Those who live in rural areas, usually knows what brucellosis, as they often become infected by sheep and cattle and pigs. Infected with brucellosis is not difficult, but the cure - it is a problem, especially in lesions of the musculoskeletal system. Therefore, in this case it is best to take preventive measures to prevent possible contamination.

Brucellosis - an infectious disease caused by bacteria of the genus Brucella. This infection affects mainly animals, including goats, sheep, camels, pigs, elk, deer, cattle and dogs. In humans brucellosis develops in contact with infected animals or products from the milk or meat of infected animals. The symptoms of brucellosis are often similar to symptoms of the flu.

Human Brucellosis is found worldwide; year recorded more than 500,000 cases of infection by the disease. It is most common in areas where the veterinary control system does not work very effectively. In the high risk area is the Mediterranean basin (Portugal, Spain, Southern France, Italy, Greece, Turkey and North Africa), South and Central America, Eastern Europe, Africa, Asia and the Caribbean.

History of brucellosis

The first description of brucellosis was made by Hippocrates more than 2,000 years ago. In 1887, British physician David Bruce identified the microorganism that causes brucellosis, several infected patients on the island of Malta. Throughout its history of this disease have been a lot of different names, including Maltese and Mediterranean fever, as well as undulating fever (due to the recurrent nature of the fever that occurs during illness).

In the middle of the twentieth century in the United States Brucella bacteria learned to use as a biological weapon. In 1969 President Nixon banned such use brucellosis.

What is brucellosis?

Brucellosis - is a systemic infectious disease that is transmitted from animals to humans of certain (or zoonotic diseases). Brucellosis is caused by human preferably by four species of bacteria Brucella: Brucella melitensis (it is transferred goats, sheep and camels), Brucella suis (pigs), Brucella abortus (cows, buffaloes, elks, yaks), Brucella canis (dogs). These bacteria can cause human brucellosis, but is most common in the world of Brucella melitensis, and it also causes the most severe forms of brucellosis.

How is brucellosis?

Brucellosis is transmitted from animals to humans in several ways. This occurs most often when using raw milk or cheese made from unpasteurized milk of infected sheep or goat.

If inhaled microorganisms or by direct contact with a person infected animals secret people can also become ill with brucellosis. Thus brucellosis can be an occupational disease of veterinarians, abattoir workers, hunters, laboratory staff, where he studied the animals, farmers and shepherds.

Finally, accidental injection of vaccine Brucella abortus, intended for cattle, too, can cause brucellosis in humans. Transmission of brucellosis from human to human is very rare and can happen through sexual contact or through breastfeeding Breast-feeding: feed - and no nails! .

Symptoms of brucellosis

The incubation period of brucellosis lasts a couple of days to several months. Some people have very mild symptoms of the disease, while in others the symptoms are severe and persist for a long time. Symptoms of brucellosis diverse and resemble symptoms of many other febrile illnesses. Among them:

• Fever (often meets, may be intermittent or recurrent)
• Increased perspiration
• Muscle aches
• Pain in the joints
• Weakness
• Dizziness
• Headache
• Depression
• Irritability
• Loss of appetite
• Weight loss
• Cough
• Heavy breathing
• Chest pain
• Stomach ache
• Enlarged liver and / or spleen

Brucellosis can occur and many other symptoms.

Complications of brucellosis

In general, with timely treatment and proper use of antibiotics Antibiotics - whether they will help you in the foreseeable future? , The prognosis for patients with brucellosis is very optimistic. Mortality from this disease is low - less than 2%. However, some may develop complications affecting some organ systems:

• The bones and ligaments - sacroiliitis, spondylitis, and osteomyelitis
• Cardiovascular system - endocarditis (most often cause of death from brucellosis), myocarditis, pericarditis
• Central nervous system - meningoentsifalit
• Gastrointestinal system - Hepatitis Hepatitis - the scourge of our time , Liver abscesses, colitis, and spontaneous peritonitis
• Genito-urinary system - orchitis
• Bronchopulmonary system - pneumonia
• The visual system - optic neuritis Neuritis - nerve damage   and uveitis

Today, some modern and effective antibiotics are available in the form of a dosage form soljutab. This allows the active substances quickly absorbed in the gastrointestinal tract and immediately rush to the site of inflammation.

