Pituitary adenoma - a benign tumor dangerous - Diagnosis

September 18, 2013

  • Pituitary adenoma - a benign tumor dangerous
  • Diagnostics
  • Treatment
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 diagnosis of pituitary adenoma

Diagnosis of pituitary adenomas

Pituitary adenoma - a benign tumor of glandular tissue, which is located in the anterior pituitary. Why begin the development of this tumor studied enough, some believe that the primary changes occur in the hypothalamus, and then formed under their influence pituitary adenoma.

Well-known factors that contribute to this process, an infectious disease that affects the nervous system, head injuries, adverse factors acting on the fetus during pregnancy, hormonal changes, including long-term use of hormonal contraceptives.

All pituitary adenoma divided into hormonally active (they produce hormones) and hormonally inactive (not produce hormones, but they can compress the surrounding tissue). The size of pituitary adenoma divided into small (1 cm in diameter) and large (more than 1 cm in diameter).

 Diagnosis | Pituitary adenoma - a benign tumor dangerous

Symptoms of pituitary adenomas

Manifestations pituitary adenoma depend on whether the hormone producing cells adenomas and adenomas of its growth rate. So, adenoma producing prolactin (a hormone that promotes the development of breast milk) is shown the increase in mammary glands, the release of these milk and menstrual irregularities. This adenoma is found most often grows slowly and sometimes does not manifest.

Adenoma, secreting growth hormone, seen rapid growth in childhood (gigantism) or acromegaly (overgrowth of bones and soft tissue), which is observed in tumors in adults.

When adenoma producing adrenocorticotropic hormone (increased production of adrenal hormones) showing signs of the disease Cushing's weakness, fatigue and constantly in a bad mood (depression), swelling, weakening of the heart, high blood pressure, obesity, the body and the face, combined with atrophy (desiccation) of the limbs. Do women have hirsutism (male pattern of body hair). This tumor grows slowly, but more often than other adenomas goes into a malignant tumor.

Adenoma, produces hormones that stimulate the thyroid, occurs more often in patients with a deficiency of thyroid function. Thus there is an excess of thyroid hormone, which is manifested by weight loss, palpitations, irritability Irritability - you try to control my temper  Irritability - you try to control my temper
 .

The appearance of adenomas, which produces hormones that regulate gonadal function in men causes of impotence Impotence - a female perspective on the problem  Impotence - a female perspective on the problem
   and the emergence of female sexual characteristics (such as breast growth) in women - menstrual cycle, uterine bleeding and infertility.

As the adenoma it can compress the surrounding tissue, causing a variety of symptoms from the central nervous system, such as blurred vision, even blindness.

 Diagnosis | Pituitary adenoma - a benign tumor dangerous

Diagnostic tests

In the diagnosis of pituitary adenomas accounted features of its manifestations, be sure to investigate the blood on hormones, giving a basic understanding of what could cause disease. Radioimmunoassay serum to determine the amount of the pituitary hormones in the blood serum.

Additionally, using radiographic (X-ray of the skull, computer and magnetic resonance imaging) methods.

The grounds for suspicion of pituitary adenoma may be available to the patient's symptoms, its history, and the results of various diagnostic procedures.

Description of symptoms is of great importance for the diagnosis, since it gives the doctor information on the basis of which it can decide what methods should be used for further examination.

During diagnostics necessarily do a blood test, however, as the hormones produced by the pituitary gland is not constant, and at certain time intervals, this may be insufficient to evaluate the function of the pituitary gland, and determine which hormone is produced in insufficient or too much. Therefore, the diagnosis also conducted the following tests:

  • ACTH stimulation test

The patient is administered adrenocorticotropic hormone (ACTH), which stimulates the adrenal glands, and 60 minutes later checked cortisol levels. When the pituitary adenoma violates production of ACTH, the adrenal glands lose their ability to produce cortisol in response to stimulation.

  • Metiraponovy test

This test is also used to determine how pituitary adenoma effect on the production of ACTH. Before bedtime Dreams: how to understand our dreams  Dreams: how to understand our dreams
   the patient is given 12 tablets (3 g), metyrapone, and in the morning take a blood sample to ACTH.

Since metyrapone blocks the production of adrenal hormones, healthy body reacts to this large number of secretion of ACTH. If the level of ACTH in the morning will not be increased, this indicates that the pituitary adenoma has influenced you the production of this hormone.

  • Insulinotolerantny test

In this test the patient to lower blood sugar Blood sugar - one of the main indicators of human health  Blood sugar - one of the main indicators of human health
 Administered insulin. The normal reaction to this is the secretion of ACTH and growth hormone. In patients with growth hormone deficiency and ACTH caused by a pituitary adenoma, this reaction is not observed.

Tests for hormone levels to help confirm the presence of functional adenomas, and take it to Nome or type. Some functional pituitary adenomas, such as prolactinomas, can be successfully treated without surgery, so it is important to analyze hormones before choosing a treatment.

 Diagnosis | Pituitary adenoma - a benign tumor dangerous

Medical imaging in the diagnosis of pituitary adenoma

At the moment the diagnosis of pituitary adenoma commonly used method such as magnetic resonance imaging (MRI). Using MRI can detect an adenoma with a diameter greater than 4 mm. The most powerful magnetic resonance scanners can "see" even smaller adenomas. Although MRI is the preferred tool for the diagnosis of pituitary adenoma, is sometimes used computed tomography (CT).

