Prednisolone, like all other glucocorticoids, has on the human action on the level of activity similar to surgery. Therefore, doctors try to prescribe this drug in extreme cases when no other treatment helps.
The use of prednisone in chronic infectious and inflammatory diseases
Prednisolone is used for hard occurring chronic infectious and inflammatory diseases when they are accompanied by considerable swelling and severe pain. Most often, such a purpose it is used in diseases of the joints - arthritis and polyarthritis. It perfectly removes swelling and pain.
Since when sharply reduced immunity simultaneously administered antibacterial or antifungal agents (depending on the cause of inflammatory bowel disease). Prednisone is usually prescribed short courses and in small doses. If you need it for a long assignment, after a course of treatment with prednisolone lifted gradually.
In severe cases of arthritis prednizoloen administered in the form of intraarticular injection - it reduces inflammation, pain, and also reduces the risk of proliferation of connective tissues and disorders later joint function.
The use of prednisone in allergic diseases
In acute allergic processes, such as allergies to medications in the form of anaphylactic shock and angioedema, which threaten the destruction of the patient, prednisone is administered intravenously in high doses. Usually, it causes no side effects and quickly stops the development of an allergic process.
In chronic allergic diseases prednisolone
Prednisolone - against inflammation, allergy and pain, but with complications
try to assign as little as possible and as short courses. It is prescribed for bronchial asthma, chronic year-round and seasonal rhinitis (runny nose).
Dosage forms for topical prednisolone are commonly used in the treatment of skin allergies. Ointment prednisolone administered in atopic dermatitis, neurodermatitis, eczema, allergic contact dermatitis, and so on. Prednisolone perfectly removes swelling and itching of the skin. Applications (including external) prednisone can only be done under medical supervision. For it is addictive, which requires a constant increase in the dose, and it is fraught with numerous side effects.
Used prednisone and autoimmune diseases that are caused by allergies to their own tissue. It diseases such as glomerulonephritis, rheumatoid arthritis
Arthritis - a variety of forms and complications
, Ankylosing spondylitis
Ankylosing spondylitis - a lot of patience is required
and so on.
The use of prednisone with systemic connective tissue diseases
Such diseases include systemic lupus erythematosus, scleroderma
Scleroderma - affects all the organs
and so on. A feature of these diseases is systemic proliferation of connective tissue, which leads to disruption of the function of various organs and systems. In rheumatoid arthritis proliferation of connective tissue in the heart leads to the formation of heart defects. When the disease is important not only to suppress proliferation of connective tissue, but also anti-inflammatory effect of prednisolone, so it is used in rheumatic myocarditis (inflammation of the heart muscle).
Prednisolone suppresses the growth of connective tissue, since it violates the synthesis of proteins - collagen. When systemic connective tissue diseases prednisone appointed short courses as part of an integrated treatment of the disease.
The use of prednisolone as replacement therapy
When adrenal insufficiency (the adrenal cortex produces glucocorticoid hormones), including Addison's disease, is produced by an insufficient number of endogenous corticosteroids, leading to dysfunction of organs and systems.
In this case, prednisone administered as replacement therapy. Thus initially assigned a high dose drug, and then move on to receive maintenance dosage for a long time.
The use of prednisone for eye diseases
Prednisolone an external means (ophthalmic suspensions) are often used in the treatment of ophthalmic diseases, such as chronic allergic blepharoconjunctivitis; inflammation of the allergic nature of the cornea (keratitis) with intact mucosa, sclera and the choroid. Apply as prednisone after traumatic lesions of the eyeball after eye operations with long-term stimulation of the eyeball. In all these cases, prednisone is appointed as a part of complex treatment.
Prednisolone quickly removes phenomena such as inflammation, swelling, pain and itching, so is used for many diseases.
Galina Romanenko