Arbidol - contraindications: the danger is minimal

February 19, 2012

 arbidol contraindications
 Arbidol - it is a safe drug, in connection with which you can buy at a pharmacy without a prescription. Arbidol safety study was conducted on five kinds of animals (mice, rats, guinea pigs, rabbits, dogs). In addition, clinical trials were conducted and arbidol in humans suffering from viral infections.

 Arbidol - contraindications: the danger is minimal

How does arbidol

The main effect of Arbidol - antiviral, it prevents viruses from entering the body's cells. But, in addition, arbidol stimulates the production of virus-infected cells, special antiviral protein - interferon Interferon - protects against diseases of the new century?  Interferon - protects against diseases of the new century?
 Which protects against attack healthy cells infection. A healthy person's blood a little interferon, but when ingested viral infection amount it increases dramatically.

Arbidol helps the body cope with a bacterial infection, as it stimulates cell (increasing the number of phagocytes - cells that capture and digest pathogens) and humoral (antibody formation Antibodies - "soldiers' immunity  Antibodies - "soldiers' immunity
   to various infectious agents) Immunity Immunity - types and characteristics in children in adults  Immunity - types and characteristics in children in adults
 . Very often arbidol used in the treatment of chronic low-grade bacterial infection.

 Arbidol - contraindications: the danger is minimal

Results of laboratory and clinical tests

Laboratory tests arbidol conducted on a variety of mammalian species have established that it is a safe, low-toxic drug that has no adverse effects on the animals. Thus, the use of arbidol for six months, has not led to any changes in the body of animals.

It has been found that arbidol not cause changes in the mammalian blood biochemical parameters (i.e., metabolism) and tissue has no allergenic activity. It also does not cause malignant tumors, congenital malformations of offspring and negative effects on the central nervous system.

Investigation of oncogenic activity was carried out on animals in more than ten stages and lasted for more than two years. As a result, it was found that taking into arbidol and intraperitoneally administration does not increase the risk of malignant tumors. Moreover, it was found that arbidol able to prolong the life span of a sufficiently long time.

Laboratory tests were confirmed by clinical trials on almost 15 thousand patients of patients with viral diseases. After arbidol been approved for use, it took more than 20 years, and still has not been a single case of serious side effects with its use. Therefore arbidol widely used for both treatment and prophylaxis of viral infections in the general population.

The exception is pregnant women and nursing mothers, the purpose of which arbidol not contraindicated, but it is not recommended without the presence of vital evidence. In animal studies arbidol no negative influence on the development of the fetus and child bearing, but clinical trials in these patient population have not been conducted and therefore, even in spite of the convincing results of laboratory tests, one with certainty can not claim that arbidol not deny the negative actions in pregnant and breastfeeding women.

Sometimes arbidol still prescribed during pregnancy. This is done in the case where the intended benefits to the mother's body to be higher than the potential risks of using this drug for the body of the fetus. If there is a need for the appointment of arbidol woman who is breastfeeding, it is recommended during treatment to transfer the child to artificial feeding.

It was also found that arbidol does not affect the concentration and coordination of movements, so it can be administered to people involved in potentially hazardous activities, such as drivers of motor vehicles.

 Arbidol - contraindications: the danger is minimal

In some cases, you can not assign arbidol

First of all, arbidol not assigned when individual intolerance, which is fraught with the development of allergic reactions Allergic reactions: how to understand why you tickle in the throat  Allergic reactions: how to understand why you tickle in the throat
 . Allergic reactions can occur in many ways, and as a minor skin rash and a severe allergy (angioneurotic edema, anaphylactic shock). Allergic reactions are the only side effect of Arbidol.

Do not appoint arbidol well before the age of three years. If arbidol used in the recommended therapeutic doses, it does not overdose.

Thus, numerous laboratory and clinical trials, as well as the experience of arbidol for more than 20 years have convincingly proved safe, well tolerated, a high therapeutic and prophylactic efficacy arbidol.

Galina Romanenko

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  • arbidol

Arbidol - instruction: study the mechanism of action

February 19, 2012

 arbidol guide
 Arbidol - is an antiviral medicament with immunostimulating properties. Under the action of the drug in the body produces antiviral protein - interferon. In addition, it activates the cellular and humoral immunity and is therefore effective against bacterial infections.

