Psoriasis - immune system alarm - Causes

December 18, 2013

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 Psoriasis causes


The most common normal (spotted) psoriasis - it is diagnosed in 80% of all cases of psoriasis, which manifests itself in the form of spotty rash, often convex and covered with silvery-white scales. Psoriatic spots often appear on the elbow, popliteal cavities, lower back and scalp, but can also appear on any other parts of the body.

Regardless of the type of psoriasis causes discomfort, as accompanied by severe pruritus, skin rash on the ground crack and bleed. In severe cases, itching and discomfort do not give a patient to sleep through the night, and the pain prevented deal with usual business day.

Psoriasis - a chronic disease (it is preserved for life) because the drug for its complete cure is not yet invented. In patients with psoriasis often occurs in remission for life. Reducing signs and symptoms of psoriasis The symptoms of psoriasis - a great variety  The symptoms of psoriasis - a great variety
   usually requires long-term treatment.

Treatment of psoriasis depends on the severity and type of disease. Sometimes psoriasis occurs so easily that the patient is not even aware of their condition. In some cases, psoriasis develops to such severity that psoriatic plagues cover the entire surface of the body. In such cases need urgent hospitalization. But these are extreme cases. Typically, most cases of psoriasis is between these two extremes.

Psoriasis does not distinguish between sex and affects equally to women and men. Recent studies have shown that the disease psoriasis may be associated with race and ethnicity - so Caucasians supposedly more vulnerable to disease psoriasis than blacks or Mongolians. Worldwide, psoriasis is most common in the Nordic countries and the Nordic countries. Much rarer is a disease found in Asia, Africa and even rarer.

Psoriasis can rightfully claim to be the oldest recorded skin disease. The first mention of it belong to 35 BC Some evidence indicates that psoriasis has been known up to this time. Nevertheless, until recently it has been known for very small.

Although scientists still do not know the exact cause of psoriasis, research significantly expanded our understanding of this disease.

An important breakthrough in this direction was outlined to the opening tsikloporina beneficial effect in patients with psoriasis who underwent kidney transplant. Since tsikloporin is a potent immunosuppressive drug, indicating its action on immunological causes of psoriasis Causes of psoriasis - It is not known  Causes of psoriasis - It is not known


The immune system

Today, scientists believe that the disease psoriasis is associated with the state of the immune system. This means that psoriasis may cause pathological signals the immune system. It is believed that psoriasis develops when immune system "tells" the body to enhance the reaction and accelerate the growth of new cells.

In normal skin cells grow old and die are rejected skin surface every 28 - 30 days. When the disease psoriasis, maturation and death of skin cells occurs in only 3-6 days, and then they come to the surface of the skin. Instead torn away, they accumulate on the surface in the form of ulcers.



Scientists have found genes which cause psoriasis. These genes determine the immune response of the organism and therefore may cause psoriasis or other diseases associated with the immune system, for example, rheumatoid arthritis Arthritis - a variety of forms and complications  Arthritis - a variety of forms and complications
   1 degree or diabetes. The probability of the disease psoriasis and other diseases associated with the immune system, especially diabetes or Crohn's disease, increases when the psoriasis sick relatives.


Family history

Some people in the family who have psoriasis patients. Never face the disease. According to the research, to work for "clockwork" family history, need some impetus. Stress, skin injuries, a strep infection, certain drugs, and sunburn can trigger the development of psoriasis.

Lekarstva- "provocateurs" - especially antimalarials, beta-blockers (drugs used in the treatment of hypertension and heart disease) and lithium. Dermatologists occasion to observe patients who developed psoriasis suddenly after taking these drugs, infection streptococcal infection silt under the influence of another trigger.


Impact on quality of life

All types of psoriasis of any severity invariably affect the quality of life of the patient. It is not easy to lead a normal life with a chronic skin disease.

