Rimantadine (active ingredient - rimantadine) - this is an antiviral drug that has a pronounced activity, especially for influenza A virus In addition, it reduces symptoms of toxicity of the flu, including the flu caused by virus type B is used as it is in the tick-borne encephalitis.
How does rimantadine?
Rimantadine inhibits virus replication after entry into cells, i.e. at the early stages of the disease. In later stages it is not so effective. High sensitivity to rimantadine exhibit influenza viruses A2, but other strains of influenza A virus is also susceptible to it. The flu caused by any virus, rimantadine reduces the manifestations of toxicity, the general condition of patients at his reception improves. In addition, sensitivity to rimantadine exhibit encephalitis virus. Other acute and chronic viral infections of the drug is not effective.
After ingestion rimantadine slowly absorbed in the intestine into the blood, which is stored for at least 6-8 hours. The preparation is then decomposed into metabolites and excreted through the kidneys. If impaired renal function, rimantadine that may accumulate in the blood in high concentrations that may be toxic to the organism.
The use of rimantadine
Apply rimantadine in influenza caused by virus type A (especially A2). It is effective at the beginning of the disease, as it can significantly reduce its severity. In later stages, when the virus has multiplied significantly in the cells of the patient, rimantadine becomes ineffective. The flu caused by virus type B, it can also improve the condition of the patient at the expense of intoxication.
Apply remantodin and for the prevention of influenza caused by viruses types A drug is especially effective when used in a flu epidemic among the members of a team, a family.
Rimantadine is also used in the spread of tick-borne encephalitis virus with the purpose of prevention and treatment.
Treatment Plan
Rimantadine produced in the form of tablets of 50 mg (they are used for the treatment and prevention of diseases in adults and children over seven years), as well as syrup for children after year. It is used in, after a meal with water. The circuit for receiving rimantadine in influenza in adults: the first to put - in the 2 tablets 3 times a day; second day - 2 tablets 2 times a day, the third day - 2 tablets one time per day.
The dosage regimen of tablets rimantadine in children (designed for 5 days), aged 7 to 10 years - 1 tablet 2 a day; aged 11 to 14 years - 1 tablet 3 times a day.
The dosage regimen syrup rimantadine for children from 1 year to 3 years: on the first day of 2 teaspoons (10 ml or 20 mg) three times a day, the second and third day - 2 teaspoons 2 times a day, the fourth day - 2 teaspoons 1 per day.
The dosage regimen syrup rimantadine for children from 3 to 7 years: the first day 3 teaspoons (15 ml or 30 mg) three times a day, the second and third day - 3 teaspoons 2 times a day, the fourth day - 3 teaspoons Spoon 1 per day.
For the prevention of influenza rimantadine prescribed one tablet 1 time a day for two weeks. To prevent tick-borne encephalitis virus nature (it must begin to conduct no later than two days after a tick bite) adult rimantadine prescribed 2 tablets, 2 times a day for three - five days. People who reside in the area, Tick-borne Encephalitis infected, prevention can be carried out within two weeks.
Contraindications
Admission rimantadine is contraindicated in case of hypersensitivity to the drug, severe liver disease in violation of their functions under any kidney disease, elevated thyroid function
The thyroid gland - is responsible for your hormones
During pregnancy and breastfeeding
Breast-feeding: feed - and no nails!
baby and children up to one year. Rimantadine tablets are contraindicated for children under 7 years.
With caution and only on prescription rimantadine can be taken in the seizure (including epilepsy), stroke and diabetes
Diabetes - threatening and incurable disease
.
Side effects
Rimantadine has a number of side effects. It is a violation on the part of the digestive system (change in appetite, nausea, vomiting, pain in the upper abdomen, bloating, transient liver dysfunction) and central nervous system (headache, dizziness
Dizziness - if the ground is slipping from under his feet
, Depressed mood, lethargy, irritability, weakness, nervousness, drowsiness or insomnia, trembling of the hands, the feet, the whole body, impaired concentration), allergic rash (including rash), itching).
When receiving rimantadine can begin aggravation of comorbidities in elderly patients with high blood pressure increases the risk of bleeding in the brain in patients with epilepsy - the risk of seizures. Rimantadine also reduces the effect of antiepileptic drugs and intensifies the effects of caffeine exciting.
Galina Romanenko