Augmentin - suspension for the treatment of infections in young children and adults
September 28, 2012
Augmentin in the suspension - a convenient dosage form of the antibiotic
Antibiotics - whether they will help you in the foreseeable future?
broad spectrum for the treatment of children. The drug is well tolerated even by very young children, the only obstacle to its use are allergic reactions that often develop on antibiotics penicillin.
How does augmentin suspension
Augmentin suspension refers to "protected" semisynthetic penicillins. It is a broad spectrum antibiotic amoxicillin, the effect of which is protected and reinforced clavulanic acid. Such protection is needed drugs penicillin because some infectious agents produce specific enzymes (beta-lactamase), destroy them, which significantly narrows the range of action of these drugs.
Clavulanic acid chemical structure is similar to beta-lactamases and, therefore, can be firmly block their action. Furthermore, this substance also possesses some antibacterial activity. However, amoxicillin clavulanic acid forms an antibiotic resistant against the penicillins destructive enzymes, and therefore the spectrum of its activities is much wider than that of other drugs penicillin.
The slurry produced in the form of powder, from which at home can prepare a drug added in accordance with the instruction a certain amount of boiled water. Furthermore augmentin (5 mL finished suspension contains 125 mg of amoxicillin and 31, 25 mg clavulanic acid) in the slurry have additional ingredients: Xanthan gum, aspartame, succinic acid, colloidal silica, hydroxypropyl methylcellulose, silica, flavors.
Sensitivity to show Augmentin most pathogens causing infectious-inflammatory diseases in children. After ingestion (food intake does not affect the rate of absorption) absorbed slurry in the gastrointestinal tract into the bloodstream and distributed to the tissues. Augmentin output substantially unchanged excretion in six hours after administration of the suspension.
To be appointed
Augmentin suspension may be imposed, for both children and adults, but most of it is still used to treat infectious and inflammatory diseases in children caused by susceptible to infectious agents Augmentin.
Very often in Augmentin suspension is used for the treatment of acute and chronic bacterial infections of upper respiratory tract and respiratory tract - sore throats, tonsillitis, pharyngitis, otitis, sinusitis, sinusitis, otitis, bronchitis.
Augmentin suspension also often prescribed for the treatment of diseases of the kidneys and urinary tract. The suspension can be assigned in acute and chronic cystitis
Chronic cystitis: a correct diagnosis - the main
, As well as a moderate course of pyelonephritis. Will it also in bacterial vulvovaginal
Vulvovaginitis - a disease of children and the elderly
girls. Adults suspension can also be used in infectious and inflammatory diseases of the genital organs and genital infections (for example, gonorrhea).
Apply suspension as in purulent infections of the skin and soft tissue - boils, carbuncles, and so on, and in diseases of the joints and bones - arthritis and osteomyelitis with a moderate course (with severe diseases of Augmentin administered by injection).
In some cases, augmentin suspension is contraindicated
Augmentin suspension is contraindicated in case of hypersensitivity to its components of the patient, with severe liver disease with dysfunction of this body.
With caution and only on prescription augmentin suspension should be taken by pregnant women, and patients with impaired renal function (dose in this case is often reduced and selected individually).
Do suspension augmentin side effects?
Side effects are, but they are not many. The main side effect augmentin suspension, as well as its other dosage forms are allergic reaction. They can be mild or severe leak, but in any case require the discontinuation of the drug.
Furthermore, when receiving the slurry may cause discomfort by the gastrointestinal (nausea, vomiting and diarrhea), and therefore it is recommended to take the suspension immediately before meal. There is also the risk of dysbacteriosis and inflammation in the intestine. Augmentin may have adverse effects on the liver, which is manifested as a change in laboratory parameters as well as jaundice.
Perhaps the emergence of headaches, dizziness
Dizziness - if the ground is slipping from under his feet
, Seizures, agitation, violations of the kidneys, reducing the number of leukocytes in the blood, red blood cells and platelets.
