Duspatalin - is an effective and non-toxic antispasmodic drug. But it is available only in dosage forms for oral administration, and acute pancreatitis or severe exacerbation of chronic pancreatitis accompanied by severe abdominal pain and vomiting, antispasmodics in this state can only be applied by injection.

Pancreatitis - he begins and proceeds

Pancreatitis - is an aseptic (without infection), inflammation of the pancreas. The disease may be acute or chronic. Acute pancreatitis - it does not actually inflammation and destruction of the pancreatic cells activated by enzymes of pancreatic juice. This can occur as a result of intensive stimulation of the prostate (e.g., with alcohol), and under occlusion gland excretory ducts. The result is a self-digestion of the pancreas, which is accompanied by severe pain, vomiting, often fall in blood pressure Blood pressure - dangerous if his swing?   pain and shock.

Chronic pancreatitis is characterized by alternating relapse and remission. During exacerbations occur the same processes as in acute pancreatitis, but of lesser intensity. Each exacerbation dies a certain amount of pancreatic cells Diabetes and pancreas - the things you need to know Instead of which grows connective tissue, resulting in decreased pancreatic function.

Treatment of acute pancreatitis and exacerbation of chronic pancreatitis is the maximum reduction in pancreatic function, reducing its swelling Prevention and treatment of edema - it is important to understand the root cause , Removing a spasm of excretory ducts and Pain Therapy. For spasmolysis excretory ducts of the pancreas and the sphincter of Oddi (circular muscles in the discharge hole total pancreatic duct and bile) antispasmodics administered by injection. Since Duspatalin is available only in the form of dosage forms for oral administration, in severe acute process, it can not be applied.

In what cases can be applied Duspatalin pancreatitis

Duspatalin (active substance - mebeverin) - is an antispasmodic drug myotropic direct action, that is, it acts directly on the smooth muscles of internal organs, mainly the digestive system. Duspatalin produced in two dosage forms for oral administration: in the form of coated tablets (each tablet contains 135 mg of mebeverine) and long-acting capsules (each capsule contains 200 mg of mebeverine).

When a moderate course of exacerbation of chronic pancreatitis, when there is a very severe pain and vomiting as an antispasmodic can be assigned Duspatalin. This drug effectively relieves spasms of smooth muscles of the pancreatic ducts. But the main advantage Duspatalin is that it selectively acts on the sphincter of Oddi, removing spasm and facilitating the excretion of bile and pancreatic juice into the duodenum. This fully motor activity of smooth muscle of the duodenum (peristalsis) is not suppressed, which improves the outflow of pancreatic juice.

Apply Duspatalin in chronic pancreatitis and exacerbation is a part of complex anti-treatment. Removing spasm of smooth muscles of the excretory ducts of the pancreas, and the timely removal of stasis of pancreatic juice prevents the development of exacerbations of the disease and reduces the risk of developing persistent dysfunction of the body.

In some cases, Duspatalin contraindicated

Duspatalin not be used if you are hypersensitive its components the body of the patient - in this case, the allergic and non-allergic reactions. Manufacturers (international pharmaceutical company Abbott) does not recommend the use of Duspatalin children under 18 years of age due to the fact that clinical trials have not been conducted on this cohort of patients. However, today it has experience with this antispasmodic children, including chronic pancreatitis.

Clinical trials have not been carried out as a nursing mothers and pregnant women, therefore the use of Duspatalin during feeding baby Breastfeeding - a personal choice   feeding is not recommended. If the use of this drug is vitally important to be temporarily interrupt breastfeeding.

During pregnancy Duspatalin capsules has no absolute contraindications for health it can be administered, while Duspatalin tablets for use during pregnancy is not recommended.

Duspatalin used in the treatment of pancreatitis, but not always and only on prescription.

Galina Romanenko

Diffuse changes of the pancreas - a conclusion in some cases completes the description of the changes that the doctor found the ultrasound diagnosis in this organ. How braving such a conclusion, and what it says to the patient, as a rule, it is not clear and it is often frightening.

Pancreas and its main functions

The pancreas is located on the back wall of the abdominal cavity and partly hidden by the front of her stomach. It recovered the body, head and tail, smoothly, without borders, into each other. Functions of the pancreas in Diabetes and pancreas - the things you need to know   two and two main. The main part of the tissue of the pancreas produces pancreatic juice, which is involved in the digestion of food - is exocrine function. But in the pancreas there is another glandular tissue - the so-called islets of Langerhans, which secrete insulin The principles of action of insulin - the science of saving lives   - A hormone that promotes the absorption of glucose Glucose: The energy source   fabrics - This function refers to the internal secretion.

Digestive juice is collected in a single duct which is connected to the common bile duct (it departs from the gallbladder) and opens in the duodenum. Thus, the pancreas is associated intimately with the liver and the biliary system, liver diseases and all necessarily reflected on the pancreas and conversely.

What is a "diffuse changes of the pancreas"

Diffuse changes of the pancreas - it is not a diagnosis, but the result of ultrasound (US). The word "diffuse" means that the change is uniformly distributed throughout the body. Such changes in the ultrasound can be in many organs. First of all, such a conclusion says that of the pancreas have small areas changes, which are called focal (patchy change can be, for example, of a tumor or stones).

During ultrasound that the normal pancreas normally homogeneous. In various diseases in the US, you can see it increase, decrease, increase or lower density and focal changes.

But the doctor ultrasound necessarily looking status of all of the digestive system, because the underlying illness may not be in the pancreas, and, for example, in the liver or biliary tract. In the pancreas, in this case, you can see the so-called reactive (a reaction to the disease of another body) changes.

In order to clarify, for example, why the pancreas is diffusely sealed, the doctor still need more research. First of all, blood chemistry by which to judge the function of the pancreas and liver. We need also a common blood test that detects, for example, signs of inflammation. In order to clarify the condition of the common excretory duct of the pancreas and biliary tract endoscopy of the duodenum during which the endoscopist may well consider it the mucosa at the confluence of the duct.

The data from all studies analyzing the therapist or the gastroenterologist, and only then sets a final diagnosis.

What diffuse changes can be detected in the pancreas

The pancreas can be revealed diffuse changes of a different nature:

• diffuse decrease in the density of tissue, decreased echogenicity (ability of a fabric to reflect the sound) with larger pancreas; such changes characteristic of acute pancreatitis, which occurs in violation of the outflow of digestive juices from the pancreas; in this case, the digestive juice begins to digest pancreatic tissue, it swells and increases in volume;
• diffuse density decrease tissue echogenicity reduction at normal size pancreas; These changes are similar to chronic pancreatitis, which occurs in violation of the digestion of fatty foods; excretory duct of the pancreas may be crimped;
• diffuse increase in echogenicity in normal amounts of the pancreas can talk about lipomatosis Lipomatosis - how dangerous is the disease   pancreas - the partial replacement of its fat tissues; disease sometimes arises in elderly patients with diabetes mellitus;
• diffuse changes of the pancreas with increased echogenicity and increase in density under normal or reduce the size of the pancreas; such changes are characteristic of fibrosis of the pancreas - the replacement of its tissue connective tissue that occurs when inflammation of the pancreas, or metabolic disorders.

Diffuse changes in the pancreas are irrelevant to the doctor only with the rest of the results of examination of the patient, as together they allow a correct diagnosis.

Galina Romanenko