Enterofuril - is antimicrobial broad-spectrum treatment for intestinal infections, a derivative of nitrofuran. Available in the form of capsules and oral suspension. Used Enterofuril intestinal infections, it inhibits the activity of pathogenic microflora and has no negative impact on the microflora.

The mechanism of action Enterofuril

Enterofuril (INN - nifuroxazide) - is intestinal antiseptic broad-spectrum, which is available in capsules of 100 and 200 mg in the form of a suspension for oral administration in vials of 90 ml (5 ml suspension contains 200 mg nifuroxazide). Manufacturer Enterofuril - pharmaceutical company Bosnalek (Bosnia and Herzegovina). Other pharmaceutical companies nifuroxazide sold under the name diastat and ersefuril Ersefuril - to cope with a slight diarrhea of ​​infectious origin .

Enterofuril is nitrofuran derivatives and possesses a broad spectrum of antimicrobial action. The mechanism of action of this drug is associated with breach of enzymatic redox reactions in the cells of the infectious agents, that leads to suppression of life and destruction of cells (if the drug is used at high doses).

Sensitivity to enterofurilu show gram-positive and gram-negative microorganisms - pyogenic streptococci and staphylococci, clostridia, pathogenic strains of E. coli, Salmonella, Shigella, Klebsiella, and others. A special feature of this drug is that it does not develop a habit of pathogenic organisms. Furthermore, it does not suppress the vital activity of beneficial intestinal bacteria and causes of dysbacteriosis.

After taking the capsules or suspensions Enterofuril into its active substance almost not absorbed in the intestine and acts locally, in its lumen, and then excreted in the feces. How quickly Enterofuril be removed from the body, it depends not only on the dose and on the motor activity of the bowel.

Indications and contraindications

The indications for use are Enterofuril acute intestinal infections Acute intestinal infections - the most common disease in the autumn and summer And chronic enteritis infectious nature, but only if the patient no signs helminthic infestations. If the patient has signs of dehydration, then simultaneously with the appointment of Enterofuril spend and dehydration therapy (restoration of water-salt balance).

Contraindications for use Enterofuril is a heightened sensitivity to the nitrofuran derivatives and the neonatal period (up to the age of one month). With caution the drug is prescribed to preterm infants. As part of the capsules and suspensions Enterofuril include sucrose, this drug is not recommended for use in the enzymatic deficiency (congenital saharaznoy failure), characteristic of some patients.

How to take

Enterofuril appoint a doctor, the dose depends on the age of the patient. Adults and children over seven years appoint one capsule (200 mg) four times a day, that is 800 mg per day. The course of treatment - a week.

Children two to seven enterofulil administered in a daily dose of 600 mg (in capsule or 200 mg of 5 ml suspension three times a day). With one month to two years Enterofuril Enterofuril - help with the intestinal infection   prescribed only in the form of a suspension, to which is attached a special measuring spoon. Babies first half-lives (from one to six months), the suspension Enterofuril administered by half the measuring spoon (2, 5 mL - 100 mg) 2-3 times a day. Babies from seven months to two years Enterofuril designate 100 mg (also 2, 5 ml) four times a day.

The suspension before each use should be thoroughly shaken. The duration of treatment should not exceed the week for all ages.

Side effects

Since this drug is very little absorbed in the gastrointestinal tract and has practically no action in common, it is well tolerated. In this regard, it can be administered during pregnancy and breast- Breastfeeding - a personal choice   feeding. Sometimes the side effects can occur in the form of allergic reactions.

Nitrofurans feature of all is their incompatibility with alcohol, when receiving the last teturamipodobnye reactions may occur as a fall in blood pressure, nausea, vomiting etc. In connection with this feature of nitrofuran drugs used to treat a number of chronic alcoholism.

Enterofuril - is an effective antibacterial drug to treat an intestinal infection, which are sensitive to the majority of agents of intestinal infection. Getting used to the drug of infectious agents does not develop at the same time it does not suppress the normal intestinal microflora.

