Qudesan - domestic medication containing substances that are produced in human cells, but after twenty years of these substances produced insufficient, resulting in a reduction of the energy potential of the organism. Admission Qudesan able to recover these losses - so it helps to restore the normal life of the entire human body as a whole.

How does kudesan

The structure includes Qudesan natural biologically active substance coenzyme Q10. This substance is produced by all cells of the human body. Cells it is necessary for proper carbohydrate metabolism. The main result of carbohydrate metabolism is to provide energy in the form of ATP. It turns ATP as a result of redox reactions, which are by-products of free radicals.

Coenzyme Q10 is part of enzymes (the enzymes many times accelerate redox processes) therefore clear that reducing the amount results in an overall loss of potential energy. And this in turn means leads to a violation of metabolic processes, because in the future the energy consumed in the formation of proteins, fats and other metabolic Metabolism: The basis of life of all living things .

Coenzyme Q10 is a part of some drugs and biologically active additives to food, including the composition Qudesan. But Qudesan distinguishing feature is that the Coenzyme Q10 is in it in water-soluble state, whereas a fat-soluble substance. This formulation is more convenient because it does not require a fatty meal, which is not useful for all patients.

What happens in the body with a deficiency of coenzyme Q10

With a lack of coenzyme Q10 in the body is disturbed energy production, which leads first to the violations of cellular metabolism and then to cell death. Man feels the general weakness, lethargy, fatigue. First disrupted organs, cells which energy is most needed - the brain, heart, skeletal muscle and smooth. Due to violations of protein metabolism is disturbed immune system - to build the immune cells require protein.

The lack of coenzyme Q10 in the body develops in a variety of diseases, especially is prolonged, chronic, taking certain medications, increased physical and neuropsychiatric load, stress, and in the elderly.

Who can take kudesan

Qudesan prescribed for many diseases and conditions. But the most widely used in cardiology, he found as many cardiovascular diseases accompanied by insufficient supply the heart muscle with oxygen and a violation of its contractile capacity. Such diseases include coronary heart disease (including angina at rest Angina rest - invisible enemy   and stress myocardial infarction), hypertension, various heart rhythm disturbances on the background of myocarditis and rheumatic heart disease, heart disease and so on. Receiving Qudesan myocardial cells provides additional energy heart beats with greater force, thus improving its blood supply, which brings oxygen and nutrients

Today kudesan also often used for cerebrovascular disorders, for example, in ischemic stroke Stroke - a serious brain injury   and the consequences of hemorrhagic stroke. The work of brain cells (neurons) is very important to supply them with oxygen. Improved heart function leads to an improvement of cerebral circulation, and thus to a better supply of oxygen neurons.

Kudesan widely used in pediatric patients, it is used as part of combination therapy for the treatment of a variety of diseases, including encephalopathies of various origins, myocarditis, rheumatic heart disease, gastrointestinal disease, and so on.

Qudesan used not only for the treatment of these diseases, but also to prevent them.

Side effects and contraindications

Side effect is extremely rare, as the basis of this drug is a natural substance. However, occasionally there are side effects from the gastrointestinal tract. It nausea, vomiting, diarrhea. Allergic reactions are also possible.

Contraindications reception Qudesan are hypersensitive to the components of the drug by the body of the patient during pregnancy, infant feeding Breastfeeding - a personal choice   feeding, and children up to a year. With care it is recommended to take a low blood pressure.

Qudesan - a drug that is used today in many diseases.

Galina Romanenko

To all tissues of the human body was normal metabolic processes, need certain macronutrients and micronutrients. For example, potassium and magnesium regulate the cardiovascular system. With a lack of these substances deteriorating power of the heart, heart rate changes. Therefore, when such violations appointed Pananginum - a drug that contains salts of these macronutrients: asparginat potassium and magnesium asparginat.

How does Pananginum

Potassium and magnesium - it is the ions within the cells whose content should be higher than in the extracellular space. They provide an interaction between the molecules and the work of many enzymes.

The ability of the myocardium (heart muscle) to the cuts depends on the ratio of sodium, potassium, magnesium and calcium in cardiomyocytes (muscle cells) and in the space around them. If the content of potassium and magnesium in the cells decreases, myocardial contractility decreases, there are infringements of heart rate. This also leads to high blood pressure and atherosclerosis of the coronary arteries (the blood vessels that are responsible for blood supply to the heart).

