Hypoplasia of the thyroid gland in children - a congenital disease caused by a deficiency of iodine in the body of a pregnant woman or a hereditary deficiency of enzymes involved in the synthesis of thyroid hormones. It is important to identify this disease right after birth.
The main functions of the thyroid gland
The main function of the thyroid gland is the formation and release into the blood and lymph hormones that regulate metabolism
Improves metabolism and losing weight without dieting
in cells, and thus regulating the processes of growth, development and differentiation (acquisition of cell properties specific to a particular tissue) tissues.
Thyroid cells absorb and accumulate iodine, and then it was synthesized from the amino acid tyrosine and thyroid hormones - thyroxine
Thyroxine - the main thyroid hormone
(T4) and triiodothyronine (T3). The human body does not produce iodine, so for the proper functioning it must regularly deal with food and water. Regulates the secretion of thyroid hormone
Thyroid hormones: mechanism of action and physiological effects
with the help of the pituitary thyroid stimulating hormone (TSH), and the synthesis and secretion of TSH is regulated by hormones of the hypothalamus and thyroid hormones (the more thyroid hormone in the blood, the greater the need to TTG and vice versa).
With a lack of iodine in humans develop symptoms of deficiency of thyroid hormone - hypothyroidism. Most suffer from iodine deficiency, pregnant women: this may affect the development of the thyroid gland in the fetus, that is, cause it to hypoplasia or aplasia.
Symptoms of thyroid hypoplasia in the newborn
Hypoplasia of the thyroid gland - is a congenital anomaly of the prostate, which is accompanied by insufficient development of breast tissue and decrease its function. Hypoplasia develops in the womb because of a shortage of iodine in her body.
Deficiency of thyroid hormones in the blood leads to the rapid development of significant breaches in the body of the child, especially if a significant hypoplasia.
Suspect the presence of hypoplasia of the thyroid gland in the newborn child can be the case if the child is lethargic, sleeps a lot and not breastfeeding, she had no reaction to bright objects and loud sounds. A sign of hypoplasia of the thyroid gland may also be prolonged physiological jaundice and chronic constipation.
Further development of hypoplasia of the thyroid gland in the baby
Depending on the degree of underdevelopment and manifests mostly lag in the physical and psychological development. Such children have a poor appetite, constant lethargy and sleepiness, almost does not develop, or it develops very slowly, there is hoarseness.
There is abnormal development of the musculoskeletal system: long bones shorter, dense, long-term growth areas are not closed. The skull has a distinctive shape, deformed downward. Parietal and frontal bones thicken.
The appearance of the child is very characteristic: small stature, short limbs, bulging belly, big head, puffy face, broad nose, open mouth (tongue may be increased in size) and a meaningless expression.
Children with thyroid hypoplasia have a peculiar character: they are closed, unsociable, sluggish, unsociable. Sometimes these children are flashes of aggressiveness or bouts of depression
Depression - a little more than a bad mood
But they do not stay long, if others are child friendly. Psychological development can vary from small disturbances (mild retardation) to significant changes and even a complete idiot.
Mild hypoplasia of the thyroid symptoms of the disease can be lethargy and lack of alertness of the child, combined with a slight increase, clumsy movements, and some delays in speech development.
Diagnostics
Hypoplasia of the thyroid gland of the fetus is rarely detected during pregnancy. Therefore, all newborns taken blood test for thyroid stimulating hormone - TSH. When hypoplastic thyroid function it will be reduced, that is in the blood is low T3 and T4 hormones. The amount of TSH is always elevated.
The child, who has shown great blood levels of TSH, a fully examined: carried ultrasound of the thyroid gland, bone age X-ray of the child and determine the level of thyroid hormones and TSH levels.
If the diagnosis of hypoplasia of the thyroid gland was installed on time and assign adequate treatment (replacement thyroid hormone therapy), the irreversible changes in the brain tissue can be avoided and the child is developing according to its age.
Galina Romanenko
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- hypoplasia of the thyroid gland