Protargol as an effective drug for local application of antibacterial and anti-inflammatory known for a long time. Very often it was administered to children. But recently, the drug was banned in several countries for use for children under six years.
The mechanism of action protargola
Protargol (international non-proprietary name - silver proteinate) - a powder containing 7, 8-8, 3% of silver, from which industrial pharmacy prepared single five-percent aqueous solution that is used in the form of eye drops, nose drops and solutions for lavages Bladder
Urinary bladder - structure and function
When ingested proteinate silver dissociates to form ions of silver, which have astringent, antiseptic and anti-inflammatory effect. The silver ions actively suppress the proliferation of pathogens, linking their DNA. Protargola mechanism of action is based on the fact that the silver ions on the damaged mucosa precipitated proteins and form a protective film. This reduces the sensitivity narrowed blood vessels (this leads to the reduction of edema) and suppress the inflammatory process. The silver ions also inhibit the proliferation of various bacteria.
Anti-inflammatory properties of silver have been known to Avicenna, who applied for the treatment of patients with silver dust. He first described the bluish coloring of the eyes associated with the ingestion of silver (argyria). In those days, when there were no antibiotics were invented, drugs commonly used for the treatment of purulent diseases, especially of purulent wounds.
Repeated drug craze silver began several decades ago in the United States. Patients self-produced "silver water" and drank it, and the company produced biologically active food supplements, which contain silver in doses far exceeding permissible. There were multiple cases of argyria - life staining of the skin in a dark color. In this regard, in the late nineties vulgar century silver US drugs were banned. In many other countries Protargolum not licensed for use for children under six years. In Russia there are contraindications for taking this drug is not.
Today Protargolum not as widely used, despite its effectiveness, as is increasingly the question is raised about its side effects in the form argyrosis. Nevertheless, it continues to be successfully used in otolaryngology, ophthalmology and urology.
How to apply Protargolum
Protargola aqueous solution of various concentrations (one-five per cent) is used to treat infectious and inflammatory processes of the eye. Protargola solution instilled into the eyes of two or three drops from two to four times a day. For the treatment of infectious and inflammatory diseases of the bladder and urinary tract infections used a two-percent solution protargola who spend washing of the urinary tract. For the treatment of upper respiratory tract - rhinitis, inflammation of the pharynx, middle ear nose buried three to five drops twice a day, two-percent solution protargola.
Before burying protargola of nasal mucus must be removed, this is best done with the help of drops on the basis of sea water (for example, drops Aqua Maris) or a two percent solution of soda (a teaspoon of baking soda in a glass of boiled water). The duration of treatment protargola
Protargol - Pharmacy survivor
It is two weeks, if necessary, extend the course. We must remember that Protargolum protein preparation and therefore has a short shelf life. He kept only in a dark container.
Do not use this protargola case of hypersensitivity to the drug a patient's body during pregnancy and nursing
Breastfeeding - a personal choice
Side effects when using protargola rare. The main side effect - it is dry mucous membranes, burning and itching in the area of topical application of the drug. There may be also a feeling of numbness at the site of impact, headache, dizziness, lethargy, drowsiness. There are also allergic reactions.
Indications for use protargola
Indications for use protargola are:
- purulent conjunctivitis, especially gonorrheal origin; the newborn immediately after birth have been prevented gonoreynogo ocular drugs silver;
- acute and chronic rhinitis;
- inflammation of the pharynx (acute and chronic faringoit);
Inflammation of the bladder - inconvenient and unpleasant
In theory, long-term use at high doses protargola may appear argyrosis - resistant dyeing gray or bluish color of the skin and mucous membranes. Danger argyrosis that lifelong changes in skin color. But in practice, the application of conventional doses and prescribed course of treatment by the application of protargola argyrosis not found.