Amoxicillin is an active substance in the composition of many drugs intended for the treatment of bacterial infections. It belongs to the group of penicillin antibiotics. In most cases, amoxicillin take the form of tablets and suspensions; with very serious infections, or if oral medication is not possible, an injection prescribed amoxicillin.

Amoxicillin destroys the structure of the cell walls of bacteria which are more vulnerable to external impact and can not normally reproduce. It shirokospektralny antibiotic that can kill the bacteria of various types. However, there are many bacteria that are mutated so that they have become resistant to penicillin antibiotics. In the treatment of infections caused by bacteria, amoxicillin is used in combination with other substances.

When prescribed amoxicillin

Amoxicillin prescribed for the following diseases:

• Bacterial infection of the lungs, such as acute bronchitis Bronchitis - protection if the body has malfunctioned , Chronic bronchitis and pneumonia
• Sinusitis, pharyngitis, laryngitis Laryngitis - deadly , Tonsillitis, or some other upper respiratory tract infections
• Bacterial infections of the middle ear
• Bacterial infections of the urinary tract and kidneys (pyelonephritis)
• Bacterial infections of the skin and soft tissues, including abrasions, abscesses, cellulitis and impetigo bacterial
• Gonorrhea
• Septicemia or blood infection
• Bacterial endocarditis
• Typhoid fever and paratyphoid
• Lyme Disease

How to receive

Amoxicillin in most cases be taken three times a day, every 8 hours (one dose before bedtime Dreams: how to understand our dreams And the other in the morning, and another - in the middle of the day). Assuming it is possible both during the meal and in between meals - this has no effect on the absorption - and drink plenty of fluids, preferably water.

One of the common side effects of antibiotics is shirokospektralnyh colitis. Its first symptom is diarrhea, and the presence of blood and pus in the stool. When these symptoms should immediately consult your doctor.

Amoxicillin in the form of a suspension for the children can be kept at room temperature (below 25C). After 14 days of medication in an open package comes into disrepair and must be thrown away no matter how much is left unused.

Drug Interactions

Previously, women who use hormonal contraception while taking amoxicillin and for seven days after it was recommended to use additional methods of preventing pregnancy, such as condoms. Now, however, it is known that amoxicillin does not affect the effectiveness of hormonal contraceptives.

In rare cases, it reduces the effectiveness of amoxycillin anticoagulants, such as warfarin Warfarin - indirect anticoagulants . During the simultaneous reception of both drugs your doctor may prescribe you a more frequent inspection.

Amoxicillin may delay the output time of methotrexate from the body, thereby increasing the risk of side effects. In order to timely detect it, and may need additional testing. Amoxicillin in combination with allopurinol increases the risk of skin rash as a side effect of the drug. Vaccines against typhoid (Vivotif) should be done not earlier than three days after the end of treatment with amoxicillin, an antibiotic because it reduces the effectiveness of the vaccine.

Probenecid may increase blood levels of amoxicillin. As a rule, if necessary, at the same time taking both drugs, doctors reduce the dose of amoxicillin.

Pills Ampicillin for a long time have become commonplace, many take them without a doctor's prescription. But this is wrong: the rapid cure of the infection may be followed by a complication in the form of undertreated disease, addiction infection ampicillin, intestinal dysbiosis Intestinal dysbiosis - how dangerous it is?   or colitis. Get rid of these effects will be quite problematic.

Action ampicillin

The composition includes tablets ampicillin 250 mg active principle and adjuvants - starch, magnesium or calcium stearate, and talc. Take pills ampicillin for half an hour before eating or two hours after a meal. After oral administration in the gastrointestinal tract is absorbed a little more than half of the delivered dose. If ampicillin is taken with food, it absorbed active substance even less.

The maximum drug concentration in the blood is reached in two hours and held for an hour, it is distributed in the body, penetrating, including the placenta, and brain tissue, and then output mainly in the urine unchanged. Provided this drug and human milk. Ampicillin in large quantities gets into the sinuses, middle ear, the bronchial walls, phlegm, bile duct, kidney and urinary tract, and intra-spinal fluid.

Action ampicillin due to the suppression of metabolic processes in the cell membrane of pathogens. He acts bactericidal, ie, destroys the bacteria cells. Activity ampicillin exhibit all infectious agents sensitive to penicillin, and some pathogens of intestinal infections. But ampicillin powerless against the bacteria secrete enzymes beta-lactamase - these enzymes break down ampicillin. Such bacteria include, for example, some species of staphylococci.

Indications

Ampicillin tablets for oral administration are usually prescribed in infectious and inflammatory processes that cause sensitivity to ampicillin infectious agents and flow is not heavy, and so they can be treated on an outpatient basis. Most often ampicillin tablets prescribed for infectious and inflammatory conditions of bacterial origin in the upper respiratory tract. This purulent angina, exacerbation of chronic tonsillitis, acute sinusitis (sinusitis, frontal sinusitis), exacerbation of chronic sinusitis, acute and chronic otitis, purulent pharyngitis.

Apply ampicillin and moderate course tracheobronchitis, laryngitis (inflammation of the larynx). In severe bronchitis, pneumonia Pneumonia - Symptoms and Causes   pleurisy and ampicillin is used in the form of injections.

Ampicillin tablets can also be used at a moderate course of exacerbations of chronic pyelonephritis, acute and chronic cystitis. At the same time for all chronic diseases antibiotic appointed after sowing strictly biological material on nutrient media, identify the pathogen and its sensitivity to antibiotics.

In diseases of the bile flow and gallbladder ampicillin administered with caution and after consultation of the surgeon as the patient may need surgery.

Will ampicillin in tablets and intestinal infections caused by E. coli, Salmonella, Shigella (agents of bacillary dysentery). But today, ampicillin used for this purpose is not so often - has a more effective treatment for intestinal infections. Quite often ampicillin tablets indicated for the treatment of relapse of chronic arthritis - inflammation of the joints Inflammation of the joints - how to relieve the pain? . Acute arthritis occur usually difficult and require the appointment of ampicillin injection.

Will tablets ampicillin for abrasions, small festering wounds, festering sores.

Contraindications and side effects

Tablets are contraindicated if you are hypersensitive ampitsllina their components by the body of the patient, severe liver disease in violation of their functions and during breast Breastfeeding - a personal choice   feeding (at the time of treatment is recommended to interrupt the mother's breastfeeding).

Be wary appointed ampicillin tablets in pregnancy and renal impairment.

Because of the side effects of pills ampicillin known allergic reactions, nausea, vomiting, diarrhea, abnormal liver function, dysbiosis, colitis, immune disorders, decreased blood clotting.

Pills Ampicillin for a long time and have been successfully used in the outpatient treatment of patients, but this is done only on prescription in compliance with all the indications and contraindications.

Galina Romanenko