Utrozhestan only available in capsules, but these capsules can be used, both internally and topically as vaginal suppositories
Vaginal suppositories - for contraception and treatment of inflammation
. It is very convenient compared to progesterone, which is produced only in the form of an oily solution for injection, and the injection is very painful.
Action utrogestan the intravaginal administration
Utrozhestan available in capsules 100 and 200 mg. Entered into the vagina utrogestan capsules dissolve slowly enough, and the maximum concentration of progesterone in the blood when it is achieved only after two or six hours. When administered twice a day the drug acts during the day. But progesterone
Progesterone - norm and pathology
rapidly (within an hour after injection) it collects in the uterus which causes rapid restoration of the correct functioning of the endometrium (the inner shell of the uterus) and its transition from the phase-expanded (proliferation) in a phase separation secretion.
After the start of pregnancy, progesterone supports the optimal development of the embryo to the endometrium.
Vaginal capsules utrogestan during pregnancy (I and II trimesters) promotes greater suppression of uterine contractility and prevent miscarriage.
Indications for intravaginal capsules utrogestan
Utrogestan Capsules can be taken orally and simultaneously administered vaginally - the dose prescribed for this doctor. Sometimes the capsule only apply vaginally, for example, if a woman has a contraindication to their ingestion (liver trouble) or the development of significant side effects as drowsiness.
Introduction capsules utrogestan vagina is indicated for replacement therapy (for example, if women are not functioning ovaries), preparation for in vitro fertilization, violations of the second phase of the menstrual cycle, premature cessation of menstruation, infertility, caused deficient in progesterone, the threat of termination of pregnancy in the I and II trimesters and for prevention of hormone disorders caused by an excess of estrogen (mastopathy, hysteromyoma, endometriosis).
How to apply
Utrozhestan in any dosage form, appoint a doctor, it also determines the dose and duration of administration, and the route of administration in the woman's body. Capsules utrogestan injected deep into the vagina, if the need arises, it is used to introduce the applicator. Utrogestan standard dose - 200 mg per day (100 mg twice daily). After the start of treatment the doctor watches the woman and, if necessary, adjust the dose.
During the menstrual cycle associated with a deficiency in the body progesterone utrozhestan inserted into the vagina by capsule twice a day for ten days, the second half of the menstrual cycle (16-17 till 25-26 day cycle).
If the ovaries of a woman is not functioning, then utrozhestan administered inserted into the vagina of 100 mg per day on the 13th and 14th days of the cycle, then increase the dose to 100 mg twice daily and is administered from the 15th to 25th day cycle. On the 26th day of the menstrual cycle
The days of the menstrual cycle: Four phases
and after the beginning of pregnancy utrogestan dosage is increased by 100 mg per day, every week, gradually reaching the maximum (600-800 mg per day, divided into three portions). Such a dosage may be used within two months.
In threatened miscarriage and for preventing habitual miscarriage amid lack of progesterone administered utrozhestan I and II trimester of pregnancy (prior to 20 weeks) 200-400 mg per day - the capsule 100 or 200 mg twice a day.
Contraindications for introducing capsules into the vagina
Introduction utrogestan vagina is contraindicated in hypersensitive to the components of the drug, bleeding and spotting (if the reason they are not installed), incomplete abortion (where to save the child is no longer possible), porphyria (severe congenital metabolic disorders), hormone-dependent tumors of the breast and genital organs of a woman.
The caution administered utrozhestan
Utrozhestan - corrects the deficiency of progesterone
in chronic hepatic and renal failure, thrombosis, varicose veins, diseases of the heart and blood vessels, diabetes, asthma, epilepsy, migraine, depression, disorders of lipid metabolism, in the III trimester of pregnancy (threat of increased load on the liver).
Side effects
Common side effects usually develop when taking utrogestan inside the intravaginal use of them almost never happens.
However, there may be side effects such as a reduction in the length of the menstrual cycle, intermenstrual bleeding and spotting. Most often, these side effects occur with an overdose of the drug and are in dose reduction. Allergic reactions are also possible.
Utrozhestan - a hormonal drug, and it can only appoint a doctor.
Galina Romanenko