TB bacteria enter the body through the airways and penetrate into the lungs and, in most cases, there are. But sometimes they can get into the lymph nodes and venous blood, and then - spread to other organs. Tuberculosis of the bladder is rare and is not an independent disease - he begins to develop in the kidneys, and then spreads to the genitourinary system, including on the bladder.
This kind of TB developed in about half of patients suffering from renal tuberculosis. In patients with a weakened immune system, genitourinary tuberculosis can lead to kidney damage, and a number of other complications. For example, patients with this type of TB hypertension occurs twice as often as the average.
Tuberculosis of the bladder usually begins with inflammation in the mouth of the ureter, urinary channel narrowing, and development of vesicoureteral reflux - disorder in which urine from the bladder flows back into the ureters. In severe cases, TB affects the entire bladder wall where the deeper layers of muscle tissue is gradually replaced by fibrous tissue. Tubercles (nodules that can form in the tissues affected by TB bacteria) in the urinary bladder are rare; more often they appear in the mouth of the ureter. Upon detection of isolated tubercles at a considerable distance from the mouth of the ureter doctor may prescribe screening for malignant diseases as tuberculosis of the urogenital system such tumors are rare.
It is estimated that tuberculosis
Tuberculosis - a full recovery is not guaranteed
urogenital system accounts for 6% of all cases of extrapulmonary tuberculosis
Extrapulmonary tuberculosis - many forms
; in developing countries the figure reaches 15-20%. In addition, extensive research conducted in the second half of the twentieth century, have identified a variety of prostatic lesions in 10-12% of men who died from tuberculosis. However, autopsy results have not always been enough to determine whether changes in prostate tissues have been associated with tuberculosis.
Before the advent of anti-TB treatment, most patients with urogenital tuberculosis belonged to the age group of 16 to 40 years; in the early 20th century, doctors described the disease as "a disease of young adults." Today, more than 70% of patients with the condition are over 35 years old, 15-20% - over 65 years.
Causes
In most cases, tuberculosis urinary organs is caused by tuberculosis bacteria (Mycobacterium tuberculosis). These bacteria proliferate slowly fall once in 24 hours, and can survive in immune cells after phagocytosis. Much more rare tuberculosis pathogens kidneys and bladder may be bacteria such as M kansasii, M fortuitum, M bovis, M avium-intracellulare, M xenopi, M celatum. Men, like women, the development of varieties of tuberculosis usually occurs after infection with TB bacteria through airborne droplets. The probability of infection through sexual contact is very small, but there are cases where tuberculosis infecting mochevopolovuyu system transmitted through homosexual sex among men. Previously it was assumed that genitourinary tuberculosis can be transmitted through urine, but studies confirm it failed.
HIV infection, prolonged use of steroids or immunosuppressive drugs increases the likelihood of contracting tuberculosis as the urinary organs, and the reactivation of previously cured of tuberculosis.
Symptoms of tuberculosis of the bladder
Patients with this disease are rarely seen classic symptoms of tuberculosis; Tuberculosis is often asymptomatic urinary system.
The most common symptoms of TB of the genitourinary system: an unusually frequent urination (first - in the afternoon, in the late stages of the disease - at night), dysuria, pain during urination, blood or pus in the urine, fever. Tuberculosis of the genitourinary system often leads to frequent infections of urinary tract, which are difficult to treat with antibiotics. Men with this disease often complain of swelling and pain in the testicles. Infertility in men and women, in some cases also a sign of tuberculosis of the urinary system.
Diagnostics
Because the symptoms of TB
Symptoms of TB - how to recognize the disease
genitourinary system are often poorly expressed, for extended periods of time can ignore both patients and doctors. In the differential diagnosis is necessary to exclude violations such as renal cell carcinoma
Carcinoma - how to prevent disaster?
, Epididymitis, hydrocele, spermatoceles, testicular tumors, pelvic inflammatory disease, benign prostatic hyperplasia, urethritis.
In 90% of patients with tuberculosis of the urinary system has a positive Mantoux test, but it only indicates that the human body has the TB bacteria, but does not establish what kind of TB ill patients. To diagnose tuberculosis of the bladder, is also required to conduct a general analysis of blood, urine, sputum analysis secretion of gamma interferon.
It is also used X-ray, computed tomography or magnetic resonance imaging, and in some cases carried ultrasound. If you suspect a malignancy may require biopsy.
Treatment
In tuberculosis of the urinary system is usually an effective course of treatment shorter than in pulmonary tuberculosis - is associated with a lower bacterial load. Standard treatment of pulmonary tuberculosis lasts six months, with genitourinary tuberculosis - four months. HIV-positive patients may be advised to take medication for nine months.
Used in the treatment of isoniazid, rifampicin, ethambutol, pyrazinamide, streptomycin. Severe cases may also be assigned high doses of prednisone for several weeks. If TB leads to serious disturbances in the urogenital system, you may need surgery.