The combination of any drug with alcohol, which has a significant effect on the metabolism
Metabolism: The basis of life of all living things
and on the central nervous system is undesirable, since the effectiveness of treatment is always reduced. Is no exception and ampicillin, which also has a number of side effects that increase the negative effects of alcohol.
Blow to the liver
Ampicillin may have a negative effect on the liver, causing a violation of its functions stagnation of bile in the biliary tract and cholestatic (bile stasis in the background) jaundice. But this side effect seen in some patients, while most patients tolerate ampicillin without whatsoever disorders of the liver. Why is this happening? It is obvious that those patients who have side effects of ampicillin by the liver, the organ has some possibly very minor changes that do not appear in the form of the disease, but are felt when taking substances that have toxic effects on liver.
Alcohol has a direct toxic effect on the liver cells - it kills them, and in their place grow connective tissue cells. That is formed cirrhosis with slow but irreparable decline in the function of this organ.
If the liver from any minor congenital changes affect two concurrent hepatotoxic agents, the consequences can be very different, for example, in the form of minor liver dysfunction, transient jaundice or toxic hepatitis
Toxic hepatitis - the impact of harmful substances on the liver
Which is often the cause of death of patients.
The action on the stomach and intestine
Side effect of ampicillin on the gastro-intestinal tract is also evident, not all patients, most of them suffer ampicillin very well. But some patients while taking ampicillin appear nausea, vomiting and diarrhea, which usually does not require discontinuation of the drug and tested independently. The use of alcohol, which irritates the mucous membranes of the gastrointestinal tract, only exacerbate these symptoms and make the drug unbearable.
But the main danger to the gastrointestinal tract while taking ampicillin and alcohol is that both of these substances help to reduce blood clotting. In chronic gastritis, gastroduodenitis and enterocolitis inflammation of the mucosa of the stomach and intestines prone to ulceration and reducing blood clotting increases the risk of internal bleeding. Of course, a healthy person will not be such complications, but if there are any violations of the gastrointestinal tract (especially from unscreened patients), it is better not to risk it.
Strengthening of allergic reactions
All the antibiotics penicillin group often cause allergic reactions. Including a variety allergic reaction may cause and ampicillin. It may be a small rash on the skin, rapidly spreading and merging hives, swelling of turning into the subcutaneous tissue in the throat (angioedema) and causing respiratory failure, anaphylactic shock, a sharp decrease in blood pressure
Blood pressure - dangerous if his swing?
and loss of consciousness, Stevens-Johnson syndrome, when vast areas of the skin and mucous membranes become a bleeding ulcer. If the patient takes ampicillin, then he may well develop one of these allergic reactions.
Alcohol itself does not cause allergies, but in alcoholic beverages often contain various impurities, which may well cause allergic reactions. Moreover, alcohol can significantly affect the metabolism
Improves metabolism and losing weight without dieting
That may cause blood to enter the allergens amplifying any other allergic reaction.
The simultaneous use of ampicillin and alcohol can magnify the risk of severe allergic reactions.
The impact on the treatment of the underlying disease
Ampicillin prescribed for the treatment of infectious and inflammatory diseases. If the drink alcohol, it will break the body's metabolism, thus reducing the effect of the drug ampicillin. Therefore, it is obvious that you need to make a choice between treating a disease ampicillin and alcohol. From their joint application to the patient better not be.
Alcohol is not compatible with any drugs. In this respect, ampicillin is not the most dangerous tool, however, use of alcohol during the course of treatment with ampicillin can backfire.
Galina Romanenko