Pyrantel - contraindications should be considered necessarily

May 20, 2012

 pyrantel contraindications
 Pyrantel - worming drug is a drug that has a high efficiency combined with a low toxicity. It has very few side effects compared with other anthelmintics drugs, and therefore few contraindications.

 Pyrantel - contraindications should be considered necessarily

Pyrantel and pregnancy

Pyrantel is fairly safe drug. In laboratory studies did not reveal any adverse effects of the drug on the fetus - not teratogenic (ability to cause malformations in the fetus) or embryotoxic - direct toxic effects on the fetus. However, pyrantel are not allowed to be used during pregnancy, since the position of clinical trials of the drug in pregnant women were not conducted.

Pregnancy - a special state, during which anyone, even the most insignificant impact may be fatal. Pyrantel basically acts in the intestine, with more than half of the dose comes from the feces unchanged. Part of the drug is absorbed into the bloodstream, and may cause the overall impact on the body. How will it affect the body pregnant woman and the fetus - no one knows. Rather, the general toxic action of this drug does not have, but maybe it relaxing effect on the muscles, which during pregnancy is not desirable.

 Pyrantel - contraindications should be considered necessarily

Pyrantel and breast-feeding

During breastfeeding take pyrantel also undesirable, as part of the drug is absorbed into the blood and can be released from their mother's milk. How much it stands is not known, so it is not necessary to apply it.

But pyrantel - a drug, which is applied from one to three consecutive days (depending on what is identified helminths). At this time it is really to interrupt breastfeeding, and then, after the end of treatment, feeding resumed. Today is available a sufficient number of infant formulas Dairy mixture - selection of useful power  Dairy mixture - selection of useful power
   for breastfeeding Breastfeeding - a personal choice  Breastfeeding - a personal choice
 So that when necessary treatment can replace breast milk mixture. And that breast milk is lost, it can express.

 Pyrantel - contraindications should be considered necessarily

Pyrantel and myasthenia gravis

Myasthenia gravis - a genetic disorder that is characterized by impaired transmission of nerve impulses undertaken by the neurotransmitter acetylcholine. As a result of complex mechanisms (including an excess of enzymes that destroy acetylcholine and autoimmune processes - allergy own tissues) does the transmission of nerve impulses from the brain to the muscles. This leads to the gradual formation of the growing weakness of the skeletal muscles.

The symptom is fatigue, which takes place after the holidays. Can develop a variety of disorders of the eye muscles, the muscles, the ongoing process of swallowing and breathing. Especially dangerous is the involvement of the respiratory muscles - it can cause the patient's death by suffocation.

Patients with myasthenia gravis Myasthenia gravis - not to be confused with chronic fatigue  Myasthenia gravis - not to be confused with chronic fatigue
   not allowed to take any drugs without a prescription. Especially dangerous drugs that can somehow affect the skeletal muscles. Pyrantel causes paralysis of the neuromuscular apparatus round helminths, ie can have some slight impact on human skeletal muscle. That is why it is contraindicated in infants.

 Pyrantel - contraindications should be considered necessarily

Pyrantel and liver disease

Pyrantel is contraindicated in diseases of the liver, which are accompanied by violation of its functions. When the body of the main part of the drug acts directly in the intestine, and then excreted in the faeces. But part of pyrantel Pyrantel: a means to combat intestinal parasites  Pyrantel: a means to combat intestinal parasites
   yet it absorbed into the blood after some time and enters the liver, where decomposed into products of metabolism, and then excreted in urine.

By reducing liver function pyrantel will slowly decay, and it is possible accumulation in the body in large amounts, especially if the drug is taken for several days. Of course, the risk is negligible, as pyrantel often taken a one-off. But nowhere in the manual does not specify whether pyrantel has a negative effect on the liver - this fact also should be considered.

 Pyrantel - contraindications should be considered necessarily

Pyrantel in case of hypersensitivity to it the body

Increased sensitivity to a particular drug may be manifested in the form of non-allergic and allergic reactions. These reactions are similar, despite the fact that they have a different mechanism of occurrence. If any form of hypersensitivity to a particular substance, it can not be used.

Pyrantel - it is non-toxic and fairly safe drug, but to take into account contraindications when it is used it is necessary.

