Ranitidine is generally well tolerated. However, this drug can produce many side effects. Therefore, it can not appoint all patients. Some patients, he was appointed individually selected dose. All of this is able to take into account only the doctor.

Therapeutic effects of ranitidine

Therapeutic effects are as ranitidine suppressing stimulating effect of histamine on gastric glands that produce gastric juice and hydrochloric acid. This leads to a reduction of gastric acid secretion and reduce its acidity. Simultaneously ranitidine helps restore the cells of the gastric mucosa, whose function is disturbed by the high concentrations of hydrochloric acid.

This action allows you to assign ranitidine in many diseases of the gastrointestinal tract associated with increased secretion of gastric juice.

Side effects

Ranitidine have many side effects, but it does not mean that they always appear. Basically, this drug was well tolerated when properly administered. Sometimes prolonged use of the drug in individually selected doctor high doses does not cause side effects. However, the side effects occur and should be disregarded.

So, from the gastrointestinal tract while taking ranitidine may experience nausea, vomiting, dry mouth, constipation or diarrhea (sometimes they follow each other), pain in the upper abdomen. They can react to receiving ranitidine and other digestive organs: in rare cases develop inflammation of the liver and pancreas Diabetes and pancreas - the things you need to know   (acute hepatitis and pancreatitis).

Side effects from the cardiovascular system may be increased with increasing daily dose of ranitidine Ranitidine - help in the prevention of relapse of peptic ulcer . First, significantly reduced the number of heart rate (bradycardia), and then can join irregular heartbeat (bradyarrhythmias) and heart block (conduction disorders of heart pulses). It is also possible a significant reduction in blood pressure.

Sometimes serious violations can occur on the part of the hematopoietic system. Can reduce the number of peripheral blood white blood cell count, including granular - they can disappear completely (leukopenia, agranulocytosis - a sharp decline in immunity), platelets (thrombocytopenia - a tendency to bleed, which is especially dangerous for ulcerative lesions of the gastrointestinal tract) red blood cells (anemia), and even of all blood cells (pancytopenia). It may also suffer bone marrow, which produces these cells.

On the part of the central and peripheral nervous system while taking ranitidine may cause fatigue, irritability, weakness, drowsiness, headaches, dizziness. Rarely can develop confusion, hallucinations, and tics (involuntary muscle twitching). May be affected and the senses - sight and hearing: there are tinnitus and blurred vision associated with disorders of accommodation (the eye's ability to adapt to the vision of objects located at different distances).

Possible side effects of the endocrine system, such as an increase in the blood levels of the pituitary hormone prolactin - it helps stimulate the secretion of breast milk. The men on the background of treatment may develop changes in the body of the female type (gynecomastia), and in women - menstrual irregularities. It is also possible decreased libido and development of impotence Impotence - a female perspective on the problem .

Side effects occurring in patients receiving ranitidine, are also joint pain Joint pain - how to understand what is going on?   and muscle pain, hair loss, transient renal dysfunction. Allergic reactions - from the lungs in the form of itchy skin rashes to severe - anaphylactic shock and severe allergic skin lesions.

Contraindications for use of ranitidine

Ranitidine has little contraindications, and to avoid the side effects, this drug should be prescribed by a doctor, who at the time notice the side effects of treatment, and cancel or reduce the dosage of ranitidine.

Ranitidine is contraindicated in pregnant women and nursing mothers - the drug crosses the placenta to the fetus and is excreted in human milk. You can not assign ranitidine children under 12 years of age and in case of hypersensitivity of the patient to the components of this drug.

Zantac is prescribed with caution in the human liver and kidneys (assignment possible, but at the lower of individualized daily dose), and the combination of liver disease with metabolic and degenerative disorders of the brain (encephalopathy).

Galina Romanenko

Ranitidine is produced in the form of tablets, coated tablets and effervescent (soluble) tablets. And they both come in different doses - 150 and 300 mg. This allows the doctor and the patient to choose a convenient dosage form and dosage of the drug.

How do ranitidine tablets

When administered ranitidine tablets, coated tablets, rapidly, but not completely (only about 50%) are absorbed into the bloodstream. Maximum blood concentration of active principle is achieved in 2-3 hours acting drug for twelve hours.

Effervescent tablets quickly and completely absorbed into the bloodstream, but generally their efficiency is not very different from the action of coated tablets. This formulation of ranitidine is produced due to the fact that some patients with difficulty swallowing whole tablets and therefore prefer to soluble formulations.

Furthermore, ranitidine promotes restoration of mucosal cells of initial gastrointestinal tract, impact damage hydrochloric acid. Since the drug acts within 12 hours, it is convenient to use.

Which diseases appointed ranitidine

Ranitidine - a pill that prescribed by the physician (a pharmacy can be purchased only by prescription) in diseases of the digestive system, associated with high acidity of gastric juice.

Such diseases are primarily diseases of the stomach - a chronic gastritis with high acidity, and peptic ulcer disease. Ranitidine in the case prescribed in the complex treatment of exacerbations of the disease. It prevents the destruction of the gastric mucosa, the progression of erosive and ulcerative process, the development of internal bleeding and perforation of the stomach wall. Assign ranitidine tablets for the prevention of recurrence of the disease, which is almost always associated with high acidity of gastric contents.

One of the most severe diseases of the gastrointestinal tract is reflux esophagitis - a disease associated with a constant reflux of acidic gastric juices into the esophagus. The mucosa from the effects of such breaks, the deposition of the ulcers, often associated infection with the formation of ulcers on the walls of the esophagus, which may lead to its destruction. The appointment in this case, ranitidine Ranitidine - help in the prevention of relapse of peptic ulcer   can significantly alleviate the suffering of the patient and prevent the destruction of the walls of the esophagus.

In the duodenum and initial divisions thin as possible to develop ulcerative process, which is supported by the increased acidity of gastric juice. Sometimes this condition occurs when a benign tumor A benign tumor - is not always safe   pancreas Diabetes and pancreas - the things you need to know , Produces the hormone gastrin, which stimulates the secretion of gastric juice. The disease (it was called Zollinger-Ellison syndrome) may be accompanied by significant proliferation of ulcerative process in the upper gastrointestinal tract. In this case the Ranitidine is also widely used in the complex treatment.

How to take

Ranitidine tablets, coated tablets, taken once or twice a day, regardless of the meal (food in the stomach presence does not affect the absorption of the tablets), liquid squeezed small amount of liquid.

Soluble effervescent tablet is dissolved in a glass of water and drink after complete dissolution regardless of the meal.

But prescription dose may be either increased to 300 mg twice a day, or reduced. Individual selection of the recommended therapeutic dose below held by a physician for violations of renal and hepatic function.

Contraindications

Ranitidine Tablets - a drug, which can give a lot of side effects. Therefore, it can not be taken during pregnancy, infant feeding Breastfeeding - a personal choice   chest and for children under 12 years. In addition, ranitidine should not be taken if you are hypersensitive to its components. With care and individually selected dosage of these pills should be taken for violations of liver and kidney function.

Ranitidine Tablets - a drug, which is now widely used in the treatment of gastrointestinal disease. But taking these pills can only be prescribed by a doctor.

Galina Romanenko