The success of the treatment depends primarily on how quickly diagnosed. Diagnosis of syphilis consists of the clinical features of the disease, as well as a set of methods of laboratory diagnostics. The diagnosis must be clinically justified, accurate and definitely confirmed the discovery of the causative agent.
Importance of clinical symptoms
Diagnosis of primary syphilis should be based on the early detection of the primary tumor disease. The complexity of the diagnostic approach by the fact that the appearance of the chancre may vary considerably. Differential diagnosis of syphilis is carried out with a variety of infectious diseases (such as angina), and skin diseases.
The doctors of any specialty should have knowledge of how to recognize syphilis
Syphilis - punishment of Venus
As the primary site can be located at any place where a person had contact with the agent. Chancre is not only found on the genitals, as well as abdominal, in the mouth, in the tonsils, that is different localization. In the process of carrying out diagnostic measures should pay attention to the dimensions of education. The size of the hearth reaches gigantic proportions, if the chancre is localized in the abdomen or pubic area. There are also dwarf chancre sizes which can be detected in the mouth on the tonsils.
Great importance is attached to clinical symptoms, as in the first period of the disease is difficult to confirm the diagnosis by blood tests. Period during the first four weeks of the primary tumor is considered to be seronegative, so serological studies should be done regularly at set time intervals.
What does the laboratory diagnosis of syphilis
Methods of diagnosis of syphilis include serological blood tests, as well as the study of cerebrospinal fluid and secretions, which can reveal the presence of the pathogen. Serological diagnosis is to identify the antibody titer
Antibodies - "soldiers' immunity
to pathogens. This indirect method, which is used for venous or capillary blood.
Considering that during the serological survey has a certain kind of disadvantages at the present stage are increasingly began to use methods of molecular genetic diagnosis.
Laboratory diagnosis of syphilis, with which identify the sequence of the DNA of the pathogen (or PCR diagnostics) differs most informative in establishing the diagnosis. There are some disadvantages of this method of research, which limits its widespread use:
- the high cost of laboratory equipment
- Reagents used in the diagnostic process, quite expensive
Even at the present stage of development of medicine, not all medical centers can afford to purchase laboratory equipment for PCR diagnosis. Widespread ELISA method, which refers to the standardized methods for serodiagnosis, while highly informative.
Serological diagnosis of syphilis may give false-positive, false-negative results, due to the possible reaction on the part of the antibody in the blood serum. Particular attention should be given if the patient passes inspection, has weighed on the history of rheumatoid diseases. The presence of rheumatoid factor in the blood is one of the causes of false-positive results.
How can you prove the existence of a patient treponem
There are diagnostic methods that allow you to prove conclusively that a person has syphilis. At the primary and secondary syphilis
Secondary syphilis - can proceed unnoticed for several years
can reliably detect the pathogen, that is pale treponemu that will be a confirmation of the diagnosis. Microbiological diagnosis of syphilis consists of microscopy. The method is highly specific, but the accuracy of the result is largely determined by the qualifications of the expert, who conducted the study. The result is also influenced by the application of various antiseptics, which can process the surface of the skin before a fence material.
Microscopy method helps to answer the question of how to determine syphilis, it is not possible to use it to evaluate the effectiveness of specific therapies. If necessary, the dynamic control of the flow of infectious process should apply the methods of serological diagnosis that will give the most relevant results for a specialist from the perspective of informative value of the method of diagnosis.
The incidence of syphilis remains high, so it is important to put into practice the methods of rapid diagnosis, allowing to obtain reliable results within a short period of time.
Rapid diagnosis of syphilis can be used as a method of screening studies of a large number of people, there is no need to resort to costly methods of laboratory diagnostics.
Most people are familiar with the possibilities of modern diagnosis of the disease, so often self-treated in the laboratory to undergo investigation. In order to properly answer the question how to detect syphilis, recommended to get professional advice, which will be able to determine the necessary amount of study, taking into account the period of illness, the presence or absence of clinical symptoms. It has a large value of the time factor, namely, when a study made in terms of the possible period of syphilis. To determine such details should only be a specialist, as the quality of the survey in the future determines the success of the prescribed course of specific therapy.
Marina Solovyov
