Roaccutane - a drug for the treatment of severe, not treatable by other methods of acne Acne: facial trouble . Since acne is mainly young people, there are often questions about whether it is possible to combine the receiving Roaccutane alcohol. Guide said that isotretinoin should be taken with great care in chronic alcoholism. Why is that?

How does roakkutan

Active ingredient of Roaccutane is a synthetic analogue of vitamin A isotretinoin. In Roaccutane it is in a large dose. This allows the retard growth (proliferation) and differentiation of cells of the sebaceous duct, which accumulates in the fat (the more fat in the form of triglycerides in the blood, so this process is active). The maximum amount of fat accumulated in the most mature cells which burst and oil flows into the lumen of the duct.

Roaccutane causes not only suppression of the process, but also contributes to changing the chemical composition of sebum (it becomes less viscous) and dissolve dead cells (mixed with sebum, they obstruct the ducts of the sebaceous glands, and that contributed to the formation of acne).

Thus, the higher fat (triglyceride) in the blood, the more likely to develop acne. Contributes to the amount of triglycerides in the blood of many factors. But especially effectively operates in the direction of alcohol. A large amount of triglycerides in blood contributes to the development of fatty changes in the liver.

A feature of retinoids is the fact that they also accumulate in the liver cells, disrupting their work, and long-term use at high doses and destroying. One of the side effects of Roaccutane first is transient, and then persistent abnormal liver function with the development of toxic hepatitis.

With prolonged use of Roaccutane possible the development of pancreatitis.

Features of fat metabolism in chronic alcoholism

The systematic use of alcohol in the blood always contains a higher amount of triglycerides. Alcohol promotes the excretion of fat from adipose tissue, increased amounts of fats in the blood, while simultaneously decreasing the intake of fat muscle cells.

This leads to the fact that the fat begins to accumulate in the liver. Its active capture liver cells, this leads to a fatty degeneration of the body - of fatty liver. In addition, alcohol has a direct toxic effect en liver cells (hepatocytes), destroying them. This is a very dangerous condition, which helps reduce liver function. Over time, the adipose tissue may be replaced with the formation of connective alcoholic cirrhosis - alcohol stimulates the development of connective tissue.

Elevated levels of triglycerides in the blood can cause serious diseases such as acute pancreatitis. It is especially dangerous to mix alcohol with fatty foods. Admission fatty food stimulates the release of a large number of pancreatic juice. Alcohol and its decay products violate the pancreatic duct patency Diabetes and pancreas - the things you need to know . This leads to the fact that pancreatic juice begins to digest the tissue of the prostate. The disease is very dangerous and often ends with the death of the patient.

What can cause the combination of alcohol and Roaccutane

The instructions to the manufacturer of Roaccutane (Swiss pharmaceutical company F. Hoffmann-La Roche Ltd) indicates that in chronic alcoholism to the appointment of this preparation should be approached with caution. About the use of Roaccutane with alcohol does not say anything. However, knowing the mechanism of action of Roaccutane and alcohol can make a number of conclusions.

It is known that isotretinoin and alcohol have hepatotoxic properties. They can adversely affect (isotretinoin), and even to destroy (alcohol) hepatocytes. Depending on the initial state of the liver, including the hereditary characteristics of this body, which may have different consequences. If the liver is healthy (and this few can know for sure), the use of alcohol during treatment Roaccutane Roaccutane - a drug for the treatment of severe acne   will not cause significant violations.

If liver function is impaired (eg, chronic alcoholism), this combination may result in a heavy defeat - toxic hepatitis Toxic hepatitis - the impact of harmful substances on the liver   and necrosis.

Large enough and the risk of acute pancreatitis, again it increases in chronic alcoholism.

Roaccutane - a drug, which has many side effects, including from liver and pancreas. Strengthen them, taking alcohol, at least unwise.

Galina Romanenko

Shampoo for psoriasis should be selected individually, and as produced myriad medical and preventive treatment of psoriasis shampoo, perhaps to choose the most appropriate means (and preferably several means, as they should be alternated) will have to spend a lot of time. The same applies to shower gels and soap for psoriasis - their selection should be individualized.

