- Interferon - protects against diseases of the new century?
- The main antiviral agent
The main antiviral agent
Interferons have been opened at the beginning of the second half of the last century. Experimentally it has been found that cells infected with influenza virus, produce and secrete into the surrounding medium proteins retard intracellular viral multiplication. These proteins called interferons. Protecting the body from viral infection depends on the amount of interferon produced by the cells.
Interferons are of different types: alpha, beta and gamma interferons. The first found the use of alpha-interferon produced by blood lymphocytes. His was prepared from donated human blood after exposure to the virus, so it became known as the human leukocyte interferon. Next, interferon alpha steel obtain genetically engineered bacteria of the amino acids. Such interferon called recombinant human. With alpha-interferon, and gamma-interferons learned to treat acute viral infection (such as influenza) chronic viral diseases (hepatitis, herpes, etc.). The beta interferons useful in the treatment of multiple sclerosis.
Human leukocyte interferon
Human leukocyte interferon, obtained from donated human blood after exposure to the virus has the ability to stimulate phagocytic activity of blood cells (phagocytes are large cells that capture and absorb viruses). This preparation produced a dry matter in vials to prepare a solution and used for preventing and treating influenza and other acute respiratory viral infections by instillation into the nose. Efficacy is higher the earlier date of application. Human leukocyte interferon necessarily checked for the presence of antibodies to the HIV virus and hepatitis C and B.
Human recombinant interferon
Human recombinant interferon completely eliminates the possibility of contracting a viral infection of its use, since its preparation not using human blood. It is produced in the form of various preparations, the most common of which is viferon. Viferon has a strong antiviral and immunomodulatory (reducing immunity) effects. Immunomodulatory effect contributes to antimicrobial activity expressed viferona.
In addition to alpha-interferon viferon contains tocopherol
Vitamin E (tocopherol) - not to be carried away
and ascorbic acid, which enhance the antiviral activity of interferon-alpha and contribute to enhanced development of the body's own interferon. Viferon used in a variety of infectious and inflammatory diseases caused by bacteria or viruses, with intrauterine infection (diseases of the fetus occurred before he was born), such as chlamydia, herpes, mycoplasmosis
Mycoplasmosis - infection does not always equal disease
, Chronic viral hepatitis, for the treatment of urogenital infections in pregnant women (chlamydia, mycoplasmosis, herpes, etc.) - as an immunomodulator, and herpes also as antiviral agent for the treatment of influenza and other acute respiratory diseases, including complicated bacterial infection.
Viferon increases resistance in relation to any infection, but it is especially effective in viral diseases.
The beta interferons
Beta interferons have been used in the treatment of multiple sclerosis
Treatment of multiple sclerosis - the choice is always
- Severe progressive disease, which resulted in damages the nervous system and the person gradually becomes completely immobile. Causes of this disease are not fully established, but it is believed that it has an infectious-allergic nature. Until now, the disease is considered incurable, but with the advent of beta-interferons have the opportunity to suspend its progression. Beta interferons (such as Betaferon) has antiviral and immunoregulatory activity. Mechanisms of action of Betaseron for multiple sclerosis
Multiple sclerosis - whether in remission?
not finalized, but work in this direction are carried out.
Features of gamma-interferon can demonstrate drug Ingaron - human recombinant interferon-gamma. Ingaron has antiviral and immunomodulatory properties, activates certain types of white blood cells to protect against infections, blocks the formation of viral proteins and assembly of the mature virus particle, causes the death of intracellular bacteria, destroys virus-infected cells. It is used to treat chronic hepatitis C and HIV - infection, pulmonary tuberculosis, chlamydia, herpes, cancer. In acute respiratory viral infections and flu bury him in the nose.
Ingaron used to restore cellular immunity disorders and for treatment of certain infectious diseases, allergies, autoimmune diseases and cancer.
Interferons - high, but still not completely fully investigated biologically active substances which, however, have found widespread use in the treatment of various diseases.