Some other tumors cause symptoms similar to the symptoms of pituitary adenoma - they must be excluded during the diagnosis. Such tumors include:

  • Craniopharyngiomas;
  • Rathke's pouch cyst;
  • Meningioma;
  • Arachnoid cysts;
  • Granulomatous disease;
  • Metastatic tumors;
  • Chordoma.

Pituitary adenoma - a benign tumor dangerous - Forum

September 18, 2013

  • Pituitary adenoma - a benign tumor dangerous
  • Diagnostics
  • Treatment
  • Forum
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At age 23, he was diagnosed with pituitary macroadenoma more than 4cm in diameter. Sight dropped very quickly. In Kiev, neurosurgery on Manuilskogo transnasal surgery was done (as it turned out the tumor is not garmonaktivnaya), then radiation therapy, the tumor decreased to 2 cm. Now I'm 28, vision was restored, but not the left eye to the end - 0 4.Ezhegodno pass MRI examination. If there is deterioration of vision - an emergency operation, then save your eyesight. And do not be afraid. Deaths one in a million. Are treated and be healthy.
Thank you for the positive mood)))
Many years ago, I, too, was made a diagnosis. Prolactin was increased more than 10 times, hormonal abnormalities were lifetime. In those years it was difficult to surveys, hiking and scored all. Not to say that to feel healthy, but lived. I am now under the 70.Chuvstvuyu not very important, but write off their age. Always cautious and wary of radical methods of treatment and do not think it was wrong.
When detecting any pituitary tumor, consult your endocrinologist, because it is at parts in most cases. They will appoint you as a result of tests and treatment already
What are the forecasts vmeshatel'stvo after surgery and radiotherapy in pituitary adenomas?
I also have a micro adenoma pralaktinoma three years I sney zhyvu radila son but had to do a caesarean sichenie I uhutshaetsya vision pastayanaya headache but doctors neurosurgeon Ghawar ninada nothing to do nada nothing lichit not just watch Do not know what to do
Good day to all! I macroadenoma the left cavity sella is determined by the formation of cystic-solid structures in the size 12 * 14 * 9.1 mm.deformiruyuschy Left Front main pazuhi.soderzhimoe cystic component of high education belka.zaklyuchenie: Mr. -kartina macroadenoma gipofiza.rek Mr. Xia control in dinamike.no papravilas already at 40 kg for 2 goda.analizy all passed - written not gormonalnaya.lecheniya nikokogo! nenaznachili.
Garcia quote:
Brain tumor indicates that the unspiritual man, like a computer, too much rational thinking (head) and a lack of thinking heart.) You should not hostility embraced this Old-people listen!
  Why listen? Stupidity in the world a lot
I quote:
Brain tumor indicates that the unspiritual man, like a computer, too much rational thinking (head) and a lack of heart thinking.
You should not hostility embraced this Old-people listen!
"Uncle Peter, you - fool?" (A) to stop writing such heresy and think, where are the MG-mammalian animals! They, too, too much rational thought ?!
I have a pituitary adenoma (prolactinoma) diameter size was 3, 5cm pressing on the optic nerves, decreased vision -6, 5 am treated pills Dostinex (or kaberlin) for 2 years; Now do an MRI every six months, I hand over analyzes once a month on testosterone, prolactin, and everything is normal, the tumor has decreased to 2, 2 cm or more is not reduced, there is a question about the operation. Consult an endocrinologist in all matters to do when, what to do, because the surgeons just to cut, and no cure. Occupation they have such.
I have a pituitary adenoma prolaktinoma 4 years being treated dostineks initially was deametrom 3 cm. And prolactin rolls over more than 60 thousand times the real dosage of Dostinex picked himself by blood tests, after two months of treatment, prolactin returned to normal, a year later the tumor was reduced in 3 times now with opoholyu not know for a long time did not pass MRI, but feeling good
I macroadenoma pituitary mixed (GH and prolactin), with no signs of growth on the background of drug therapy (size 19-16-21mm). Analyses on hormones handed over good, even like growth factor I below normy.Otvette please if analyzes will always be such a good chance that it will not develop into a tumor of poor quality?
I adrenal hyperplasia. Very high rate of adrenalin, cortisol and aldosterone very low TSH. Since childhood, I felt that I osobennoo suffer like that. But now, then at least I understand what was and is the reason. How is it treated do not know
I was operated on twice, first in 2002, second-2011. After vtrogo intervention recommended to pass obluchenie.Devyat years I have watched the growth of adenomas, and when she began to show itself had operirovatsya.Samochuvstvie good, let's see what will happen after irradiation
I had in 1998 discovered pituitary adenoma, it turned out, the re-examination that she allegedly very small and generally benign.)
and I microadenomas. cycle disorders. Prolactin was always the norm, and now, with the stands colostrum, especially in hot weather. other hormones jump from the bottom up
Oksana if you microadenomas that's fine But I hypophysis adenoma and craniopharyngioma forecasts do not utishitelnye! Sadly ...
Quoting weber:
Brain tumor indicates that the unspiritual man, like a computer, too much rational thinking (head) and a lack of heart thinking. Sign of stubbornness, refusal to change old patterns of thinking.
  Damn where only these idiots come from. You can not certainly make anyone of these diseases, but I would have looked with interest as you muddle, the tumor will be treated purely spiritual.
Quoting weber:
Brain tumor indicates that the unspiritual man, like a computer, too much rational thinking (head) and a lack of heart thinking. Sign of stubbornness, refusal to change old patterns of thinking.
  Hmm, there are also idiots
Brain tumor indicates that the unspiritual man, like a computer, too much rational thinking (head) and a lack of heart thinking. Sign of stubbornness, refusal to change old patterns of thinking.
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