- Chemotherapy - it always falls the hair?
- Medications
Drugs used for chemotherapy
All the funds used for the drug treatment of malignant tumors, divided into two groups: hormonal drugs and anticancer drugs actually synthetic and natural origin.
Hormonal drugs are mainly used to treat tumors that retain the ability to respond to the initial tissue hormones that normally regulate their growth. This so-called hormone-dependent tumors, which are cancer of the prostate
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, mammary cancer
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, Uterine cancer, thyroid cancer
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. Close to hormonal anti-estrogens - drugs that block the action of female sex hormones estrogen, contributing to the growth of hormone-dependent tumors.
Action actually antitumor drugs is associated with inhibition of metabolic processes in tumor cells that suspends their proliferation (cytostatic effect). Simultaneously, they usually have an effect on the metabolism (first exchange of nucleic acids), bone marrow, gastrointestinal tract and other organs and tissues, and what their associated side effects.
The action of many anticancer agents that have a suppressive effect on metabolic processes in tumor cells is based on interactions with enzymes (protein substances that accelerate chemical processes) that are involved in the formation of DNA and RNA tumor cells. Antitumor action of herbal medicines due to the suppression of tumor cell division (mitosis).
Currently, an intensive search for anticancer agents that can selectively destroy the substance in which tumor cells are particularly needed.
Features of influence on tumor chemotherapy drugs
Tumor cells, as well as healthy cells and tissues, multiply by division, which consists of a series of successive phases. Actively dividing cells are more sensitive to the chemotherapeutic effects, however, such fast-growing tumors as leukemia, lymphosarcoma, and so forth, respond well to drug treatment. And since there are also healthy tissue, are prone to rapid proliferation (e.g., bone marrow), they are also adversely affected during the treatment period. Therefore, treatment of fast-growing tumors are trying to carry out short-term intensive courses (the tumor cells grow still more rapidly than normal cells) with breaks during which restores the normal tissues.
In contrast, tumor cells are propagated slowly (e.g., lung cancer) or temporarily stopped its growth to the drug effects are less sensitive. Therefore, to treat them apply more prolonged courses of chemotherapy with long intervals between re-treatment.
The results of the application of chemotherapy, even with highly sensitive to her tumors are directly dependent on the number of tumor cells: the fewer, the better the treatment. Therefore, chemotherapy often is the second stage of treatment after surgical removal of tumors or radiotherapy.
Complications that may occur during chemotherapy
Antineoplastic and damage healthy tissue, mainly their negative impact affects growing tissues bone marrow, gastrointestinal tract and hair follicles.
Negative effects of chemotherapy on the bone marrow is that inhibited the production of leukocytes (and hence suffers immunity
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and the patient becomes vulnerable to any infection), and platelets (platelets responsible for blood clotting and a tendency of decrease in bleeding). To a lesser extent red blood cells suffer - erythrocytes.
Equally chemotherapy have a negative impact on other fast growing cells - cells of the gastrointestinal tract and liver. It causes nausea, vomiting, diarrhea, inflammation of the mucous membrane of the mouth (stomatitis), and other phenomena that are generally poorly tolerated by patients.
The skin in the treatment of chemotherapy may appear itchy rash of various kinds, and in the future - skin discoloration, infection joining (pustular rashes). Suffer and skin appendages, particularly the hair follicles, which is why hair loss occurs, which eventually passes: after about weather hair growth is restored.
Chemotherapy - is an effective but hard-tolerated treatment for patients.
Galina Romanenko