Nurofen in any form - in the form of tablets, capsules, gel for external use - ibuprofen active ingredient comprises non-steroidal anti-inflammatory agent. Nurofen - anesthetic drugs used to suppress pain, inflammation, reduce the temperature.

Ibuprofen consisting Nurofen blocks the action of the cyclooxygenase-2 - a substance that converts arachidonic acid into prostaglandins. Prostaglandins are produced by the reaction of an organism to injury and certain diseases causing pain, swelling, inflammation. Nonsteroidal anti-inflammatory agents, and in particular, ibuprofen, which is part of Nurofen, block the production of prostaglandins, thereby inhibiting inflammation and relieve pain. Furthermore, nurofen helps lower the temperature - increased amounts of prostaglandins in the brain causes an increase in body temperature, and Nurofen, inhibiting production of prostaglandins, reduce fever.

Nurofen applied not only to reduce the body temperature and stopping the inflammatory processes, but also to relieve muscular and rheumatic pain, and suppression of headache, toothache Toothache - itself does not take place Neuralgia, recurrent pain. Nurofen is useful for colds and helps to relieve the symptoms of colds and flu.

Forms of Nurofen

• Nurofen tablets and caplets contains standard dose
• Nurofen in the form of a suckable capsules comprising granules of ibuprofen which - after the capsule has been dissolved in a language - can be swallowed without water. The drug in this form is very convenient if you do not have water or other liquid to wash down pill.
• Nurofen in capsule contains sustained release dose of ibuprofen is released gradually in the body for eight hours. Gradual release of the active substances allows for a long time to ease pain (e.g. back pain). The capsule must be swallowed whole - it is not intended for sucking or chewing.
• Nurofen in tablet form from headache and migraine comprising ibuprofen lysine - more soluble than the ibuprofen active ingredient form. Ibuprofen lysine acts faster than ibuprofen, which is part of conventional tablets or capsules Nurofen.
• Nurofen express tablets containing sodium ibuprofen dihydrate - ibuprofen soluble form that acts faster - as well as ibuprofen lysine.
• Nurofen and Nurofen express capsules containing liquid, respectively, and liquid forms of ibuprofen are much faster than other forms Nurofen.

Indications

Nurofen is used in the following cases:

• For any pain, including muscular and rheumatic pain, sprains and dislocations Dislocation - Prevention and Treatment , Back pain, neuralgia Neuralgia - the scourge of the elderly , Dental pain, headache.
• Heat, cold and flu symptoms.

Contraindications

Nurofen should not be taken in the following cases:

• In allergic reactions to aspirin or other nonsteroidal anti-inflammatory drugs (for example, diclofenac)
• At a stomach ulcer or stomach bleeding
• In severe cases of heart failure
• In severe cases of renal insufficiency
• During the third trimester of pregnancy
• When receiving the other non-steroidal antiinflammatory drugs including cyclooxygenase-2

In addition, Nurofen in conventional forms is not recommended for children under twelve years of age (the drug is available separately in special forms for children). In no case can not exceed the dose recommended by the manufacturer.

Ibuprofen is a part of Nurofen quite easy to carry, most people when taking Nurofen no side effects were observed. The most common side effects associated with Nurofen irritable bowel and include abdominal pain Abdominal pain: Types and Symptoms , Nausea, indigestion. To avoid occurrence of such side effects may be taking Nurofen just after a meal. In very rare cases, after taking Nurofen observed ulceration or bleeding in the stomach or intestines. In rare cases, Nurofen and other nonsteroidal anti-inflammatory drugs can cause a severe skin reaction (toxic epidermal necrolysis, exfoliative dermatitis). To avoid these side effects immediately after the appearance of skin rashes or lesions in the mouth caused by nurofenom need to stop taking the drug and seek medical advice.

Nurofen and other drugs

Nurofen is not recommended in combination with high doses of aspirin (more than seventy-five milligrams per day) or other nonsteroidal antiinflammatory drugs because the combination increases the risk of side effects.

