Treatment of uterine fibroids without surgery is now used very widely, particularly among women of childbearing age with small and medium sized fibroids. In choosing a method of treatment the doctor is guided by a number of criteria developed specifically for the treatment of various forms of uterine fibroids.
When possible treatment of uterine fibroids without surgery
Treatment of uterine fibroids without surgery is performed only when the fibroid is small in size (dimensions correspond to the size of the uterus is not more than 12 weeks) are not growing too fast and is not accompanied by heavy bleeding and dysfunction of the adjacent organs.
Conservative treatment of uterine fibroids often used in young women who are going to have children in the future.
Today, for the treatment of uterine fibroids is issued a number of effective drugs.
Medications
The hormonal drug based therapy of uterine fibroids is suppression of female sex hormones, primarily estrogen. It estrogens cause benign tumor growths. Anything that causes stimulation secretion of estrogen leads to tumor growth and vice versa.
In order to suppress estrogen used today mainly two groups of drugs - synthetic analogues (agonists) Riesling gonadotropin hormone from the hypothalamus, which inhibits the secretion of pituitary luteinizing hormone (LH) and antigonadotropnym drugs which inhibit the action of pituitary hormones.
Conservative treatment of uterine fibroids using a gonadotropin-releasing hormone of the hypothalamus (GnRH agonists)
This group of drugs include goserelin, Zoladex, buserelin, triptorelin. As an example, consider the action of Zoladex. Zoladex suppresses LH secretion, which leads to suppression of ovarian secretion of female sex hormones and ovulation. Zoladex is a very effective drug for its effect as if ovarian function is turned off, resulting in a temporary medical castration. Without the stimulating effect of estrogen uterine fibroids are not growing, furthermore, reduced in size to an extreme level. Also stop uterine bleeding and pain.
Zoladex produced in the form of capsules for subcutaneous depot, may cause a number of side effects and has a number of contraindications.
Side effects of the drug may manifest as skin rashes, allergies, flares, sweating, headaches, irritability
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, Vaginal dryness, temporary onset of menopause, osteoporosis (brittle bones).
Do not use this Zoladex if you are hypersensitive to its components, pregnancy, breast-
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feeding, children under 14 years. With care it is necessary to take for osteoporosis and polycystic ovaries.
Conservative treatment of uterine fibroids using antigonadotropnym drugs
From this group of drugs for the treatment of uterine fibroids is most commonly used synthetic androgen (male sex hormone analogue) danazol. Its mechanism of action is associated with the suppression of gonadotropin secretion of pituitary hormones - follicle-stimulating and luteinizing hormone (FSH and LH). Available Danazol capsules for oral administration. Assign it long courses for up to six months. Under the action of danazol happening persistent suppression of ovarian function and stop the growth of uterine fibroids. However, reducing the size of myomas is not happening. It also reduces menstrual blood loss, but the mechanism of action has not been elucidated completely.
Danazol also has a number of side effects and contraindications, so it can be used only on prescription. Appointment of danazol is contraindicated in severe liver, kidney and heart with dysfunction of these organs, blood clotting and thrombosis, uterine bleeding of unknown origin, pregnancy, breast-feeding and hypersensitive to the components of the drug.
Side effects from danazol are many, including flushing, increased sweating, decrease in breast size, irritability, tearfulness, acne, increased secretion of the sebaceous glands, increased body hair, weight gain, hair loss, stomach pain
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, Transient liver function abnormalities, headache, dizziness, tremors, sleep disturbances
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, Increased heart rate, increased blood pressure.
Treatment of uterine fibroids without surgery - is a complex task that only by a specialist.
Galina Romanenko
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- treatment of uterine fibroids