Rotavirus infection (RVI) can flow as quickly and quietly, and very hard. It begins often with a sore throat, cough and runny nose, and then join vomiting, profuse watery stools and fever. So why can cause severe course RVI?
The immediate danger when rotavirus infection
The most important risk for severe rotavirus infection is dehydration (exsicosis) caused by repeated vomiting and loose stools. Especially hard to tolerate dehydration small children who have this background may start cramping, various disorders of the cardiovascular system and kidneys.
The effects of rotavirus infection can be deadly to the human body. It is very difficult to dehydration and kidney toxicity react, they simply cease to exist and toxic substances are not removed from the body. This condition is called acute renal failure
Acute renal failure - causes and consequences
, Which is very difficult to treat, even in conditions of intensive care.
Parents should not give up on the direction of the hospital, if the background of vomiting and diarrhea in the child appears severe dry skin and mucous membranes (especially evident on chapped lips), and for several hours there was no urination. Help this child to recover water and salt exchange can only intravenous drip of special solutions. Otherwise, the condition can quickly worsen and the child can lose. According to the literature in the United States each year rotavirus sick more than a million children aged one to four years, of which killed up to 150 children.
At the same time, timely arrival of the child in the hospital is a guarantee of its recovery.
Feature rotavirus actions on the gastrointestinal tract is that it can cause a persistent infringement of digestion and absorption of food and the reduced secretion of intestinal enzymes. All this leads to the fact that changes the acidity of the intestinal contents, it becomes alkaline, which feels more comfortable conditionally pathogenic and pathogenic microflora, it starts to actively proliferate. Useful as microflora, which normally suppresses the development of opportunistic, in this case, by contrast, has difficulties in reproduction, since it is more accustomed to acidic environment.
Violation of the ratio between beneficial and pathogenic microflora is called dysbiosis. Dysbacteriosis - it is not a disease, opportunistic microorganisms still grow in the intestinal lumen, disrupting the process of digestion, but they do not penetrate the mucous membrane of the intestinal wall.
But indigestion (without the normal amount of useful microflora it may not be correct) is already causing poor circulation (and hence metabolism) in the intestinal wall and is only one step to the formation of the inflammatory process, ie colitis.
Dysbacteriosis the child may show decreased appetite, constant bloating
Bloating - if you are bursting inside
due to the large amount of gases (a consequence of improper digestion of food), paroxysmal pain during bowel (they arise from the muscle spasm of the intestine), nausea and impaired his chair. For dysbiosis is characterized by the alternation of diarrhea (in this chair might have a fetid smell), and constipation when the feces takes the form of solid pellets (sheep feces).
Dysbacteriosis requires a long persistent treatment. Appointed probiotics - drugs that contain live beneficial bacteria colonies - the natural inhabitants of the intestine. To these bacteria is well settled down in the gut and multiply rapidly, appointed prebiotics - drugs that contain "food" for the beneficial microflora.
How does the immune system after rotavirus infection
As after any infection, general immunity
Immunity - types and characteristics in children in adults
decreases and it takes time and effort to restore it. Specific immunity to rotavirus infection is not very resistant, so the child can get sick RVI many times, it is difficult to establish exactly how much because the RVI is often asymptomatic. Adults who are in the majority of antibodies to rotaviruses, which also indicates that the infection has been moved more than once. A very large percentage of detection antibody
Antibodies - "soldiers' immunity
to rotavirus in children and older age groups.
Several years ago in US children inoculated with a half months rotavirus vaccine, but was subsequently found that this leads to an increased incidence of intestinal obstruction in children, and the vaccine was prohibited. Today developed (including in our country) New vaccines against RVI, which are already in clinical trials.
RVI, like most viral infections, are currently not yet fully defeated.