Ointment prednisolone's anti-inflammatory and has a strong anti-allergic effect. But this greatly disturbed immune system of the skin, which promotes bacterial, fungal and viral infections. Therefore, prednisolone ointment is not shown at all skin diseases.

How does prednisolone ointment

Prednisolone is for external use is available in the form of 0, 5% ointment prednisolone (1 g of ointment contains 5 mg of prednisone).

Prednisolone ointment is fast and effective local anti-inflammatory, anti-allergic effect, relieves swelling of the skin and subcutaneous tissue, itchy skin. Prednisolone penetrates the skin cells and inhibits the synthesis of biologically aktivynyh them substances that promote the formation of inflammation and allergies.

Prednisolone ointment also suppresses the formation of skin cells of nucleic acids (including DNA) that suppresses the proliferation of skin cells, including cells of the connective tissue - it prevents the formation of rough scars on the skin, which may be a consequence of inflammation and wounds.

Prednisolone ointment antiallergic action associated with a reduced number of basophils in the peripheral blood and suppressing the formation and secretion of biologically active substances involved in the allergic process such as histamine.

Decomposed prednisolone Prednisolone - against inflammation, allergy and pain, but with complications   in the liver and then excreted through the gastrointestinal tract and kidneys. Prednisolone well penetrates through the placenta to the fetus and is excreted in human milk.

With which diseases and how changes in the prednisolone ointment

Prednisolone ointment, as well as other dosage forms of prednisolone, can only be used by a physician. Assign her skin diseases infectious origin, such as atopic dermatitis, atopic dermatitis, eczema is true, seborrheic dermatitis, psoriasis, pemphigus, erythroderma. Especially effective prednisolone ointment for skin diseases accompanied by weeping rashes and severe itching. Used prednisolone ointment and the full or partial loss of hair.

Treatment with ointment predneizolonovoy occasion in a period of not more than two weeks, but more often to remove the unpleasant phenomena such as tissue edema, and severe itching Moisture takes less time. Ointment applied thinly one to three times a day on the skin lesions. Babies prednisolone ointment is not recommended for more than a week in a row, we must not impose on the ointment warming and any other bandages.

Contraindications for appointment

Contraindications for topical prednisolone are hypersensitivity to the components of the patient prednisolone ointment, tuberculosis Tuberculosis - a full recovery is not guaranteed   skin, cutaneous manifestations of syphilis, viral infections (chickenpox, shingles Ringworm - not only infectious disease , Herpes infection is recurrent), a variety of skin rashes as a result of vaccination, pustular and fungal skin infections, skin tumors, breast-feeding Breastfeeding - a personal choice   feeding.

With caution and only when there are serious indications prednisolone ointment is used during pregnancy because it can enter the bloodstream, have systemic effects, including cross the placenta to the fetus.

Side effects

With prolonged use of prednisolone ointment is also possible appearance of the skin areas of increased body hair - is a consequence of the hormonal action of prednisolone or atrophy (reduction in volume - thinning and fragility of the skin) - a consequence of increased protein breakdown of skin cells.

The skin under the influence of prednisolone ointment can develop petechial hemorrhages, stretching (tearing of collagen fibers that are thinner under the influence of prednisolone) areas of increased pigmentation or, on the contrary, white areas (devoid of pigmentation) of the skin. It slows down the healing tissue on a background of prednisolone - a consequence of a violation of protein metabolism in the skin cells. It is very rare when using prednisolone ointment develop allergic reactions.

All side effects disappear after canceling prednizolonooy ointment.

Despite the fact that the prednisolone ointment acts mainly locally, it is possible and its systemic effects on the human body, so it is used only on prescription.

Galina Romanenko

Nizoral cream - for the treatment of fungal infections of the skin - is a broad-spectrum antifungal action and is active against most fungal infections of the skin and smooth the skin of the scalp.

How does Nizoral cream

Nizoral for external use produced in the form of a 2% cream (1 g of cream contains 20 mg ketoconazole), an active substance which is ketokenozol. Auxiliaries are propylene glycol, stearyl alcohol, cetyl alcohol, sorbitan stearate, polysorbate 60, polysorbate 80, isopropyl myristate, sodium sulfite, anhydrous, purified water.

For external use Nizoral is not absorbed into the blood and acts only locally. It wilts deeply into the skin and inhibits the activity of pathogenic fungi by inhibiting the formation of cell membranes required biologically active substances, which leads to suppression of vital functions for fungi.

Nizoral cream is effective in fungal infections of the skin such as trichophytosis, microsporia, jock itch, athlete's foot and toes, kondidoz skin. A feature of the cream is that it is perfectly relieves burning and itching before the appearance of the first signs of recovery.

Indications and contraindications

Nizoral cream is used only for the treatment of fungal infections of the skin. In chmsle it is used to treat fungal infections of the skin smooth, jock itch, athlete's hands and feet, skin candidiasis, tinea versicolor, seborrheic dermatitis caused by fungi that cause dandruff while Dandruff: where it comes from, and what to do   (Pitirosporum oval).

Do not use this Nizoral in case of hypersensitivity to the components of the cream. With careful use cream during pregnancy and nursing Breastfeeding - a personal choice   breast, as clinical trials data of patients have not been conducted. Do not use Nizoral cream for the treatment of fungal infections of view.

How to apply Nizoral cream

When smooth skin fungal infections (candidiasis skin ringworm smooth skin, jock itch Jock itch: fungal infection , Athlete's hands and feet, pityriasis versicolor) Cream Nizoral cream is applied once a day to the affected skin and the adjacent areas of healthy skin.

When seborrheic dermatitis Nizoral cream is applied to the affected areas of the scalp one - two times a day depending on the severity of the lesion. Standard courses of treatment of various fungal infections: tinea smooth skin - 3-4 weeks, chromophytosis Ringworm - not only infectious disease   - 2-3 weeks, the skin candidiasis - 2-3 weeks, jock itch - 2-4 weeks, athlete's foot - 4-6 weeks, seborrheic dermatitis - 2-4 weeks. After treatment of seborrheic dermatitis is supportive treatment: Nizoral cream is applied once or twice a week.

Treatment is continued until the complete disappearance of all signs of fungal infection and for several days after their disappearance. If within one month of the disease is not improving, you should specify the diagnosis of the disease.

Sometimes the treatment of fungal infections Nizoral cream is used in conjunction with topical corticosteroids (for severe itching, burning, swelling of the skin). In this case, to prevent withdrawal of corticosteroids should be continued application of topical corticosteroids in the morning and evening of Nizoral cream, and then gradually over a two to three weeks, discontinue use of corticosteroids.

Side effects

Side effects cream Nizoral manifested mainly in the form of burning and itching caused by skin irritation. Most often it is a sign you are hypersensitive to the components of the cream. Sometimes, there are signs of contact allergic dermatitis in the form of redness and swelling of the skin, the appearance on its surface bubbles with clear content. Allergic reactions may occur in the form of urticaria.

Is it possible to overdose?

The use Nizoral cream on very large areas of skin or applying it with a thick layer several times a day can result in an overdose. This is manifested in redness, swelling the skin, burning sensation and itching. All these symptoms usually disappear after cessation of application of the cream. If swallowed Nizoral cream special treatment is required.

Nizoral cream - is an effective antifungal drug broad spectrum of action. It is practically not absorbed into the bloodstream and therefore gives little side effects. However, a fungal infection should be treated only under medical supervision, since no laboratory control cure to get rid of these diseases is very difficult.

Galina Romanenko