Galina Romanenko

Dyspepsia, indigestion - the term used for one or more symptoms associated with disorders of the digestive process, including sensations of fullness after a meal, heartburn, stomachache Abdominal pain: Types and Symptoms . Dyspepsia - quite common in adults, and can be observed sometimes, and every few days.

Dyspepsia can cause a variety of disorders of the digestive tract - for example, diseases such as gastroesophageal reflux disease, gastric ulcer or duodenal ulcer, cancer, disorders of the gall duct and pancreas. With proper treatment, the disease that caused the indigestion, the symptoms usually disappear.

Sometimes, however, the exact cause of dyspepsia remains unclear. This type of indigestion is called functional dyspepsia. Further, dyspeptic symptoms may be caused by disturbance of normal function of the muscles of the esophagus to ensure movement of food into the small intestine.

Symptoms of dyspepsia

Among the most common symptoms of dyspepsia are:

• Feeling of fullness even when using small portions of food.
• The unpleasant feeling of heaviness in the stomach.
• Epigastric pain - pain and discomfort in the area between the lower part of the chest and the navel. The pain can be intense or insignificant.
• Epigastric burning or heartburn.

Where less common dyspeptic symptoms associated with digestive problems - nausea and bloating. These symptoms may be caused by not only dyspeptic but also other disorders.

Since itself indigestion can be a sign of a more serious disease, if you notice the following symptoms should seek immediate medical attention:

• frequent vomiting
• blood in vomit
• weight loss or appetite
• difficulty or pain when swallowing food
• pain in the stomach area is epigastricheskoy
• digestive process is accompanied by pain in the jaw, neck, arms, shortness of breath, sweating
• dyspeptic symptoms do not disappear for a long time (over two weeks)

Treatment

In the lungs, sporadic cases of dyspepsia relieve symptoms of digestive disorders and prevent their occurrence is possible without medication, following a few simple rules:

• Eat small meals, chewing slowly and carefully
• refrain from smoking, drinking coffee, alcohol, carbonated drinks
• refuse medication, irritate the stomach lining - such as aspirin or anti-inflammatory drugs
• get plenty of rest

One of the main tools for suppression of the symptoms of dyspepsia - preparations of antacids and medications that reduce acid production, as well as drugs that stimulate intestinal peristalsis. Most of these drugs can be purchased over the counter without a prescription.

• Antacids - the main group of drugs that are recommended to suppress the symptoms of dyspepsia. The composition of such preparations include a combination of three different main types of salts - magnesium, calcium, and aluminum, as well as hydroxide or bicarbonate ions which neutralize stomach acid. Antacids, however, can cause a number of rather unpleasant side effects: magnesium salts can cause diarrhea and aluminum salts - constipation. To reduce the risk of side effects, in preparations and often combined salts of magnesium and aluminum.
• H2-blockers - another type of drugs used for treatment of dyspepsia. Such formulations - including ranitidine Ranitidine - help in the prevention of relapse of peptic ulcer , Cimetidine, famotidine, nizatidine - available either by prescription or over the counter. H2-blockers reduce the level of acidity of gastric juice, but act more slowly than antacids. The main side effects that can cause these drugs - headache, nausea, vomiting, diarrhea, and constipation.
• Proton pump inhibitors - omeprazole, lansoprazole, pantoprazole, rabeprazole, esomeprazol - drugs available only by prescription. Proton pump inhibitors - drugs are more powerful than the H2-blockers, but operating on the same principle, that is, reducing the acidity of gastric juice. Proton pump inhibitors are particularly effective in suppressing the symptoms of dyspepsia with gastroesophageal reflux. Side effects of these drugs - back pain, cough, headache, dizziness, abdominal pain, flatulence, nausea, vomiting, constipation or diarrhea.
• Prokinetics - e.g., metoclopramide - help in the case where digestive problems caused by too slow process of digestion. Prokinetic stimulate the muscular activity of the digestive tract, accelerating the movement of food through the esophagus. The main side effects of prokinetic include drowsiness, depression Depression - a little more than a bad mood , Irritability Irritability - you try to control my temper , Seizures.