Constant itching, soreness, cracked and bleeding skin - just a few symptoms of psoriasis, faced by all patients. Nail psoriasis is particularly painful - the patient is causing anguish simple action hands, for example, squeezing toothpaste Toothpastes - how to choose?  Toothpastes - how to choose?
   from the tube. One of the patients with psoriasis compared sensations with feelings of 'sunburn, which does not pass. "


Prospects for treatment

The emergence of a number of modern means of treatment, including the use of biological agents, can significantly reduce the severity of psoriasis in many patients and improve their quality of life.

Advances in the treatment of psoriasis - Modern Methods

December 16th, 2013

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 Modern methods of treatment of psoriasis

Current treatments for psoriasis

Current treatments for psoriasis are done by the new generation of drugs created using genetic engineering techniques. These are called biological therapies. These methods are aimed at certain segments of the inflammatory process, ie, the suppression of biologically active substances of cytokines, are actively involved in the inflammatory process.

This is a very effective treatment, which, moreover, gives a minimum of side effects. But these drugs are not only evidence but also contraindications to be considered by the attending physician. New drugs for the treatment of psoriasis - is efalizumab, thymodepressin, alefacept, and basiliximab (Simulect), infliximab, adalimumab, ustekinumab. All of them act selectively on different chains of inflammation.

And yet the best cure for psoriasis - is one that is best suited to this patient. Such means chosen physician individually and it does not necessarily have to be the most modern - an effective remedy for psoriasis should approach an individual patient as the key to the lock.


Physical therapy methods for the treatment of psoriasis

Current treatment regimens for psoriasis almost always involves the use of ultraviolet radiation (UVR) The waves of medium length (selective phototherapy) and wavelength A (photochemotherapy or PUVA therapy).

Selective phototherapy Phototherapy - restores vitality  Phototherapy - restores vitality
   - An effective way to treat psoriasis, it is carried out in a day, a course of treatment requires 20-40 treatments. PUVA therapy is performed with oral two hours before the test substance with photosensitizing properties to increase the skin's sensitivity to ultraviolet irradiation, and only after that the irradiation of the skin rays A. The frequency of procedures - in a day, the total number of procedures - from 15 to 30. PUVA Therapy is considered one of the most effective treatments for psoriasis.

Physiotherapy apparatus for the treatment of psoriasis is a fluorescent lamp erythema. It can also be a quartz lamp for the treatment of psoriasis and 60-watt germicidal lamp arc.

PUVA therapy is contraindicated if you are hypersensitive to the drugs, increased photosensitivity, acute gastro-intestinal diseases, diabetes Diabetes - threatening and incurable disease  Diabetes - threatening and incurable disease
 , Hyperthyroidism, hypertension, tuberculosis, pregnancy, any tumors, wasting, cataracts, severe diseases of internal organs, as well as children and patients older than 55 years.

There are also the latest methods of treatment of psoriasis, such as excimer laser system emitting a beam of high-intensity ultraviolet radiation, and for the treatment of moderate and severe psoriasis;

Equipment for treatment of psoriasis can have a laser basis. Laser treatment of psoriasis can be carried out helium neon and helium-cadmium lasers. Local influence of helium-neon laser at large psoriatic lesions resorption lesions occurred significantly faster in most patients.

Laser treatment of psoriasis - the most effective method of treatment. Besides simple as it is effective for psoriasis psoriasis nails Nail psoriasis - a difficult problem  Nail psoriasis - a difficult problem
 , Palmoplantar psoriasis, as well as severe forms of psoriasis, pustular psoriasis mainly Pustular psoriasis - a severe form of the disease  Pustular psoriasis - a severe form of the disease
   and psoriatic arthritis.


Psoriasis treatment during lactation

Psoriasis treatment during lactation should be carried out strictly on prescription. This can be used, for example, herbal drugs, has no toxic effects on the body. For example, dietary supplements of milk thistle oil has wound-healing, anti-inflammatory, analgesic, immunostimulant, restorative action.

In psoriasis, it may be applied topically in the form of application. On the affected skin is applied gauze soaked with oil and close the bandage and leave for a day or two. The course of treatment - two weeks.