Ursosan - a drug that has a positive effect on liver function, helps to reduce stagnation in the biliary tract and the dissolution of cholesterol gallstones. It possesses choleretic, immunomodulating properties, lowers cholesterol levels and toxic substances in the blood, as well as proliferation of connective tissue in the liver.

The mechanism of action Ursosan

Ursosan (Active ingredient - ursodeoxycholic acid) belongs to a group of medicines - hepatic (positively affect the function of the liver) with choleretic and cholelitolitic (dissolving cholesterol stones) action. It produces this medication Czech pharmaceutical company PRO.MED.TSS capsules of 250 mg. Other pharmaceutical companies, ursodeoxycholic acid, sold under the name urdoksa, urzofalk, ursofalk, Urso 100.

Ursosan mechanism of action is based on the fact that, with the high polar properties ursosan forms nontoxic mixed yarn toxic bile acids lacking polarity. Ursosan able to prevent the aging and death of cells of the liver and biliary tract by a positive impact on their membranes. It also prevents damage to cell membranes in the throwing of bile into the stomach (gastritis biliary reflux) and stomach contents into the esophagus (reflux esophagitis).

Ursosan also stimulates the dissolution of cholesterol in the bile, bile reduces the propensity to stone formation, helps dissolve existing cholesterol gallstones and prevents the formation of new ones. It removes stagnation of bile in intrahepatic ducts and inhibits the process of proliferation of connective tissue in the liver cirrhosis and other diseases. Slow formation of cirrhosis removes the risk of rapid development of varicose veins Varicose veins - the operation is inevitable?   esophagus.

Ursosan also has easy immunomodulatory effects, enhancing the activity of leukocytes White blood cells as the basis of immunity .

Indications and contraindications

The main indications for use Ursosan are cholelithiasis and stagnation of bile in the biliary tract. This drug is used for the dissolution of cholesterol gallstones in the gallbladder in case they can not be surgically removed because of contraindications patient. Assign ursosan and to prevent the formation of stones in the bile duct after removal of the gallbladder.

In addition, ursosan used for any liver disease (acute hepatitis, acute chronic hepatitis, toxic liver damage of various origins, cirrhosis of the liver, and so on) as the gepatotrotektor to reduce the toxic effects on the liver cells, to prevent the proliferation of connective tissue (cirrhosis formation). It is used for the prevention of diseases of the liver with prolonged use of hormonal contraceptives and cytostatics (drugs to treat cancer).

Assign ursosan as to prevent stagnation and formation of stones in dyskinesia (violation of motor activity), biliary tract, throwing bile from the duodenum into the stomach (gastritis biliary reflux) from the stomach into the esophagus (reflux esophagitis).

Contraindications for the purpose Ursosan are hard (they are visible on radiographs) gallstones with a high content of calcium, significant dysfunction of the gall bladder, acute inflammatory diseases of the gallbladder and biliary tract (acute cholecystitis, acute cholangitis), liver cirrhosis with severe complications of the liver and kidney failure, impaired patency of the biliary tract, lactation, hypersensitivity to ursosan.

Despite the fact that ursosan can be administered to children at any age, its dosage form (capsules) does not allow its use under the age of four years. Appoint ursosan during pregnancy can be used only when the intended benefits to the mother outweighs the potential risk to the fetus.

The side effects and the possibility of an overdose

Ursosan well tolerated but side effects are possible, they are few:

• from the gastrointestinal tract - nausea, vomiting, diarrhea or constipation;

• from the liver - a transient liver function abnormalities, calcination gallstones;

• In addition, there may be backache Back pain: Do not start the process , Hair loss, exacerbation of psoriasis Psoriasis - immune system alarm Allergic reactions.

• No cases of overdose Ursosan not met.

Ursosan - is an effective and fairly safe drug.

Galina Romanenko

The disease, which is caused by ureaplasma called ureaplasmosis or ureaplasma infection. The pathogen enters the cells of the mucous membranes of urogenital organs of men and women, causing long flowing and often asymptomatic disease. Signs of the disease are often its complications.

