No-spa - lowers the tone of smooth muscles - How does

May 20, 2010

  • No-spa - lowers the tone of smooth muscles
  • How does

How does

No-spa (INN - drotaverine) - is myotropic antispasmodic action, ie it removes an increased tone of smooth muscles. All the muscles of our body are divided into skeletal, enabling the movement of the skeletal system, and smooth, located in the internal organs and blood vessels. No-spa is only effective on smooth muscle, limiting the influx of calcium ions to it. Calcium ions play an important role in regulating the functioning of the body. Penetrating into the cells, they activate intracellular bioenergetic processes, ensuring the realization of physiological functions of the cells, including their reduction.

Nospanum reduces smooth muscle tone of the internal organs and their locomotor activity (including peristalsis) and moderately dilates blood vessels. It relieves smooth muscle spasm caused by both the central nervous system, and direct effect on the smooth musculature located in the gastrointestinal tract, biliary tract, urinary tract and vascular system. In this no-spa does not have serious cardiovascular side effects (ie, does not inhibit the contractility of the heart muscle), it has no effect on the autonomic nervous system that innervate the internal organs and blood vessels, does not penetrate the central nervous system.

When intravenously effect shpy manifested in two to four minutes, and the maximum effect is 30 minutes.

Used Nospanum for the prevention and treatment of functional status and pain caused by spasm of smooth muscle and is available in tablet form for oral administration at a dose of 40 mg and 80 mg (no-spa forte) and as a solution for injection in vials.

 How does | No-spa - lowers the tone of smooth muscles

Indications and contraindications for the appointment shpy

No-spa is used for the prevention and treatment of functional disorders and pain caused by spasm of smooth muscle:

  • Biliary in inflammation of the gallbladder and biliary pitey (cholecystitis, cholangitis, including calculous, ie the formation of stones);
  • gastrointestinal ulcers in the stomach and duodenum, gastritis, inflammation of the small and large intestine (enteritis, colitis), spastic constipation;
  • urinary system in inflammatory processes and kidney stones Kidney stones: identify and treat  Kidney stones: identify and treat
   and urinary tract;
  • reproductive system painful menstruation, to weaken uterine contractions and cervical spasm relief in childbirth;
  • circulatory system spasm of peripheral arterial vessels (for example, endarteritis, accompanied by intermittent claudication), cerebral vascular headaches;
  • for the prevention of spasms of smooth muscles of internal organs during the instrumental studies (eg, endoscopic studies of the gastrointestinal tract - fibrogastroscopy, colonoscopy Preparing and conducting a colonoscopy: the risks and alternatives  Preparing and conducting a colonoscopy: the risks and alternatives
   and so on).

Admission shpy contraindicated:

  • if you are hypersensitive to the drug;
  • with severe renal failure, liver;
  • for serious violations on the part of the cardiovascular system: heart failure (the heart muscle is unable to cope with its function of pumping blood appear edema and congestion of blood in the internal organs), conduction disorders, low blood pressure;
  • children under the age of one year (tablets).

With caution, only after consultation with the doctor, but the silos used for atherosclerosis of the blood vessels that supply blood to the heart, prostate cancer Adenoma of the prostate - how to help a man?  Adenoma of the prostate - how to help a man?
 , Increased intraocular pressure, pregnancy and breastfeeding Breast-feeding: feed - and no nails!  Breast-feeding: feed - and no nails!
   child.

 How does | No-spa - lowers the tone of smooth muscles

Side effects that may occur while taking shpy and drug overdose

When receiving shpy may cause the following side effects:

  • from the gastrointestinal tract: nausea, constipation;
  • From the nervous system: headache, dizziness, insomnia;
  • on the part of the cardiovascular system: heart palpitations, lower blood pressure;
  • hot flashes, sweating, and allergic reactions.

When administered intravenously, were cases of a sharp decline in blood pressure (up to collapse), the development of heart block (conduction disorders of heart rhythm disorders pulses), depression of the respiratory center with breathing disorders.

In overdose shpy sharply amplified all the side effects up to cardiac arrest and breathing.

No-spa - an efficient antispasmodic that can be taken on their own patients for pain and other emergency cases after prior agreement with your doctor.

Galina Romanenko


Article Tags:
  • but shpa

Flatulence - when you need to worry about? - What is flatulence

November 9, 2008

  • Flatulence - when you need to worry about?
  • What is flatulence

What is flatulence

Flatulence - a surplus accumulation of gases in the gastrointestinal tract due to the increased formation of or insufficient removal from the intestine.

