Nizoral during pregnancy - it is better not to use. Like almost all other antifungal medicines, Nizoral, along with a pronounced antifungal activity and has many side effects. One of the most dangerous side effect is liver toxicity. In addition, finally installed as Nizoral affects the pregnant woman and the fetus.

Just confirmed information on the use of Nizoral during pregnancy is not as clinical trials of this drug in pregnant women were not conducted. However, there is evidence of laboratory animal research during which it was discovered that the toxic effects of the drug on the fetus. In this regard, the use of Nizoral during pregnancy is possible only for health reasons and on doctor's orders. In such cases, the instructions sounded phrase: "When the potential benefit to the mother outweighs the potential risk for the fetus."

Nizoral We have a lot of side effects, how it will operate during pregnancy is unknown, but it may be assumed, as they can affect one or another side of pregnancy.

Side effects from the digestive organs

Side Effects of Nizoral can be disorders of the gastrointestinal tract in the form of dry mouth, nausea, abdominal pain, constipation or diarrhea. It is known that during pregnancy a woman is constantly worried about nausea, when using Nizoral it will grow.

It is much more dangerous than the side effects of Nizoral as toxic effects on the liver. These side effects are manifested in the form of nausea, vomiting, transient liver dysfunction. But in rare cases when taking Nizoral patients developed toxic hepatitis Hepatitis - the scourge of our time Were even cases where patients have died from this complication. There were also cases of cirrhosis later. Therefore, manufacturers Nizoral before its application is recommended to check the function of the liver in order to avoid acute or chronic diseases. During the course of treatment should also constantly monitor the functional state of the liver and kidney patients in order not to miss the first symptoms of liver toxicity.

During pregnancy, the liver works with high load, so it is possible that the side effects of Nizoral increase. But because no one checked, the list of side effects, changes in liver function during pregnancy is not reflected.

Adverse effects of the central nervous system

When receiving nizrala may cause headache, dizziness, weakness, fatigue, decreased performance, irritability, drowsiness or insomnia, anxiety Anxiety - how to distinguish normal from disease? . There were also isolated cases of transient increase in intracranial pressure, which manifested themselves in the form of papilledema.

All these side effects can significantly complicate the condition of the pregnant woman, because of the condition of the central nervous system depends directly on the hormonal status of the woman and the hormones are known to support women's reproductive function. It is especially dangerous for pregnant women increased intracranial pressure.

What else can cause side effects nizoral

Nizoral may cause increased bleeding by reducing blood platelet count. In this regard, possible nosebleeds. Reduction of blood clotting during pregnancy is dangerous.

In women, while taking Nizoral may be disrupted menstrual cycle, in men developing gynecomastia Gynecomastia - known since ancient times   - Breast enlargement. This suggests that the body's endocrine disorders occur with a change in hormonal levels. How do they affect the condition of the pregnant woman and the fetus is unknown. It is also possible dysfunction of the adrenal glands.

Danger also orthostatic drop in blood pressure (BP) - a sharp decrease in blood pressure during the transition from horizontal to vertical, that is, from a prone position to a sitting position and from a sitting position to a standing position.

In addition, while taking Nizoral possible hair loss, irritation, itching, and burning of the skin, allergic reactions, photophobia, pain in joints Joint pain - how to understand what is going on?   and muscles (signs of intoxication), an increase in temperature.

Nizoral is not recommended during pregnancy, how to predict the consequences of such treatment for the body of the woman and child is almost impossible. At the same time, a serious condition the patient, if it for some reason does not fit other antifungal medicines, Nizoral appointment can be a way out.

Galina Romanenko

Progesterone is a hormone called pregnancy, because it helps women to conceive, carry and give birth to a child. If the woman's body there is a lack of this hormone, the broken her reproductive function. But today, such a state of learned to treat.

Violations of the menstrual cycle when progesterone is low

Progesterone - a hormone, which provides support for hormonal second phase of the menstrual cycle. If it is not enough, then there are dysfunctional uterine bleeding (DUB). All DMK can be divided into two large groups - anovulatory and ovulatory.

Anovulatory DUB develop during the menstrual cycle, which is not accompanied by ovulation Ovulation - How to determine as accurately as possible? Ie yield egg from the ovary. The egg while after reaching maturity remains in the ovary and releases a large number of female hormones estrogen. Under the influence of estrogens mucous membrane of the uterus (the endometrium) is significantly increased in volume. In this second phase of the menstrual cycle does not occur, because it does not formed corpus luteum (yellow body normally formed in situ ruptured follicle after exit from the egg), which must devote progesterone Progesterone - norm and pathology . Progesterone inhibits the growth of the endometrium, causing it to secrete substances necessary for the implementation of the egg in the uterine wall. Since progesterone anovulyatorom cycle there, the mucous membrane thickens. Finally, in some areas of its blood circulation, which leads to areas of necrosis and bleeding. The mucous membrane is torn away slowly and incompletely, which is accompanied by prolonged bleeding. Such disorders of the menstrual cycle can lead to the development of neoplastic processes in the endometrium.

Ovulatory MQM develop in an inferiority of the corpus luteum, which releases progesterone or a little prematurely ends its operation. When this blood is relatively increased content of estrogen, which expands under the influence of the endometrium. The lack of progesterone leads to uneven and prolonged rejection of the endometrium, which is accompanied by the slim long bloody discharge after normal menstruation.

Treatment of menstrual disorders is to appoint hormones. Depending on the cause DMC appointed or progesterone, or a combination with estrogens.

Pregnancy and low progesterone

During pregnancy, progesterone is the principal hormone that maintains that condition. To the corpus luteum of the ovary to secrete progesterone in sufficient quantities in the first half of pregnancy, the embryo is produced by a special shell hormone - human chorionic gonadotropin (hCG). HCG is a permanent task of stimulating the synthesis of progesterone. After 16 th week of pregnancy the synthesis of hormones incurs matured placenta, there is no need for HCG and the amount of it is gradually reduced.

Lack of progesterone immediately affects pregnancy. First of all, it creates the threat of premature pregnancy termination. This can happen due to the fact that the tone of the muscles of the uterus and the embryo can be simply thrown out of its cavity. Progesterone is actively suppress the motor activity of smooth muscles of the uterus, thus preventing miscarriage Miscarriage - why you lose the most precious thing? . Such action of progesterone has a number of side effects, as the reflex is inhibited and the motor activity of smooth muscles of other internal pelvic and abdominal cavity. In the gastrointestinal tract it leads to chronic constipation, it appears in the biliary tract and bile stasis formation of stones and so on.

Progesterone also contributes to reduced immunity - and the physiological response aimed at preserving the pregnancy. Immunosuppression necessary for the mother of the fetus is not rejected by the body consisting of the foreign protein. Progesterone inhibits aggression by the mother's body in relation to the fetus. But the function of progesterone is backward, the negative side: lowered immunity leads to the development of infections. Very often in pregnant women develop a fungal infection caused by yeast fungi genus Candida.

Progesterone helps the woman in the second half of pregnancy to prepare for childbirth. Under the influence of progesterone soften the ligaments and tendons, allowing the bones of the pelvis to change their configuration during the passage of the fetus through the birth canal.

What if progesterone in the blood of a pregnant woman is not enough

Obstetricians today successfully cope with such conditions. Pregnant women are prescribed medications that contain natural or synthetic progesterone (eg utrozhestan Utrozhestan - corrects the deficiency of progesterone , Djufaston) long courses throughout the first trimester, and in some cases both. It allows a woman to carry and give birth to a healthy baby.

Galina Romanenko