 Arbidol - instruction: study the mechanism of action

Mechanism of action

Arbidol (active substance - метилфенилтиометил-диметиламинометил-гидроксиброминдол carboxylic acid ethyl ester) - domestic antiviral and immune-stimulating drug (manufacturer - the pharmaceutical company Pharmstandard), which is available in tablets and capsules (100 and 50 mg) for oral administration. The main mechanism of action of Arbidol is to stimulate the development of specific antiviral protein interferon. In addition, arbidol prevents the penetration of viruses in tissue cells, preventing contact and the fusion of the virus with the cell membrane. Sensitivity to arbidol exhibit influenza viruses A and B, as well as koronarovirusy causing SARS (severe acute respiratory syndrome).

Arbidol has a moderate immunostimulating effect by activating cellular and humoral immunity, thereby increasing the body's resistance is not only to the virus, but also to a bacterial infection. As a result, even if a person is ill some viral or bacterial infection, it is milder and no complications. As you know, after viral infections often exacerbated chronic infectious-inflammatory bacterial disease. In applying arbidol number of relapses is reduced.

Directly viral infections when used arbidol flow easier (reduces the symptoms of intoxication, the severity of catarrhal symptoms, shorten the length of the period of temperature rise), and do not give complications. Arbidol has no significant side effects when used in recommended doses. Arbidol also has antioxidant activity - eliminates toxic free radicals formed as a result of redox reactions, thus clearing the body.

Once in the gastrointestinal tract, arbidol absorbed in the gut wall and into the blood in first and then the organs and tissues. Then arbidol partially decomposed into products of metabolism in the liver and excreted in the urine. More than a third of arbidol excreted unchanged in the bile and feces.

 Arbidol - instruction: study the mechanism of action

Indications and contraindications

Indications for use arbidol are:

  • acute respiratory viral infections, including influenza A and B, SARS, complicated by inflammation of the bronchi and lungs;
  • rotavirus infection Rotavirus: favorable prognosis  Rotavirus: favorable prognosis
   in children older than three years;
  • often exacerbated by herpes infection;
  • decreased immunity Immunity - types and characteristics in children in adults  Immunity - types and characteristics in children in adults
  • chronic infectious and inflammatory diseases of the bronchi and lungs (in the complex treatment);
  • restoration of immunity and prevention of infectious complications after any surgical intervention.
  • Application arbidol contraindicated:
  • if you are hypersensitive to the drug;
  • under the age of three years.

The manufacturer has not provided data on the use of arbidol during pregnancy and nursing Breastfeeding - a personal choice  Breastfeeding - a personal choice
   breast, so during pregnancy it can be used only for health reasons and on doctor's orders. If the need arises in the appointment during lactation, it is better to time to interrupt breastfeeding. With careful preparation is indicated for liver and kidney diseases, which are accompanied by violation of their functions.

Arbidol has no negative effect on the central nervous system, so during his administration may carry out any operation, including driving a car.

Arbidol well tolerated, and almost no side effects (except allergic reactions) and overdose.

 Arbidol - instruction: study the mechanism of action

How to take arbidol

Arbidol taken orally before a meal. From prevention to adults and children over twelve years of age take 200 mg (two capsules or tablets of 100 mg or four tablets of 50 mg), children aged six to twelve years - 100 mg, three to six years - 50 mg reception. If you have contact with patients with influenza and other acute respiratory viral infections arbidol prescribed once a day for two weeks.

During the epidemic of influenza and other acute respiratory viral infections, as well as for the prevention of exacerbations of chronic bronchitis Bronchitis - protection if the body has malfunctioned  Bronchitis - protection if the body has malfunctioned
   and exacerbation of herpes in adults and children in the age arbidol appointed doses twice a week for three weeks.

Arbidol treatment of viral and bacterial infections appointed doctor.

Arbidol - domestic antiviral drug, which is now widely used to treat not only the virus, but bacterial infections.

Galina Romanenko

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  • arbidol