What are the characteristics of the dosage form soljutab

The word "soljutab" is translated as a tablet, a water-soluble (dispersible). A feature of this formulation Wilprafen is that the active substance Tablets (josamycin) is placed in a special microspheres which do not allow it to collapse in the acidic environment of the stomach.

This soluble tablet is absorbed in the intestine much faster and fuller than usual, so almost no negative impact on the natural intestinal flora. Tablets soljutab quickly enter the bloodstream and out to the lesion, quickly creating a therapeutic concentration and the output is then excreted in the bile and feces.

What matters is the fact that tablets soljutab there is a minimal amount of flavored - no sugar, gluten and common allergens, etc. Masking of taste is mainly due to the predictable failure of the microspheres in the duodenum. This significantly reduces the allergenicity Wilprafen soljutab and distinguishes it from other liquid dosage forms, such as suspensions. Vilprafen soljutab produces a Dutch pharmaceutical company Astsllas Pharma Europe BV

How does vilprafen soljutab

Active ingredient is Wilprafen soljutab josamycin (macrolide antibiotic), each tablet contains 1000 mg of it, that is two times higher than in a conventional tablet Wilprafen. Adjuvants vilprafene soljutab are microcrystalline cellulose, giproloza, docusate sodium, aspartame, colloidal silicon dioxide, strawberry flavor, and magnesium stearate.

Vilprafen soljutab used to treat bacterial infection and inflammatory processes caused by susceptible to the antibiotics. It inhibits the formation of protein in bacterial cells necessary for their livelihoods.

At recommended doses, the drug has a bacteriostatic effect (inhibits the proliferation of the infectious agent), but at higher doses can also have a bactericidal effect (kills bacteria). That formulation soljutab allows you to create the source of infection high concentrations of active principle.

Sensitivity to Josamycin show intracellular pathogens infection - chlamydia Chlamydia: insidious and widespread disease , Mycoplasma, ureaplasma This insidious ureaplasma - often too late   and Legionella, which are often hidden and cause long-occurring infectious and inflammatory processes. In addition, josamycin sensitive Staphylococcus aureus (the most pathogenic form of staph), pyogenic streptococci, pneumococci, diphtheria bacillus, meningococcus, gonorrhea, Haemophilus influenzae, Clostridium perfringens some species (cause foodborne and gas gangrene), and so on.

Vilprafen soljutab in most cases exhibits activity against infectious agents sensitive to erythromycin (it is the first macrolide). Resistance (decrease in sensitivity) of infectious agents to vilprafenu soljutab develops very slowly.

The drug is nontoxic and does not in most cases dysbacteriosis (number of cases is smaller than with conventional tablets vilprafen) have been completely absorbed in the duodenum and the intestine misses.

With which diseases and how to apply

Vilprafen soljutab prescribed for infectious and inflammatory processes in the various tissues and organs caused by bacteria susceptible to josamycin. It respiratory diseases, upper respiratory tract, eye, urogenital system, skin and subcutaneous tissue, and so on. Furthermore, vilprafen Vilprafen - modern highly effective and non-toxic antibiotic   soljutab prescribed for infectious diseases such as whooping cough This pest, pest whooping ... , Diphtheria, scarlet fever, anthrax, erysipelas.

Vilprafen soljutab pre should be dissolved in a spoonful of water (at least 20 ml). You can take a pill and a whole with water, but it is slowly absorbed.

Contraindications and side effects

Vilprafen soljutab almost no contraindications and side effects. It can not be taken only if hypersensitivity to the drug and in severe liver failure. In renal insufficiency, the drug is used with caution.

Side effects are the most common disorders of the gastrointestinal tract - nausea, vomiting and diarrhea. Sometimes there are short-term disturbances of liver function and hearing loss, as well as allergic reactions.

Vilprafen soljutab most convenient for the patient the dosage form of the drug, moreover, it enhances the effectiveness of treatment.

Galina Romanenko