The cause of stomach ulcers is usually infection caused by - the bacterium H. pylori. For the treatment of gastric ulcers usually requires receiving rate kislotoponizhayuschih preparations which lasts four to eight weeks. Furthermore, within one week of antibiotics required - this usually prevents recurrence of ulcers. Anti-inflammatory drugs used for the treatment of disorders such as arthritis Arthritis - a variety of forms and complications Sometimes become a cause of stomach ulcers. If you need to continue taking anti-inflammatory drugs, may require a long course of reception kislotoponizhayuschih drugs.

Causes

Normally, the stomach produces acid to digest food and kill bacteria. This acid is corrosive so some cells of the inner lining of the stomach and duodenum produce a natural mucus barrier which protects the wall of the stomach and duodenum. There is a balance between the amount of acid which produces stomach and mucous barrier protective properties. An ulcer develops when the balance is disrupted, and the acid damages the walls of the stomach and duodenum. This can happen for several reasons.

Helicobacter pylori

Infection with Helicobacter pylori, the cause of about 8 out of 10 cases of gastric ulcers. Experts estimate that about a quarter of the world's population at some period of life infected with H. pylori. After infection, if left untreated, the infection remains in the body throughout life. For many people, it does not cause any problems, and the bacteria just live harmlessly walls of the stomach and duodenum. However, in some cases the bacteria cause inflammation of the lining of the stomach and duodenum. This leads to the destruction of the mucous barrier protective (and sometimes to increase the production of gastric acid), because of which the formed and gastric ulcer.

Anti-inflammatory drugs - including aspirin

Anti-inflammatory drugs, or NSAIDs, such as aspirin, ibuprofen Ibuprofen: anti-inflammatory drug Diclofenac Diclofenac - relieve inflammation and pain And that further, take to relieve the symptoms of colds and flu, relieving headaches and arthritis, muscle pain, and other violations. Aspirin is sometimes taken to prevent blood clots. These drugs can adversely affect the gastric mucosal barrier and cause the formation of ulcers. It is assumed that the anti-inflammatory drugs cause two of 10 cases of gastric ulcer.

Other causes and factors

Other causes of stomach ulcers are relatively rare. For example, certain viral infections can cause stomach ulcers. Crohn's disease may lead to the development of stomach ulcers and other disorders of the intestine. Sometimes, stomach cancer causes symptoms similar to the symptoms of stomach ulcers. Although gastric cancer is rare, it is one of the diseases that should be excluded in the diagnosis of gastric ulcers.

Symptoms

The most common symptom of stomach ulcer is pain in the upper abdomen. Kislotoponizhayuschie drugs to help cope with the symptoms. Sometimes the pain gets worse after eating certain foods.

Other symptoms of stomach ulcer: bloating, vomiting, and malaise.

Complications

Gastric ulcer can cause very serious complications, such as:

Bleeding from ulcers. The intensity of bleeding can range from very mild to severe and life-threatening.

Perforation of the stomach wall. Untreated ulcers can lead to perforation, i.e. the formation of a hole in the stomach wall. Usually. This condition is accompanied by severe pain and requires immediate medical care.

Diagnostics

Endoscopy - a test which is used to confirm the presence of gastric ulcers in a patient. The doctor examines the stomach wall using a small camera, which is on the end of a thin, long and flexible tubing - a device called an endoscope.

If using endoscopy detected a stomach ulcer, an analysis on the H. Pylori. If the result of analyzes, these bacteria are considered to be the cause of stomach ulcers.

To eliminate stomach cancer Stomach cancer: genetics and lifestyle   biopsy - a small sample of tissue sampling during the biopsy, which is then sent to a lab for analysis.

Ersefuril - instructions for use of the drug's manufacturer - the pharmaceutical company Sanofi (France). It details the mechanism of action, indications and contraindications for its use, possible side effects and so on.

The mechanism of action ersefuril

Ersefuril - it is an antibacterial drug broad spectrum to treat infections of the gastrointestinal tract, the active substance of which is nifuroxazide belonging to the group of nitrofurans. Produced ersefuril capsules for oral use, each containing 200 mg nifuroxazide in a 4% suspension in 5 ml which contained 200 mg as nifuroxazide. Nifuroxazide is also the active substance of such drugs as diastat, Enterofuril Enterofuril - help with the intestinal infection   and nifuroxazide.

Auxiliaries ersefuril capsules are corn starch, sucrose and magnesium stearate. The composition of the capsule comprises gelatin, titanium dioxide, dye - yellow iron oxide.

When used in recommended doses ersefuril has a bacteriostatic effect (suppress the livelihoods of pathogens intestinal infections), high doses - bactericidal (kills these pathogens). The mechanism of action associated with suppression ersefuril some redox enzyme reactions in the cells of pathogens.

Sensitivity to ersefurilu Ersefuril - to cope with a slight diarrhea of ​​infectious origin   shows the majority of microorganisms that cause intestinal infections: Staphylococcus, Streptococcus, Clostridium, E. coli, salmonella Salmonella: unknown facts , Shigella, enterobacteria Yersinia and Vibrio cholerae even. Immune to ersefurilu Klebsiella, some strains of Proteus and some other agents of intestinal infections. A feature ersefuril (like all nitrofurans) is that they have not developed resistance (immunity) agents of intestinal infections and inhibits the development of intestinal microflora.

Ersefuril acts only locally in the gut and practically not absorbed into the blood and does not have a general (systemic) action.

Indications and contraindications for use ersefuril

The indications for use are ersefuril diarrhea of ​​infectious origin caused by susceptible pathogens to ersefurilu. Ersefuril it makes sense to apply only in the case where the infectious process occurs without fever or worsening of general condition. Simultaneously with the reception ersefuril need to replenish lost fluids in the form of abundant drinking or saline solutions prepared based drugs (eg, rehydron).

Do not use this ersefuril hypersensitivity to nitrofuran derivatives or any of the excipients of the drug, fructose intolerance, a syndrome of glucose-galactose malabsorption or failure sucrase and isomaltase (due to the presence in the preparation of sucrose) and during pregnancy (no clinical experience with ersefuril in pregnant ). Capsules ersefuril not approved for use in children under six years old, the slurry - children under the age of one month. In some countries, the suspension is not allowed for the use of children under the age of two years.

Breastfeeding is not a contraindication for use ersefuril as a short course of treatment.

Side effects and possible overdose

Ersefuril very well tolerated by both adults and children. Drug overdose is practically impossible, since 99% of it does not get into the blood and has no systemic effects.

But even 1% of the substance has got into the blood enough to cause an allergic reaction. Allergic reactions while taking ersefuril may take the form of various kinds of itchy allergic rash, quickly appearing and disappearing hives (rash of blisters run together), angioedema (angioedema subcutaneous tissue, which can lead to respiratory failure). The most severe allergic reaction to the reception ersefuril may be anaphylactic shock, which is quite rare and is accompanied by a sharp decrease in blood pressure Blood pressure - dangerous if his swing? , Collapse and loss sznaniya. If you suspect an allergic reaction ersefuril intake should be discontinued.

Ersefuril - a drug nitrofuran series, which is used for the treatment of mild intestinal infections without disrupting the overall condition of the patient. For treatment of more severe intestinal infections, antibiotics are used, providing general (systemic) action.

Galina Romanenko