Phosphogliv derived from phospholipids of soybean seeds with the addition of the sodium salt of glycyrrhizic acid from licorice root as the improved analogue of the well-known drug Essentiale, which is used to restore and protect liver cells.
What are the characteristics of phosphogliv
Phosphogliv - it hepatoprotector (drug protects and restores the liver cells) with immunomodulating and antiviral properties. A feature of the preparation is that fosfatidipidov and complex salts of glycyrrhizic acid (compared with Essentiale containing only phospholipids) enhances the reducing and protective action on liver cells. Also, glycyrrhizic acid salts possess antiviral and immunomodulatory properties, which is especially important in the treatment of acute and chronic hepatitis, viral origin.
Phospholipids bulk of which is phosphatidylcholine, are part of cell membranes of certain intracellular elements (organelles), liver cells (hepatocytes). Strengthening membrane phosphogliv able to restore the state of hepatocyte damage and protect them from external influences. It also restores and activates the protein and fat metabolism in hepatocytes, and prevents loss of cells, enzymes and other biologically active substances involved in the process of cleansing the blood of toxic substances entering it from the outside and formed during metabolism
Metabolism: The basis of life of all living things
. Phospholipids not only prevents destruction of hepatocytes, they also inhibit proliferation of connective tissue in the liver, that is, reduce the rate of development of liver cirrhosis and liver function decline.
Sodium salt of glycyrrhizic acid anti-inflammatory effect and inhibits the virus replication in hepatocytes, and cells of other organs, since cells stimulate the formation of interferon and activates cellular immunity
Immunity - types and characteristics in children in adults
. This component is also due to detergent (surface-active) actions fasfatidilholina provides emulsification in the intestine.
Phosphogliv also has a positive effect on the skin cells, restoring the state of their membranes and removing inflammation. This contributes to suppression of infection and inflammatory or allergic processes in the skin.
Phosphogliv produced (Pharmstandard, Russia) in capsules and as a freeze-dried product for intravenous injection. Capsule phosphogliv protects from degradation in gastric acidic medium and allows it to be absorbed in the duodenum as a constituting component, and as the active products of their decomposition, which better droop into liver cells, skin and other organs.
With which diseases and how to appoint phosphogliv
Phosphogliv prescribed for diseases of the liver. He will, as in acute and chronic diseases, including viral origin - acute and chronic hepatitis, gepatozah (metabolic liver disease), toxic (such as the abuse of alcohol, prolonged use of hepatotoxic drugs, and so on).
Particularly effective phosphogliv liver cirrhosis, since not only restores the liver cells, but also it inhibits the development of connective tissue. Connective tissue with cirrhosis grows in place of dead hepatocytes, slowly and steadily reducing the function of the liver.
Applied phosphogliv and chronic skin diseases, mainly allergic origin. It can suppress or stop the spread of skin diseases like atopic dermatitis, eczema
Eczema - is difficult to treat
and psoriasis, which is based on autoimmune processes (allergic to its own tissues).
Phosphogliv Capsules taken orally with meals, drinking water, 1-2 capsules 3-4 times a day on average during the month. The course of treatment is established, and the doctor is in acute liver processes month, and chronic - from six months to a year.
The lyophilizate is dissolved in pyrogen-free water for injection and injected very slowly twice daily every 12 hours for 10 days and then transferred to the drug in capsules.
Contraindications for use phosphogliv and side effects that can develop in its application
Contraindications for use phosphogliv are pregnant, breast-feeding
Breastfeeding - a personal choice
feeding, individual intolerance of components and up to age 12 years (clinical trials on children have not been conducted). With care it is recommended to prescribe for diseases of the liver, accompanied by an increase in venous pressure in the hepatic veins.
Because of side effects is known only to the appearance of the skin rash as a result are hypersensitive to the drug.