Ranitidine - a drug, which inhibits gastric acid secretion and reduces its acidity. It is used by a doctor for diseases of the gastrointestinal tract associated with acidity. Independently take this drug should not be - it has side effects and contraindications.
Medications - blockers H2-histamine receptors
Blockers H2-histamine receptors prevent ingress of histamine on his own receptors located on cells of the gastric mucosa - they just take place on the histamine receptors. Since the action of histamine on H2 receptors stimulates the secretion of gastric acid and hydrochloric acid under action of H2-blockers, histamine receptors, these indicators are reduced.
Preparations in this series for a long time and actively suppress the secretion and gastric acidity, both in daytime and at night, relieve heartburn and abdominal pain
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. That is why they are widely used in the treatment of diseases such as chronic gastritis with increased secretion, peptic ulcer and duodenal ulcers, reflux esophagitis, and so on.
Features of action of ranitidine
Ranitidine - a drug belonging to the group of H2 blockers histamine receptors, the second generation. It has all the positive properties of this group of drugs, reduces the activity of the enzyme to digest proteins pepsin stimulates healing of ulcers on the walls of the upper gastrointestinal tract, improves skin tone of the lower esophageal sphincter (this prevents acidic stomach contents into the esophagus), suppresses the formation of ulcer process stomach and duodenum under the influence of stress and drugs (eg, NSAIDs - diclofenac
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, Indomethacin, and others), relieves heartburn and pain caused by ulcerative process.
Ranitidine not affect the operation of the pancreas, the motor activity of the duodenum and the stomach emptying time. The efficacy and duration of action of ranitidine is much higher than the figures of the first drug of this series - cimetidine. Side effects from ranitidine also less pronounced than that of cimetidine, and when properly used in the recommended doses occur very rarely.
Which diseases prescribed ranitidine
Since the action of ranitidine is mainly due to the suppression of gastric secretion, it is widely prescribed for chronic gastritis with increased secretion, gastric ulcer and duodenal ulcer. It is part of an integrated treatment of disease recurrence, as well as in the anti-treatment, which is carried out in such patients in spring and autumn.
It is impossible to imagine without ranitidine treatment of reflux oesophagitis - inflammation of the esophagus associated with regular throwing into the esophagus acidic stomach contents. Reflux esophagitis can occur very hard, with ulceration and even perforation of the esophagus wall. Ranitidine is able to significantly reduce the risk of complications of the disease.
Apply ranitidine as in benign tumors (adenomas) of the pancreas
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That produce gastrin hormone stimulating gastric acid secretion and hydrochloric acid. In the stomach, the duodenum and the early jejunum may form numerous nonhealing ulcers (Zollinger-Ellison syndrome).
Appointment of ranitidine ulcerative processes of the gastrointestinal tract associated with increased acidity of gastric juice is able to prevent the development of complications - bleeding and perforation of the wall of the gastrointestinal tract.
This drug is contraindicated in case of hypersensitivity of the patient to its components, pregnancy, lactation, under the age of 12 years. Manufacturers ranitidine is recommended with caution, he was appointed in the human liver and kidney (recommended individually select such patients dose), as well as liver diseases and related disorders of brain function.
What side effects may give ranitidine
Side effects with ranitidine may be many. That is why the drug can be purchased at the pharmacy only by prescription, which takes into account the indications and contraindications for its use.
Side effects can be the part of the digestive system, nervous, endocrine and cardiovascular systems, sensory organs, blood, musculoskeletal system. Allergic reactions
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, Alopecia, and so on.
Ranitidine - is an effective drug, but it has to be taken only on prescription.