Galina Romanenko
Doxycycline - description of the antibiotic and its spectrum
February 11, 2014
Doxycycline - description of modern semisynthetic antibiotic tetracycline indicates that it has a broad spectrum of activity, but unlike other drugs in this group (including tetracycline itself) differ much less toxicity.
Features of action of doxycycline
Doxycycline - today it is a popular semi-synthetic antibiotic tetracycline. The peculiarity of its action is that having the same action mechanism as that of other antibiotics of this group (the suppression of the protein metabolism in the cell membrane of pathogens of bacterial origin, including those located intracellularly) has a higher efficiency and lower toxicity.
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High antimicrobial activity allows the use of this drug in doses several times smaller than a number of other antibiotics (such as natural antibiotics tetracycline and oxytetracycline), which significantly reduces its toxic effect on the body, especially the liver.
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A feature of doxycycline is also better intestinal absorption and longer duration of action.
The popularity of this drug today is due to the fact that it is effective against such intracellular pathogens located infections like chlamydia
Chlamydia: insidious and widespread disease
, Mycoplasma and Ureaplasma, which are often the cause of long-term infection and inflammatory processes.
Doxycycline is active against many Gram-positive and Gram-negative microorganisms are the cause of upper respiratory tract infections, respiratory system, biliary tract and the digestive system, kidney and urinary tract, eyes, skin, soft tissues, bones and joints.
Doxycycline is also effective against the causative agents of especially dangerous infections, such as cholera, plague, anthrax, tularemia. It is successfully used in dysentery and other intestinal infections of bacterial origin, whooping cough
This pest, pest whooping ...
, Syphilis, gonorrhea, brucellosis, yersiniosis, malaria and other infections.
Doxycycline under different names (vibramitsin, doksibene, tetradoks, JUnidoks soljutab and others) produce different pharmaceutical companies in a variety of dosage forms - tablets, capsules, syrup, and the freeze-dried for solution for infusion.
Which diseases doxycycline
Doxycycline prescribed for infectious and inflammatory processes caused by microorganisms sensitive to it:
- infections of the upper and lower respiratory tract infections - pharyngitis, laryngitis, bronchitis, pneumonia;
- infections, eye and ear;
- infections of the gallbladder and biliary tract;
- infections of the gastrointestinal tract and rectum;
- purulent infections of the skin and soft tissues, including the acne
Acne: facial trouble
;
- Some sexually transmitted diseases - syphilis, gonorrhea, and so on;
- infections, sexually transmitted infections, including those caused by intracellular pathogens located - mycoplasmosis, ureaplasmosis, chlamydia;
- infections of the urinary tract;
- osteomyelitis (bone inflammation) and others.
This doxycycline is contraindicated
Doxycycline is contraindicated in:
- increased sensitivity to tetracyclines;
- Pregnancy and lactation
Breast-feeding: feed - and no nails!
Child;
- children up to 8 years;
- severe hepatic impairment;
- increased sensitivity to light, including the porphyria - a hereditary disease, which manifests itself as a violation of pigment metabolism, photodermatosis and other symptoms.
How Toxic doxycycline
Doxycycline is the most toxic antibiotic tetracycline, however, like other antibiotics of this series, it can produce a number of side effects, especially with prolonged use at high doses
When applying the ego may cause disturbances of appetite, nausea, vomiting, diarrhea, inflammation of the mucous membrane of the tongue, small intestine and colon, transient liver dysfunction, candidiasis. Perhaps the emergence of side effects in the central nervous system in the form of increased intracranial pressure, dizziness, gait and coordination of movements, so during treatment should refrain from driving a car.
Side effects can manifest themselves in the form of increased bleeding, decreased immunity, hemolytic anemia, impaired growth in children, irreversible changes in the color of teeth, the structure of tooth enamel, allergic reactions (including sensitivity to light).
Doxycycline is the same as the rest of the antibiotics tetracycline, can be taken only on prescription.
Galina Romanenko
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