How to wash my hair in psoriasis

Scalp psoriasis is very sensitive, so it needs special care. In psoriasis used as soft neutral shampoos or shampoos, which include a variety of drugs.

Treatment of psoriasis shampoos contain tar (birch, coal, juniper, pine). All kinds of tar soften the scalp and inhibit the development of psoriatic lesions. Nevertheless, should choose their own, individual tar shampoo as important not only tar and adjuvants are in the shampoo - they can cause increased dryness, itching and so on. To shampoos with tar include Friderm Tar, Algopiks (with juniper tar), Tana tar, shampoo grandmother Agafia "for bath Tar" tar shampoo Terva Shampoo Tjarscampo (Finnish pine tar) and so on.

Shampoo of psoriasis may also contain an antifungal agent as psoriasis of the scalp is much dandruff Dandruff: where it comes from, and what to do Caused by a fungal infection. Therefore, sometimes the head should be washed with shampoo and antifungal effect: Nizoralom, Ketozoralom and so on.

Pharmaceutical company Schering-Plough (USA) has developed an effective shampoo for psoriasis of the scalp and prevent its relapse - Friderm TAR, which helps to slow down and inhibition of proliferation of epidermal cells, as well as astringent and antifungal activity. The use of this medicinal shampoo cleanses the scalp from the fat and dandruff.

Shampoo Friderm TAR after shaking applied to wet hair for five minutes, then wash off with water. The second time is applied as a shampoo for five minutes and re-rinse head. Procedures should be carried out twice a week course of treatment - two to four months.

The same companies manufacture basic shampoo for psoriasis on the head Psoriasis on the head - how to deal with illness   Friderm balance in the composition of which contains neutral detergents that achieve and maintain a constant pH level of the skin close to normal. This ensures a good cleaning and degreasing effect soft even with frequent shampooing.

Shower gel for psoriasis

It is of great importance and shower gel for psoriasis. Daily shower gels should be neutral, should not contain skin-irritating substances.

Also produced gels for the treatment of psoriasis. For example, a gel for psoriasis Psorilom (shower gel, Alcoy-Holding, Russia). It is recommended for daily care of the problem, prone to itching and flaking skin. In the gel consists of birch tar, fungus extract and humic extract of sapropel. Psorilom has antipruritic, anti-inflammatory, antiseptic and antifungal activity. It does not irritate even the most sensitive skin Sensitive skin: causes and care That allows you to use the gel as often as you need it. It is recommended for daily care for problem skin of the body, including psoriasis.

A small amount of gel should be applied to wet a soft sponge, lather, lather your skin and rinse thoroughly with water. After using the shower gel, it is advisable to put on your skin is still damp spray or body lotion Psorilom. Gel leaves no odor of tar on the skin, non-irritating, it does not contain dyes and perfumes. It is compatible with any means for hygiene and skin treatments.

In psoriasis can also use shower gels Sesderma, Topikrem and others - the selection of the gel should be carried out individually.

Soap from psoriasis

Most often, of course, using tar soap: Neva Cosmetics, Tan, simply tar soap from different manufacturers. Tar soap does not dry the skin, soothes itching, anti-inflammatory and antibacterial action.

During an exacerbation of psoriasis skin is particularly sensitive, and some patients can not tolerate even tar soap. Such patients recommend the use of such neutral soaps hypoallergenic effect as baby soap without additives.

In psoriasis fit well: the black soap for baths Sauna and health: the benefits and harms of bath procedures   Siberian from Agafya, castile soap, soap Sage Cleon, sulfur soap, sulsenovoe soap, Styx with goat milk and calendula (Austria), Soap Alverde with grapefruit and lemon (Germany), soap and other Psora.

From conventional cosmetic patients with psoriasis most suitable cream Nivea and Dove soap.

The selection of shampoos, shower gels and soaps for psoriasis should be individualized.

Galina Romanenko