Impaza and mechanism of action

Impaza (international name - Antibodies to endothelial NO-synthase) - a monocomponent homeopathic drug that restores the impaired erectile function by increasing the amount of NO-synthase, which is the source of nitric oxide .  Impaza is the first and only drug having such a mechanism of action .  It is an ultralow doses of antibodies to the enzyme endothelial NO-synthase, which despite the introduction of the opposite mechanism of action (antibodies should be glued to the antigen-sinteazoy and output it from the body) causes an increase in number of endothelial NO-synthase .  That is, when administration of the drug is increased (restored) ability of the endothelium to produce NO, which means that Impaza helps to restore erectile function .  It was found that both single and at course introduction Impaza in the tissue of the corpora cavernosa increases the content of NO derivatives .

In this case, the following mechanism: the human body has a system of its own antibodies to virtually all substances circulating in it's own antibodies to endothelial NO-synthase regulate its level by suppressing it. The introduction of ultra-low doses outside the same antibodies (Impaza) induces the appearance of antibodies to them and to their own antibodies Antibodies - "soldiers' immunity . Their number decreases, the negative impact on the NO-synthase is inhibited, and its quantity increases, which starts in response to sexual stimulation cascade of biochemical mechanisms that lead to an erection Erection - what hinders and what helps a man to be a man .

Due to the positive effects on the central mechanisms regulating erection drug increases libido (sex drive) and satisfaction with sexual intercourse. Long-term use of the drug enhances testosterone Five myths about testosterone   (male sex hormone) in the blood serum. Normalizes autonomic disorders of menopause in men (weakness, fatigue, decreased physical activity, decreased libido, etc.).

Indications

Indications for use Impaza are:

• erectile dysfunction of various origins;
• autonomic disorders of menopause in men (weakness, fatigue, decreased physical activity, decreased libido, etc.).

Contraindications

Contraindications Impaza is just a heightened sensitivity to the drug. Other contraindications have been identified.

Side effects when using Impaza of indications and at the recommended doses were not revealed. Information about the overdoses and no.

As used

To stimulate the erection drug is taken on the day of the alleged sexual intercourse twice: one tablet 2-4 hours before sexual intercourse, the second - an hour before sexual intercourse. The most stable effect seen with the drug is not more than 2-3 times per week. Tablets are taken 15-20 minutes before meals and kept in the mouth until it is completely dissolved.

To stabilize the sexual potency recommended cure duration of 12 weeks, during which the drug is taken in a day one tablet, preferably in the evening. The course can be repeated after 4-6 months.

Impaza fairly safe drug, but to make it better for its intended purpose and under the guidance of a doctor, after a thorough examination.

Are there indications for circumcision

First of all, the removal of the foreskin may be purely hygienic procedure, which prevents the development of urinary tract infection. As a result of the operation of circumcision the glans penis is always in the open and not smegma accumulates in the prepuce, which reduces the risk of bacterial and viral infections.

But there are absolute indications for circumcision, they are phimosis Phimosis - whether to go to extremes?   and damage to the foreskin. Phimosis - a different degree of narrowing of the foreskin. This narrowing can be easy (the foreskin is hardly bares a head during erection Erection - what hinders and what helps a man to be a man It is easy to open it in a calm state of the penis) and very heavy (urine during urination first accumulates in the prepuce, and then drops excreted). Phimosis is dangerous because it can cause inflammation of the glans penis and foreskin (balanoposthitis) and infringement of the foreskin glans penis (paraphimosis), resulting in a violation of the blood flow in it and necrosis (death of tissue of the glans penis).

Damage to the foreskin as an absolute indication for circumcision. They can cause any trauma, an open wound or a strong bruise foreskin. When wound healing the resulting scar can cause narrowing of the foreskin, so it is better to remove.

Circumcision is often performed at the premature ejaculation and insufficient duration of sexual intercourse as a result of this operation decreases the sensitivity of the penis.

How do circumcision

Operation circumcision is usually performed under local anesthesia. Then special clamps pulled foreskin (if it is adherent to the glans penis, then it is separated from the probe), and the circle is excised with scissors (the blood vessels at this point superimposed clips, and then they are tied resorbable thread). On the wound sterile dressing is applied.

Circumcision may be partial (half-head closes the remaining foreskin in the quiescent state of the penis) or complete (head of the penis is always open). This frenulum (longitudinal narrow crease that runs from the external opening of the urethra to the coronal sulcus), circumcision is not affected, since by her to the head of the penis are small blood and lymphatic vessels and nerve branches. Typically, the operation lasts about an hour, and after 10-14 days, a person can live a full life, including sex.

But sometimes a person may have a short frenulum of the penis, which can tear during intercourse, then become inflamed and then decreases its elasticity. In such cases, along with circumcision performed plastic surgery frenulum of the penis. Circumcision surgery and plastic bridle can be performed simultaneously.

The bandage is removed after the surgery within two or three days. Stitches usually resolve within a few weeks, it is not necessary to remove them.

Complications after circumcision

Circumcision should be performed only in hospitals surgeon-urologist, while complications are extremely rare. Usually it is a hematoma (accumulation of blood under the skin) and infection of the surgical wound. A hematoma may occur due to inadequate ligation of small blood vessels, this complication is eliminated quickly.

Infection of the surgical wound is not uncommon, due to the anatomical features of the operated area: bandage soaked in blood, lymph and urine, and the environment are nutrients for pathogens. But also with this complication in our time easy to handle - appointed antibiotics Antibiotics - whether they will help you in the foreseeable future? .

Circumcision - medical and hygienic operation, proven for centuries. Therefore, if you have evidence for such an operation and the urologist advises her to spend, it makes sense to listen to his advice.

  Galina Romanenko