Galina Romanenko


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  • pyrantel

Ranitidine - help in the prevention of relapse of peptic ulcer

April 8, 2013

 ranitidine
 Ranitidine - a drug, which inhibits gastric acid secretion and reduces its acidity. It is used by a doctor for diseases of the gastrointestinal tract associated with acidity. Independently take this drug should not be - it has side effects and contraindications.

 Ranitidine - help in the prevention of relapse of peptic ulcer

Medications - blockers H2-histamine receptors

Blockers H2-histamine receptors prevent ingress of histamine on his own receptors located on cells of the gastric mucosa - they just take place on the histamine receptors. Since the action of histamine on H2 receptors stimulates the secretion of gastric acid and hydrochloric acid under action of H2-blockers, histamine receptors, these indicators are reduced.

Preparations in this series for a long time and actively suppress the secretion and gastric acidity, both in daytime and at night, relieve heartburn and abdominal pain Abdominal pain: Types and Symptoms  Abdominal pain: Types and Symptoms
 . That is why they are widely used in the treatment of diseases such as chronic gastritis with increased secretion, peptic ulcer and duodenal ulcers, reflux esophagitis, and so on.

 Ranitidine - help in the prevention of relapse of peptic ulcer

Features of action of ranitidine

Ranitidine - a drug belonging to the group of H2 blockers histamine receptors, the second generation. It has all the positive properties of this group of drugs, reduces the activity of the enzyme to digest proteins pepsin stimulates healing of ulcers on the walls of the upper gastrointestinal tract, improves skin tone of the lower esophageal sphincter (this prevents acidic stomach contents into the esophagus), suppresses the formation of ulcer process stomach and duodenum under the influence of stress and drugs (eg, NSAIDs - diclofenac Diclofenac - relieve inflammation and pain  Diclofenac - relieve inflammation and pain
 , Indomethacin, and others), relieves heartburn and pain caused by ulcerative process.

Ranitidine not affect the operation of the pancreas, the motor activity of the duodenum and the stomach emptying time. The efficacy and duration of action of ranitidine is much higher than the figures of the first drug of this series - cimetidine. Side effects from ranitidine also less pronounced than that of cimetidine, and when properly used in the recommended doses occur very rarely.

 Ranitidine - help in the prevention of relapse of peptic ulcer

Which diseases prescribed ranitidine

Since the action of ranitidine is mainly due to the suppression of gastric secretion, it is widely prescribed for chronic gastritis with increased secretion, gastric ulcer and duodenal ulcer. It is part of an integrated treatment of disease recurrence, as well as in the anti-treatment, which is carried out in such patients in spring and autumn.

It is impossible to imagine without ranitidine treatment of reflux oesophagitis - inflammation of the esophagus associated with regular throwing into the esophagus acidic stomach contents. Reflux esophagitis can occur very hard, with ulceration and even perforation of the esophagus wall. Ranitidine is able to significantly reduce the risk of complications of the disease.

Apply ranitidine as in benign tumors (adenomas) of the pancreas Diabetes and pancreas - the things you need to know  Diabetes and pancreas - the things you need to know
 That produce gastrin hormone stimulating gastric acid secretion and hydrochloric acid. In the stomach, the duodenum and the early jejunum may form numerous nonhealing ulcers (Zollinger-Ellison syndrome).

Appointment of ranitidine ulcerative processes of the gastrointestinal tract associated with increased acidity of gastric juice is able to prevent the development of complications - bleeding and perforation of the wall of the gastrointestinal tract.

 Ranitidine - help in the prevention of relapse of peptic ulcer

Contraindications

This drug is contraindicated in case of hypersensitivity of the patient to its components, pregnancy, lactation, under the age of 12 years. Manufacturers ranitidine is recommended with caution, he was appointed in the human liver and kidney (recommended individually select such patients dose), as well as liver diseases and related disorders of brain function.

 Ranitidine - help in the prevention of relapse of peptic ulcer

What side effects may give ranitidine

Side effects with ranitidine may be many. That is why the drug can be purchased at the pharmacy only by prescription, which takes into account the indications and contraindications for its use.

Side effects can be the part of the digestive system, nervous, endocrine and cardiovascular systems, sensory organs, blood, musculoskeletal system. Allergic reactions Allergic reactions: how to understand why you tickle in the throat  Allergic reactions: how to understand why you tickle in the throat
 , Alopecia, and so on.

Ranitidine - is an effective drug, but it has to be taken only on prescription.

Galina Romanenko


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  • ranitidine




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