Ureaplasma - what is it

Ureaplasma - this is a very small bacterium that belongs to the family of mycoplasma. A special feature is the absence of full ureaplasmas membrane. This allows ureaplasmas freely pass through the cell membrane and to settle there for a long time - ureaplasmas cells provide all the necessary nutrition. There are two ureaplasmas - urealitikum Ureaplasma parvum and Ureaplasma Ureaplasma parvum - intracellular parasite .

Ureaplasmas peculiarity is the fact that it is using the allocated enzyme cleaves uric acid to ammonia. It promotes the formation of complications from kidney and urinary tract as well as ammonia irritates the mucous membrane of them.

Dispatched ureaplasma This insidious ureaplasma - often too late   mainly through sexual contact, but can be passed from mother to child through the membranes and the passage of the baby through the birth canal during delivery.

Carriage ureaplasmas

Typically, carrier ureaplasmas asymptomatic in women and men. But sometimes the cause of ureaplasma dysbiosis vagina Dysbacteriosis vagina - how to fight?   - Increase of opportunistic and pathogenic microflora in the vagina. This suppressed vital functions of normal microflora, which is represented mainly lactobacilli. Very often vaginal dysbacteriosis (bacterial vaginosis) develops when simultaneously Ureaplasma expands and some other type of opportunistic bacteria such gardnerellas.

Dysbacteriosis - it is not a disease, and predbolezn that has many chances to go in the inflammatory process - is only reduced immunity. But bacterial growth is manifested in the form of the appearance of heavy discharge with an unpleasant fishy odor. Bacterial vaginosis is definitely a need to identify and treat.

Symptoms of inflammatory diseases of the urinary organs of women, caused by ureaplasma

The inflammatory process caused by ureaplasma called ureaplasmosis. In most cases ureaplasmosis Ureaplasmosis - inflammation of the urogenital system   It has blurred over, the symptoms of which can easily be overlooked. Especially characteristic is unnoticeable for the inflammatory process for women. A woman may be ill ureaplasmosis years, which appears only in the course of examination for infertility.

It starts a process of inflammation of the walls of the vagina and the cervical canal (vaginitis and cervicitis). The woman can appear transparent allocation and minor discomfort to go away without treatment. There may be frequent and painful urination - a sign that the inflammation has affected the bladder. Or maybe not at all nor any signs of the disease, it also happens.

However, the inflammatory process subsides, then it starts again and starts moving upward, spreading to internal genital organs of women - uterus and its appendages (fallopian tubes and ovaries). This occasionally can appear minor abdominal pain, isolation (both transparent and mucopurulent - a sign of joining other bacterial infections). Most such aggravation develop after menstruation, which causes worsening of any chronic processes in the genitals and are accompanied by a slight rise in temperature, general malaise, weakness.

Against the backdrop of long flowing inflammatory process in the uterus, fallopian tubes and ovaries grows connective tissue - adhesions, which are the cause of infertility.

Symptoms of inflammatory diseases of the urinary organs of men caused by ureaplasma

In men, Ureaplasma causes the disease, which is also, as in women, goes unnoticed. But men ureaplasmosis symptoms, though small, but still there. Initially, these are signs of defeat of the urethra (urethritis) - frequent painful urination and clear discharge from the urethra in the morning. But sometimes (quite rare) is an acute onset of the disease, with fever, severe disorders of urination and discharge, accompanied by burning and itching.

All these symptoms pass quickly without treatment. However, the infection remains and at any moment can come back to haunt or spread to the internal genital organs, most often on the prostate and epididymis. Signs of internal organs are a pain in the perineum, lower abdomen, in the testicle, fever (sometimes it can not rise, while in other cases increased significantly). Reduced sexual function and can develop infertility.

Ureaplasmosis easily treatable in the early stages of the disease, so for suspected inflammatory process in the field of urinary organs should consult a doctor.

Galina Romanenko