Ampicillin is not contraindicated during pregnancy, but to appoint him standing with caution, as the impact on the body of the pregnant women of different drugs studied enough. Special care should be prescribed the drug in the first trimester of pregnancy.

First trimester of pregnancy

Ampicillin in the first trimester of pregnancy (the first twelve weeks), like any other drug should be used with great caution and only in the event that his appointment is required for health reasons.

Such an attitude to drugs in the first trimester of pregnancy is necessary, because in this period is laying the tissues and organs of the embryo. Any substance that is able to interfere with the metabolic processes may cause a violation of a bookmark that will result in developmental abnormalities (malformations) in a newborn. Ampicillin in this respect is no better and no worse than any other substance.

However, if the condition of the woman requires antibiotic, they are assigned based on indications, contraindications and side effects of these drugs. It allowed for the use of antibiotics during pregnancy Antibiotics - whether they will help you in the foreseeable future?   It refers ampicillin.

The second trimester of pregnancy

In the second trimester of pregnancy (thirteen to twenty-four weeks) the state of health of the pregnant woman is improving, but the immune system it is reduced. Therefore, it is possible the development of infectious and inflammatory diseases. Most of these diseases develop in the nose, throat and upper respiratory tract. In this disease in most cases begins with the viral infection and immunity have been reduced in pregnant women are often joined to viral bacterial infections. When to stop such an infection home remedies can not, then appointed antibiotics, including ampicillin. Ampicillin and inflammatory processes in the kidneys and urinary tract - cystitis and pyelonephritis, which often develops in pregnant women.

Because of its side effects trouble can deliver mostly violations of the gastrointestinal tract. They may take the form of dysbiosis, digestive disorders accompanied by symptoms - bloating, alternating constipation and diarrhea, pain during bowel. During long-term treatment may "earn" and intestinal inflammation - colitis. Ampicillin may have adverse effects on the liver, which is manifested in the transient violations of its functions. Sometimes such violations appear icteric staining of the skin.

Furthermore, ampicillin has the side effect of reducing the number of leukocytes in the blood, including the complete or almost complete disappearance of the granular leukocytes (agranulocytosis). This is a dangerous condition for a pregnant woman, because it speaks of the marked decrease in immunity Immunity - types and characteristics in children in adults . Immunosuppression during pregnancy often leads to the development of genital candidiasis Candidiasis genitals: possible severe complications   - Yeast, from which then so hard to get rid of. Therefore, to use ampicillin alone a pregnant woman can not even be in this relatively quiet period.

The third trimester of pregnancy

In the third trimester of pregnancy (with the twenty-fifth week before delivery) threat to the health of women and the fetus from the medication increase again. Receiving ampicillin except discomfort from the gastrointestinal tract and the reduction of immunity, and creates another threat of bleeding as a side effect of reducing blood coagulation and reduce blood platelet count Platelets - what they are for the body? . And before birth is quite useless.

There is also the threat of anemia - Ampicillin suppresses the formation of red blood cells, and their number in the blood decreases. And it was the red blood cells, which contain hemoglobin, carried to the tissues of mother and fetus oxygen so when anemia (especially if it is expressed much) is almost always present signs of feto-placental insufficiency, which affects mainly the central nervous system of the fetus.

Together, the side effects of ampicillin can create significant problems in the third trimester of pregnancy. However, the correct assignment of the drug brings benefits - saves a pregnant woman from infection and prevents its penetration to the fetus, that is, the development of intrauterine infection.

Galina Romanenko

Pregnancy itself - quite a difficult period in the life of a woman, so a cold or allergy can significantly worsen the health of the expectant mother. During pregnancy, regularly taking any medicines, except in special cases, is not recommended - even if it is antihistamines, which are considered the safest medications to combat the symptoms of allergic diseases.

Cetirizine

Cetirizine (brand name Zyrtec) - an antihistamine prescription. Cetirizine, according to the official classification of the safety of drugs in pregnancy, is a category B - which means that, theoretically, it is safe for both mother and the developing fetus. In cetirizine, unlike the first generation antihistamines, no pronounced sedative effect, so it is suitable for the treatment of allergy symptoms even in pregnant women. Among the possible side effects of cetirizine include dizziness, dry mouth, sore throat, cough, nausea, constipation and headache.

Chlorpheniramine

Chlorpheniramine - antihistamine, available on prescription and is sold under many different trade names. Like cetirizine, chlorpheniramine included in category B and a potentially safe for pregnant women. The main side effects of chlorpheniramine - drowsiness, dry mouth, dizziness, mild Dizziness - if the ground is slipping from under his feet   and blurred vision, abdominal pain Abdominal pain: Types and Symptoms , Constipation, decreased concentration and attention.

Fexofenadine

Fexofenadine (brand name Allegra), as well as other representatives of the group of antihistamines, available only by prescription, and according to the basic classification, included in the category C - a potential threat to the health of the developing fetus fexofenadine unknown. It is for this reason that fexofenadine during pregnancy are often not recommended to take. The main side effects of the drug - nausea, diarrhea, stomach upset, cramping, similar to menstrual pain, back pain and muscle aches.

Loratadine

Loratadine - an antihistamine, which is available in some pharmacies without a prescription (one of the most common trade names of loratadine - Claritin). Loratadine belongs to the category B - the antihistamine is considered one of the safest for pregnant women and the least likely cause drowsiness. Possible side effects of loratadine - dizziness, dry mouth, headache Headache: Causes and Complications , Increased nervousness, abdominal pain, diarrhea, nosebleeds, skin rashes.

Diphenhydramine

Diphenhydramine (brand name Benadryl) is sold without a prescription, not only in pharmacies, but also in some superkarmetah. This drug belongs to a category B, it is potentially safe for the health of the pregnant woman and the fetus. The main possible side effects of diphenhydramine include drowsiness, headache, dizziness, dry mouth, difficulty urinating.

Antihistamines are breastfeeding

Very few drugs are contraindicated during breast-feeding. Although it is known to be drug passes into breast milk, it is almost always the number is so small that it can not damage the health of the newborn, and is less than one percent of the dose of the drug for an adult. However, during the period of breast-feeding to take medication must be cautious.

Opinions about antihistamines breastfeeding Breast-feeding: feed - and no nails!   rather contradictory - in particular, many believe that taking antihistamines during breastfeeding may reduce the amount of milk. Although research this relationship has not been proven in any way, in the period of breast-feeding in the first few weeks after giving birth receive antihistamines better minimized.

Careful in choosing

Even if as a result of regular intake of antihistamines, a decrease milk supply, these changes are usually temporary - in this case it is better to consult a doctor about the drug or change the deadline. If you reduce the amount of milk was actually caused by antihistamines, after receiving the drug situation will normalize itself.

For nursing mothers medications short-term action rather than long-acting medications that increase the risk of accumulation of the drug components transmitted from the mother's milk in the body of the newborn.

Antihistamines that are considered safe, even for pregnant women and women immediately after childbirth, so many, so to recommend the most appropriate treatment option antihistamines may only doctor. In addition, it must be remembered that in the case of drugs that are used nasally rather than orally, the risk of transmission of the ingredients of the drug to the mother's milk to the newborn much less.