.
With caution it is administered to patients with impaired liver and kidney function, severe hypertension, atherosclerosis. Since fenotropil activates mental processes, it must be very carefully appoint repetitive vegetative-vascular crises, accompanied by fear, anxiety, severe mental disorders (psychosis), accompanied by mental and motor agitation, since it is possible aggravation of anxiety and panic.
Before the drug in the second half of the day may be sleep disturbances
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. In some cases it may be motor and mental excitement, facial redness, increased blood pressure.
When used properly (by a doctor) fenotropil has excellent therapeutic and preventive effects on the central nervous system.
Galina Romanenko