Potassium regulates metabolic processes in myocardium, prevents the development of tachycardia (heart rate over ninety per minute), normalize heart rhythm. It slows the growth of atherosclerotic plaques that narrow the lumen of the coronary vessels. Due to this the myocardium is getting enough oxygen to function properly.

Magnesium affects the metabolism of proteins and carbohydrates, reduces the heart rate and reduces the need for cardiac muscle for oxygen. This enhances macrocell small lumen arteries, including coronary, thereby increasing blood flow through them.

The combination of potassium and magnesium in a single preparation due to the fact that usually there is a deficiency in these macrocells simultaneously. Furthermore, such a combination, they reduce the toxicity of cardiac glycosides - drugs that are often prescribed for patients with heart failure. Pananginum available as a solution for intravenous injection, and tablets.

Indications and Contraindications

Indications for use of tablets and solution preparation:

• Chronic heart failure, post-myocardial infarction (as a component of combination therapy);
• Cardiac arrhythmias (especially ventricular arrhythmias);
• Treatment of cardiac glycosides (as an additional drug).

It is also recommended to take Pananginum tablets with insufficient intake of potassium and magnesium with food. The drug may be designated in the treatment of diuretic drugs that do not have a potassium-sparing effect.

Panangin in the form of tablets and solution for intravenous injection is contraindicated in the following conditions:

• Renal failure (acute or chronic);
• Oliguria (a condition in which the amount released per day urine does not exceed five hundred milliliters) and anuria (a condition in which urine is supplied into the bladder Urinary bladder - structure and function Because of this it is no longer allocated);
• Addison's disease (an endocrine disorder in which the adrenal glands stop producing the right amount of hormones);
• Atrioventricular block (violation of nerve impulses from the atria to the ventricles of the heart);
• Cardiogenic shock (serious condition, which is characterized by a sharp decline in the ability of the myocardium to cuts, drop in blood pressure and a significant decrease in the blood supply of all organs and systems of the body);
• Elevated levels of potassium and magnesium in serum;
• Hypersensitivity of the components of the drug.

Panangin tablets are not indicated for:

• Myasthenia gravis (severe muscle weakness and fatigue);
• Hemolysis (destruction of red blood cells - red blood cells);
• Dehydration;
• Amino acid metabolism disorders;
• Acidosis (decrease in blood pH) due to any metabolic disorders.

During pregnancy (especially in the first three months) and during lactation Breast-feeding: feed - and no nails!   the drug should be taken with extreme caution.

Side effects

Before the drug can cause side effects of the various systems of the body:

• From the nervous system: paresthesias (tingling, numbness, pins and needles) sensation of heat, dizziness, seizures.
• Since the cardiovascular system: disturbances of nerve impulses from the atria to the ventricles of the heart, the emergence of early heart beats (extrasystole), low blood pressure, redness of the skin on the face, phlebitis (inflammation of the walls of the vein), thrombosis Thrombosis - the cause of heart attack and stroke   veins.
• From the digestive tract: a burning sensation or discomfort in the area of ​​the pancreas (typical for patients with gastritis or cholecystitis with very low acidity of gastric contents), dry mouth, nausea, vomiting, diarrhea. In very rare cases can appear abdominal pain Abdominal pain: Types and Symptoms , Bloating, ulceration of the mucous membrane of the stomach and intestines, bleeding from the blood vessels of these organs, perforation of the intestinal wall.
• On the part of the respiratory system: changes in frequency or depth of breathing.

Interaction with other drugs panangina

If Pananginum used in conjunction with diuretics, which have potassium-sparing effect (veroshpiron, triamterene), β-blockers (metoprolol), heparin, ACE inhibitors (Enap, lisinopril, fosinopril), non-steroidal anti-inflammatory drugs (Voltaren, nimesulide), the significantly increased risk of hyperkalemia (high potassium content in blood serum). This condition is dangerous to the development of serious arrhythmias, or heart rate may cause cardiac arrest. Therefore, while taking these drugs need to constantly monitor the level of potassium in the blood plasma.

Pananginum reduces the efficacy of certain antibacterial agents (such as tetracycline, neomycin, streptomycin, polymyxin B). When concomitantly with cardiac glycosides action of the latter is reduced.

Before you start taking Pananginum, you need to consult a doctor and undergo the necessary examination. Under these conditions, treatment will be most effective.