Ointment prednisolone's anti-inflammatory and has a strong anti-allergic effect. But this greatly disturbed immune system of the skin, which promotes bacterial, fungal and viral infections. Therefore, prednisolone ointment is not shown at all skin diseases.
How does prednisolone ointment
Prednisolone is for external use is available in the form of 0, 5% ointment prednisolone (1 g of ointment contains 5 mg of prednisone).
Prednisolone ointment is fast and effective local anti-inflammatory, anti-allergic effect, relieves swelling of the skin and subcutaneous tissue, itchy skin. Prednisolone penetrates the skin cells and inhibits the synthesis of biologically aktivynyh them substances that promote the formation of inflammation and allergies.
Prednisolone ointment also suppresses the formation of skin cells of nucleic acids (including DNA) that suppresses the proliferation of skin cells, including cells of the connective tissue - it prevents the formation of rough scars on the skin, which may be a consequence of inflammation and wounds.
Prednisolone ointment antiallergic action associated with a reduced number of basophils in the peripheral blood and suppressing the formation and secretion of biologically active substances involved in the allergic process such as histamine.
Prednisolone ointment topically applied, however, it is well absorbed into the bloodstream and has a systemic action on the body.
Prednisolone - against inflammation, allergy and pain, but with complications
in the liver and then excreted through the gastrointestinal tract and kidneys. Prednisolone well penetrates through the placenta to the fetus and is excreted in human milk.
With which diseases and how changes in the prednisolone ointment
Prednisolone ointment, as well as other dosage forms of prednisolone, can only be used by a physician. Assign her skin diseases infectious origin, such as atopic dermatitis, atopic dermatitis, eczema is true, seborrheic dermatitis, psoriasis, pemphigus, erythroderma. Especially effective prednisolone ointment for skin diseases accompanied by weeping rashes and severe itching. Used prednisolone ointment and the full or partial loss of hair.
Treatment with ointment predneizolonovoy occasion in a period of not more than two weeks, but more often to remove the unpleasant phenomena such as tissue edema, and severe itching Moisture takes less time. Ointment applied thinly one to three times a day on the skin lesions. Babies prednisolone ointment is not recommended for more than a week in a row, we must not impose on the ointment warming and any other bandages.
Contraindications for appointment
Contraindications for topical prednisolone are hypersensitivity to the components of the patient prednisolone ointment, tuberculosis
Tuberculosis - a full recovery is not guaranteed
skin, cutaneous manifestations of syphilis, viral infections (chickenpox, shingles
Ringworm - not only infectious disease
, Herpes infection is recurrent), a variety of skin rashes as a result of vaccination, pustular and fungal skin infections, skin tumors, breast-feeding
Breastfeeding - a personal choice
With caution and only when there are serious indications prednisolone ointment is used during pregnancy because it can enter the bloodstream, have systemic effects, including cross the placenta to the fetus.
Prednisolone ointment usually well tolerated, but after prolonged use (more than two weeks in adults and in children over a week), it can cause a reduction in cutaneous immunity, which is fraught with additional bacterial, viral or fungal infection.
With prolonged use of prednisolone ointment is also possible appearance of the skin areas of increased body hair - is a consequence of the hormonal action of prednisolone or atrophy (reduction in volume - thinning and fragility of the skin) - a consequence of increased protein breakdown of skin cells.
The skin under the influence of prednisolone ointment can develop petechial hemorrhages, stretching (tearing of collagen fibers that are thinner under the influence of prednisolone) areas of increased pigmentation or, on the contrary, white areas (devoid of pigmentation) of the skin. It slows down the healing tissue on a background of prednisolone - a consequence of a violation of protein metabolism in the skin cells. It is very rare when using prednisolone ointment develop allergic reactions.
All side effects disappear after canceling prednizolonooy ointment.
Despite the fact that the prednisolone ointment acts mainly locally, it is possible and its systemic effects on the human body, so it is used only on prescription.