Cytomegalovirus and immunity - the concept is closely related

July 31, 2012

 CMV immunity
 Cytomegalovirus (CMV) - is one of the most common virus in nature; it is present in the blood of the majority of mankind, without causing the disease, as the normal state of the immune system The immune system - how it works?  The immune system - how it works?
   for it is an insurmountable obstacle. Mankind has not yet learned to deal with this virus, as well as most viral infections.


What is different from other viruses cytomegalovirus

A distinctive feature of the cytomegalovirus is that, once in the human body, which has a normal immune system, it is embedded in the sensitive cells, and it is preserved for a long time there, staying in an inactive state. Sensitivity to cytomegalovirus show, first of all, the cells of the salivary glands. Furthermore, cytomegalovirus may "hide" in the cells of other endocrine glands, the epithelium of the cervix, kidney and elsewhere.

Thus, cytomegalovirus can "sit" in the human body for the rest of life, and never cause illness. But once significantly reduced immunity, cytomegalovirus is activated, destroying the cell nuclei, in which the "hiding", and other intracellular structures. As a result, the cell attracts fluid swells and takes on a characteristic appearance, which is why, and was called "owl eyes". Breeding cytomegalovirus is first inflammation in the salivary glands, and then spreads to the entire body.


Harmful if cytomegalovirus

For the majority of the population is not dangerous cytomegalovirus. If an adult is slightly reduced immunity, the cytomegalovirus infection may start, but it occurs in the form of its local form - inflammation in the salivary glands or other organs. But such a patient poses a risk as a source of infection as CMV can be transmitted by airborne droplets, contact and sexually.

Cytomegalovirus is a special danger to pregnant women because it can pass through the placenta and cause fetal infection in the fetus. This intrauterine infection rarely ends well: the child dies or in the womb or at birth, and if survives, the severe consequences of violations of mental development of hydrocephalus (hydrocephalus brain), microcephaly (underdevelopment of the brain), blindness, deafness and other diseases.

Infection and child during childbirth, if cytomegalovirus present in mucosal cells of the cervix. Newborn babies and seriously ill cytomegalovirus infection due to immaturity of the immune system Immunity - types and characteristics in children in adults  Immunity - types and characteristics in children in adults
   - They develop a generalized form of the disease with lesions of the internal organs.

Adults also can develop a form of generalized cytomegalovirus infection if they have sharply reduced immunity. Immunodeficiency observed in AIDS, cancer patients receiving treatment, overwhelming the immune system, and in patients undergoing organ transplantation with advanced artificial suppression of the immune system. This group of patients and pregnant women is a compulsory study of cytomegalovirus Cytomegalovirus - what is its danger?  Cytomegalovirus - what is its danger?


How to implement the body's immune system reacts to cytomegalovirus

The immune system in most cases passes CMV to the body, allowing him to "hide" in sensitive cells and preserved, but multiply it does not allow it.

In response to the introduction into the body of CMV produces special proteins - immunoglobulin (Ig) of different classes, which are commonly called antibodies Antibodies - "soldiers' immunity  Antibodies - "soldiers' immunity
 . Thus, immediately after the introduction of cytomegalovirus immune system produces IgM. The presence in the blood of pregnant women IgM speaks of the danger threatening the fetus, since the introduction of the primary cytomegalovirus can always end up developing an infection that can get through the placenta to the fetus and cause fetal infection. IgM antibodies can not stop this infection. But if a woman's body increases the titer of IgG, this is a good sign - such antibodies will protect the woman and the fetus from infection.

So today, when various kinds of latent infection can complicate pregnancy, obstetricians recommend that women conduct a survey in the process of planning. If the blood of a woman who plans to become a mother, will show up antibodies IgG, then it has nothing to fear - protection against CMV is present.

If no such antibodies means that the body is open to infection, which can infiltrate into it at any time. A primary infection during pregnancy, as already mentioned, is dangerous. Therefore, such women are recommended during pregnancy to avoid visiting public places, and especially less contact with children who are the most likely sources of cytomegalovirus infection.

Immunity - is our main protection against viruses, since virus infection mankind has not learned to fight.