The quantity of gases in healthy people depends on the nature of food, age, lifestyle, and other factors. Under normal conditions, the gases accumulate typically in the stomach and in the right and left bending colon. These gases are formed due to swallowing air discharge them in the process of digestion in the stomach and intestines, as well as the neutralization of gastric juice soda (received heartburn). Gases derived through the rectum, part - absorbed into the blood and then released through the lungs.

 What is flatulence | Flatulence - when you need to worry about?

The composition of intestinal gas

Gas in the colon of healthy people is the following: nitrogen - 24-80% oxygen - 0, 1-2, 3% hydrogen - 0. 6-47%, methane - 0-26% carbon dioxide - 4 3 -29%, there is also hydrogen sulfide. The greater the concentration of oxygen stomach and in the intestine - carbon dioxide, methane and hydrogen sulfide.

 What is flatulence | Flatulence - when you need to worry about?

Causes of flatulence

For reasons of occurrence are six forms of flatulence:

  • nutritional flatulence - occurs by eating foods rich in fiber and starch (beans, cabbage, potatoes, black bread and other.);
  • flatulence to the damage of the digestive processes (when the enzyme deficiency, malabsorption, dysbacteriosis, etc.);
  • mechanical flatulence - with a variety of mechanical obstacles to the movement of food (for example, a tumor);
  • dynamic flatulence - occurs on the basis of violations of motor activity of the gastrointestinal tract (for example, toxic effects on the muscles of the intestine at different infections);
  • circulatory flatulence - in circulatory disorders (for example, stagnation in the veins of the intestine with varicose veins).
  • psychogenic flatulence - against the background of mental disorders, such as hysteria.

 What is flatulence | Flatulence - when you need to worry about?

How does flatulence

For flatulence are typical complaints of bloating and heaviness in the stomach, sometimes - aching pain in different parts of the abdomen. Pronounced flatulence may be bouts of cramping pain (gas colic), subsides after passing flatus. In some cases, there is a frequent and noisy carminative, in others - their delay.

There are also belching Belching: why it happens and that means  Belching: why it happens and that means
 , Nausea, constipation or diarrhea, unpleasant taste in the mouth, loss of appetite. Chance of halitosis, in some cases, especially in young people, it can cause a neurosis Neurosis - reaction to the nervous shock  Neurosis - reaction to the nervous shock
 .

Discomfort can occur in other organs: a burning sensation in the heart, heartbeat, disruption of the heart, headaches, muscle pain, sleep disorders, anxiety, depressed mood, weakness, fatigue, etc. Sometimes it bothers shortness of breath, which can be quite strong (dyspeptic asthma).

 What is flatulence | Flatulence - when you need to worry about?

Treatment flatulence

If bloating is often worried, you should see a doctor to rule out a serious illness. Treatment is carried out after the establishment of the causes of flatulence. Appointed diet with the exception of cabbage, beans, fresh bread. Limited to foods rich in starch (potato flour dishes), and digestible carbohydrates (sweets, cakes, ice cream).

Of Pharmaceuticals appointed substance adsorbed on their surface the gases such as activated charcoal Activated carbon - old but indispensable  Activated carbon - old but indispensable
 , White clay, smectite Smecta - necessary in any medicine cabinet  Smecta - necessary in any medicine cabinet
 .

Other treatment is carried out taking into account the reasons that caused flatulence: the enzyme deficiency appointed enzymes at a dysbacteriosis (decrease in the number of beneficial microorganisms in the gut and increase harmful) - Restoration of normal intestinal microflora. When the pain prescribers, relieving muscle spasm stomach and intestines (antispasmodics, for example, no-spa). Is the treatment of constipation and diarrhea.

Flatulence associated with mechanical disturbances, sometimes surgery is necessary.

 What is flatulence | Flatulence - when you need to worry about?

How to prevent flatulence

To prevent bloating, the need for rational balanced diet. Fashionable diet is better to exclude all - they all somehow hurt the gastrointestinal tract.

The next requirement - enough age-appropriate physical activity. If the person does not move, all the muscle, including muscles of inner organs, start to operate in a reduced activity, leading to stagnation and flatulence.

If you have constipation, you should not abuse of laxatives and enemas, it also has a negative effect on the gastrointestinal tract. We need to see a doctor and he will assign the correct treatment.

Remember, flatulence can be a signal of the body of some troubles, so to understand this question is very difficult, it is best to consult a doctor.


Article Tags:
  • flatulence




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