The risk of stomach or intestinal bleeding increases Nurofen reception in conjunction with the following medications:

• Anticoagulants such as warfarin
• Antiplatelet agents (dipidridamol, clopidogrel)
• Antidepressants - selective serotonin reuptake inhibitors (fluoxetine, paroxetine, citalopram)

Levomekol - a drug that proved to be excellent in the treatment of septic wounds, because it has antimicrobial and anti-inflammatory effect, can treat the wounds of necrotic masses, restore tissue and enhance local immunity.

Ointment levomekol - mechanism of action

Levomekol - this ointment, which has a combined structure. It consists of antibiotic chloramphenicol, metabolic stimulator methyluracil and excipients, such as polyethylene glycol. This composition gives levomekol ability to fight infection and inflammation, while restoring tissue destroyed by infectious-inflammatory process.

Chloramphenicol has antibacterial (bacteriostatic, ie suspend the vital activity of bacteria) action, it is active against Gram-positive and Gram-negative bacteria (staphylococcus E. coli and other), acting including bacteria that are not sensitive to other antibiotics, spirochetes, rickettsia, agents of trachoma and some other microorganisms. In respect of Pseudomonas aeruginosa maloaktiven chloramphenicol. Because of the negative effects of local chloramphenicol can be noted irritation arising from its use.

Methyluracil refers to the metabolic stimulants. Reduction of the metabolism Metabolism: The basis of life of all living things   in the affected tissues, reduces inflammation, increases local immunity (stimulates the production of white blood cells methyluracil, which are the basis of cellular and humoral immunity), accelerates tissue repair and wound healing (these effects are associated with normalization of nucleic acid metabolism in the mucous membrane). Furthermore, methyluracil stimulates production of a particular protein - interferon, which has antiviral and immunostimulating activity. Methyluracil does not have a local irritant effect on the tissue and is able to provide a light-shielding effect in patients photodermatosis.

Polyethylene glycol ointment provides stability and its adsorption (deposition on the surface of toxic substances, including metabolic products and tissue breakdown) properties.

All these properties of the preparations comprising the levomekol unaffected in the presence of pus in the wound tissue and decomposition products, however levomekol found wide application in the treatment of purulent wounds.

Indications and contraindications for use

Treatment of purulent wounds - it is a complex issue, since pathogens often become accustomed to a particular antibiotic Antibiotics - whether they will help you in the foreseeable future?   and are insensitive to it. Chloramphenicol, which is part of levomekol, is an exception to this rule, as the resistance (immunity) to it is developing quite slowly.

Levomekol indicated for the treatment and prevention of septic wounds, in the first (necrotic) phase of wound healing process. Especially shown levomekol if the inflammatory process caused by mixed microflora. As a result, the wound is cleaned of pus and necrotic mass, decreases swelling Prevention and treatment of edema - it is important to understand the root cause   tissue in the wound area while accelerating the recovery processes in tissues.

Levomekol can treat bedsores, venous ulcers, sluggishly recovering, persistent wounds of different origin and the long-existing deep infected burns.

When used to inhibit wound infections trophic ulcers levomekol provides high anti-bacterial, anti-inflammatory and anti-edematous effect, promotes whiter quality and rapid recovery of the skin.

Levomekol ointment is applied to the sterile gauze pads How to use sanitary pad - basic precautions Which are placed in the wound. You can enter up to the temperature of the human body through the drain tube ointment left in the wound for wound secretions go outside, or through a syringe deep into festering wounds. Dressings with leomekolya should be held every day until complete clearance of the wounds of pus and tissue decay products.

Contraindications for use levomekol is the only individual intolerance of components.

Side effects that may occur when using levomekol

In applying levomekol experience an allergic reaction in the form of various skin rashes. In this case, use of the drug should be discontinued and conduct the necessary anti-allergic treatment.

Levomekol - ointment, which has long been used successfully in outpatient surgery, but on their own to apply it makes no sense - you could end up further spread of infectious-inflammatory process.

Galina Romanenko