Galina Romanenko

Article Tags:
  • immunity
  • Cytomegalovirus

TSikloferon ampoules for treating chronic viral and bacterial infections

March 4, 2012

 tsikloferon ampoule
 TSikloferon has antiviral, anti-inflammatory and immunomodulatory effects, it is very well suited for the treatment of chronic viral infection, which is prolonged, often quietly and almost always accompanied by a decrease in immunity.

 TSikloferon ampoules for treating chronic viral and bacterial infections

How does tsikloferon ampoules

TSikloferon - is an interferon inducer, ie it stimulates the formation of the antiviral protein interferon, which destroys pathogens of viral origin. Safety tsikloferona even administered in the form of injections because the protein is not a foreign interferon (produced outside the body), it produces its own body and thus tsikloferon almost no side effects.

Sensitivity to show tsikloferon virus pathogens flu, SARS, tick-borne encephalitis, influenza, hepatitis, herpes, cytomegalovirus, HIV, HPV (human papilloma virus), various enterovirus and many others.

In ampoules tsikloferon help not only in viral and bacterial infection, as it is an immunomodulator and stimulate the immune response of the organism to the introduction of any infection. Therefore, it is prescribed in severe bacterial infections occurring acute and chronic smoldering infections that are accompanied by a decrease in immunity. In addition, it is able to enhance the effect of antibacterial drugs.

When systemic connective tissue diseases it suppresses autoimmune processes (allergic to the body's own tissues), analgesic and anti-inflammatory action.

When cancer it inhibits the ability of tumor cells to reproduce, which prevents as the growth of the tumor and metastasis Metastasis - danger everywhere  Metastasis - danger everywhere

Despite the diversity of their actions tsikloferon is absolutely non-toxic drug. Even with long-term use it does not cause the body mutations (genetic changes), abnormalities of organs and systems of the fetus, toxic effects on the fetus (confirmed only by laboratory tests on animals, no clinical trials on pregnant women) and carcinogenic effects (ie, cancers).

TSikloferon ampoules available as 12, 5% aqueous solution for injection to 2 ml (1 ml contains 125 mg of active substance).

 TSikloferon ampoules for treating chronic viral and bacterial infections

Which diseases prescribed

TSikloferon ampoules usually part of a comprehensive treatment of adult patients with:

  • HIV infection;
  • neuroinfection caused by various viral pathogens (tick-borne encephalitis, Lyme disease, serous meningitis and encephalitis caused by any virus infection);
  • acute and chronic viral hepatitis;
  • herpes infection;
  • CMV;
  • immunocompromised, develop on the background of acute and chronic bacterial and fungal infections;
  • Chlamydia infection;
  • rheumatic and connective tissue diseases (scleroderma, systemic lupus erythematosus and other);
  • exchange (degenerative-dystrophic diseases) joints.

Babies tsikloferon ampoules used (as in the complex treatment) for acute and chronic viral hepatitis, herpes infection and HIV infection.

 TSikloferon ampoules for treating chronic viral and bacterial infections

Contraindications and side effects

TSikloferon contraindicated in severe liver disease with severe violation of its functions and hypersensitive to the components of the drug.

During pregnancy, breast- Breastfeeding - a personal choice  Breastfeeding - a personal choice
   chest and under the age of four years tsikloferon contraindicated, since the data of patients in clinical trials have not been conducted.

TSikloferon gives no side effects other than allergic reactions. In some cases, it can give complications in diseases of the thyroid gland The thyroid gland - is responsible for your hormones  The thyroid gland - is responsible for your hormones
 So tsikloferon TSikloferon - restores the body's defenses  TSikloferon - restores the body's defenses
   ampoules at such a disease is administered only if prescribed by and under the supervision of an endocrinologist.

Overdose tsikloferona even when parenterally (bypassing the gastrointestinal tract) administration was observed. This drug can be administered simultaneously with any antiviral and antibacterial agents, the effect of which thus increases. Cycloferon is also able to reduce the side effects that occur with the introduction of exogenous interferon and after a course of chemotherapy in cancer patients.

TSikloferon ampoules - is an effective antiviral and immunomodulatory agent which has been used in the treatment of many people, both viral and bacterial infections. It is used and in many other diseases, which are accompanied by a decrease in the body's defenses.

Galina Romanenko

Article Tags:
  • tsikloferon