Interesting facts

Aktovegin - drug allegedly used by athletes as a performance-enhancing drugs to improve performance, has recently appeared in the epicenter of the scandal. Canadian doctor who treated Tiger Woods became a defendant in an investigation of American life doping control, and found that Canadian athletes are allowed to take aktovegin and a number of other drugs, which can be classified as doping.

What aktovegin?

Aktovegin - drug obtained from the blood of calves by ultrafiltration, whereby the active therefore physiological effects on the body aktovegin virtually no contraindications. As stated on the website of the manufacturer, an Austrian pharmaceutical company, as a raw material is taken the blood of calves under the age of eight months.

But the story begins long aktovegina until 1996, when he was put into production. Studies were conducted on its development since the mid-seventies.

Application aktovegina medicine

Aktovegin improves blood circulation, so it is widely used for various violations by the brain, such as after a stroke Stroke - a serious brain injury When deteriorating process of glucose absorption Glucose: The energy source   its assimilation of brain cells. The drug is also prescribed to patients with diabetes Diabetes - threatening and incurable disease Including diabetic patients with cardiovascular disorders, such as trophic ulcers Trophic ulcer - can you handle it? As it has insulin-like activity.

What are the benefits for athletes aktovegina?

According to the research, aktovegin has insulin-like effect, ie it stimulates the transport and accumulation of glucose and oxygen, increasing their intracellular recycling.

This is good news for athletes, as improved oxygen supply to muscle tissue increases the effectiveness of training and sports in general.

Opinion of the International Olympic Committee on aktovegin

In December 2000, the International Olympic Committee made aktovegin the list of banned drugs, mainly because of the blatant abuse of athletes-cyclists. During the Tour de France in 2000 aktovegin at the center of a scandal when a team of Lance Armstrong accused of doping. True, the team persistently denied all charges.

But in 2001 the International Olympic Committee ruled aktovegin from the list of banned drugs because of the lack of information about the drug.

How widely used aktovegin?

Not all athletes take aktovegin. Many similar preparations have a more dramatic effect.

Aktovegin discharged in the form of dragees in multiples of 100 pieces, a solution for injection in ampoules of infusion solution 10% and 20% saline, 20% gel, 5% cream and ointment 5%. Store this medication in a dry place at temperatures no higher than 8 ° C. The main markets spread aktovegina: Europe, China and the former Soviet Union.

Mechanism of action

Andipal refers to a group of drugs that have analgesic and relieves spasms of smooth muscles of internal organs of action. The drug combination, one tablet contains 250 mg of sodium metamizol 20 mg bendazol, 20 mg papaverine Papaverine - for pain caused by spasms of smooth muscles   hydrochloride and 20 mg of pentobarbital.

Metamizole or analginum has a strong analgesic, anti-inflammatory and antipyretic activity. As is well soluble and is easily absorbed drug, it is particularly suitable for use in cases when it is necessary to quickly create a high blood concentration of the drug.

Bendazol (Dibazolum) has vasodilatory, relieves spasm (contraction) of smooth muscles of internal organs and lowers blood pressure Blood pressure - dangerous if his swing?   action, as well as a stimulating effect on the function of the spinal cord. In addition, Dibazolum stimulates the body's defenses (immune system). Apply it with spasms of smooth muscles of the gastrointestinal tract and blood vessels, as well as in the treatment of nervous diseases, mainly residual effects of peripheral nerve lesions (eg facial nerve). Dibazol is also used as a mild immunostimulatory agent, lowers the tone and causes dilation of the blood vessels of the brain, but its effect is very short-lived.

Papaverine hidrohlorid - is an alkaloid found in opium, has a good antispasmodic (relieves spasms of smooth muscles of internal organs and blood vessels) effect. In high doses, reduces the excitability of cardiac muscle conductivity and slows intracardiac.

Phenobarbital - sedative and antiepileptic agent. In small doses, it has a calming effect, and in combination with other drugs (antispasmodics and analgesics) is used in the treatment of internal diseases involving smooth muscle spasm.

The total effect of the combined drug andipal - analgesic, antispasmodic and vasodilator - all this is due to the properties of its components.

Who can apply andipal

Admission andipal shown mainly patients suffering from chronic diseases of the gastrointestinal tract, accompanied by muscle spasms and pain of internal organs (gastritis, cholecystitis, colitis, pancreatitis).

It will andipal and headaches - comes off a spasm of blood vessels that carry blood to the brain. But the headache of migraine I have a migraine. What to do?   this drug may strengthen as migraine headache from a sharp expansion of blood vessels and expand them further andipal. In combination with other drugs to lower blood pressure, help with severe headaches during a hypertensive crisis Hypertensive crisis: how to protect themselves from the consequences of .

Assuming it is possible to 1-2 tablets three times a day for no more than 5-7 consecutive days.

Contraindications andipal

Contraindications andipal are:

• severe liver disease and kidney with a violation of their functions;
• lack of glucose-6-phosphate dehydrogenase (anemia with increased blood clotting hereditary nature) and other blood diseases (analginum can affect the formation of blood);
• violation of the excitability of heart rate (heart block);
• muscle weakness (myasthenia gravis);
• porphyria (an inherited disorder of pigment metabolism);
• pregnancy and breastfeeding;
• hypersensitivity to the drug.

Side effects andipal

Andipal has a combined structure, and therefore side effects with him a few:

• from the gastrointestinal tract: nausea, constipation;
• from the blood: long-term use of the drug is possible inhibitory effect on the blood due to the presence of dipyrone (reduced white blood cell count and platelets, that is, reduced safety and rolling svoysva blood);
• the central nervous system: phenobarbital, present in the composition of the drug, can have a depressing effect on the central nervous system, it is sometimes possible movement disorders in elderly and debilitated patients - low mood (depression);
• allergic reactions (up to anaphylactic shock).

Andipal may also increase the effects of drugs that have a depressant effect on the central nervous system, including ethyl alcohol, so it is not necessary to combine the intake of alcohol.