In the instructions, the manufacturer's gliatilin Italian pharmaceutical company Italfarmako no data on how the drug acts on children. It mentions only the possibility of the appointment of the drug for children with brain injuries and their consequences.
How does gliatilin
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in brain cells. But gliatilin basic action is that it improves the conduction of nerve impulses in the brain.
The principle of action of this drug is that if it enters the patient's blood it is decomposed into two substances are actively involved in the biochemical processes of brain cells, - choline and glycerophosphate. Choline is an additional source of formation in the body of acetylcholine - a neurotransmitter, which control the transmission of nerve impulses from cell to cell in the brain tissue. Glycerophosphate is a source material for the formation of phospholipids, which are indispensable for the existence of the membranes of nerve cells.
This action causes the nerve cells "alive", they improve metabolism
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and the ability to plastic transformation - that is, the ability to recover partially destroyed and create new links between them. Thus, when organic lesions in the brain (eg, after a traumatic brain injury), transmission of nerve impulses is bypassing the lesion, thereby compensating for the violations. This contributes to the rapid recovery of brain function.
It is believed that after a traumatic brain injury should be as soon as possible to appoint gliatilin. It is especially effective for severe traumatic brain injury with impaired consciousness.
In what diseases and conditions in children can be used gliatilin
Gliatilin has no age restrictions. At the same time, the instruction tells us little about its use in children. The instructions to gliatilin can be found only a small mention of the fact that the drug can be used in the complex treatment of traumatic brain injury (TBI) in children. Obviously, this is due to lack of clinical trials of this drug in children.
TBI injuries in children are common, while even a slight concussion of the brain can affect the entire subsequent period of child development. However, in children due to high compensatory possibilities of the body more often than in adults, there is a favorable outcome even severe head injury.
In young children, disturbance of consciousness at TBI are rare, usually a child becomes sluggish, lethargic, vomiting occurs. The most common head injuries received by children from three to seven years, with children more often than adults, there are damaged skull bones - this is due to structural features of the bones in children. Damage to the bones often leads to serious injury in children with disorders of consciousness.
Children with TBI appointed complex treatment, which in the absence of intracranial bleeding from the first day is recommended to include gliatilin.
Begin treatment with intravenous or intramuscular administration gliatilin, and then when the child's condition improved and he regains consciousness, go to the reception of its interior in the form of capsules. Apply gliatilin and during the rehabilitation period after a traumatic brain injury - it helps to restore the basic functions of the brain, including intelligence, memory, learning and acquiring new skills.
Contraindications, side effects and overdose
In accordance with the instructions contraindication for appointment gliatilin children is only heightened sensitivity to the body of the child components of this drug.
Side effects are mainly known gliatilin allergic reactions
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Which while taking the drug administration can take the form of an itchy rash or hives. Far more dangerous allergic reactions by parenteral (injection) administration of the drug. They can be heavy, up to anaphylactic shock.
Occasionally during treatment gliatilin
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nausea, but it does not require drug withdrawal, simply reduce the dose. Overdose gliatilin also manifested by nausea and usually is not dangerous - removal of the drug leads to the fact that all the unpleasant sensations are.
Gliatilin prescribed to children with brain injuries. In other diseases and conditions it is used much less frequently, as of today there is not much experience with this drug in children.
Galina Romanenko