Augmentin - a combined broad-spectrum antibiotic, which includes semi-synthetic penicillin which can degrade enzymes produced by certain bacteria and clavulanic acid suppressing activity of these enzymes. As a result, augmentin has broad spectrum of activity and is resistant to the action of degrading enzymes antibiotic.

The mechanism of action augmentin

Augmentin - a combined antibiotic, which includes amoxycillin (semisynthetic penicillin wide action spectrum) and clavulanic acid. Produces Augmentin group of pharmaceutical companies GlaxoSmithKline (UK) as a powder for solution for injection in vials of powder for suspension in vials and oral tablets.

Other pharmaceutical companies on the basis of a combination of drugs amoxicillin and clavulanic acid sold under the name: amoklavin, amoklan, amoksiklav Amoxiclav - an effective tool against infections Amoxicillin and clavulanate potassium, sodium, Arlette, klavotsin, clavulanate, klamosar, chickens, liklav, medoklav, moksiklav, panklav, ranklav, rapiklav, flemoklav soljutab.

Part of the amoxicillin augmentin refers to a group of semisynthetic penicillins and has a broad spectrum of antibacterial action. Sensitivity to exhibit many infectious agents, including staphylococcus, streptococcus, E. coli, Proteus, Salmonella, agents of bacillary dysentery (Shigella), Proteus and others. But the greatest disadvantage of this formulation is that it is destroyed under the action of enzymes which produce some types of bacteria. These enzymes are called penicillinase or beta-lactamase.

In order to suppress the effect of beta-lactamase, amoxicillin clavulanic acid combined with - beta-lactam compound, inhibits the action of beta-lactamase. As a result, the combined drug Augmentin has a broad spectrum of antimicrobial activity, including with respect to infectious agents, having the capacity to secrete the enzyme penicillinase.

Indications and contraindications

Augmentin appointed following the treatment of infectious and inflammatory diseases caused by susceptible to infectious agents:

• upper respiratory tract and upper respiratory tract - purulent tonsillitis, pharyngitis, tonsillitis, inflammatory processes in the area of ​​the paranasal sinuses, middle ear infections;
• lower respiratory tract infections - acute and chronic bronchitis, pneumonia, pleurisy, bronchiectasis Bronchiectasis - when the work light under threat ;
• kidney and urinary tract infections - acute and chronic pyelonephritis and cystitis;
• genitals - acute and chronic inflammatory processes in the uterus and its appendages (including abortion and childbirth), prostatitis and sexually transmitted infections (eg, gonorrhea);
• skin and subcutaneous tissue - boils, carbuncles, abscesses, abscesses;
• bones and joints - acute and chronic arthritis, osteomyelitis;
• postoperative septic complications, as well as their prevention.

Contraindications for use of augmentin are:

• severe liver disease in violation of their functions;
• jaundice associated with the previous technique augmentin;
• Hypersensitivity to Augmentin and other antibiotics from the group of penicillins and cephalosporins.

Augmentin is used with caution during pregnancy and nursing Breastfeeding - a personal choice   feeding, as well as in kidney function (may reduce the daily dose).

Side effects

In most cases, Augmentin well tolerated, but there are side effects. Most often when taking augmentin develop allergic reactions such as hives, itchy skin rash, anaphylactic shock; rarely develop allergic processes such as Stevens-Johnson syndrome (severe skin and mucous membranes), and others. Regardless of the severity of allergic reactions need to stop the use of augmentin.

In addition, side effects are possible:

• the part of the digestive system - nausea, vomiting, diarrhea, and intestinal candidiasis of the mouth, inflammation of the walls of the large intestine, the liver, hepatitis Hepatitis - the scourge of our time Jaundice related to bile stasis;
• in the blood - a transient decrease in blood leukocyte count, red blood cells and platelets; reduction of blood clotting;
• the central nervous system - headache, dizziness, convulsive readiness, motor and mental stimulation;
• by the kidneys and urinary tract - interstitial nephritis (inflammation of the connective tissue in the area of ​​the foundations of the kidneys), the appearance of salt crystals in a lobe;
• local capacity development of thrombophlebitis at the site of intravenous administration.

Augmentin - a modern efficient and non-toxic antibiotic.

Galina Romanenko

  Many antibiotics, including dalatsin can cause an overgrowth of harmful bacteria in the colon. This can lead to various complications, from mild diarrhea to colitis - an inflammation of the colon, a potentially life-threatening. The likelihood that such dalatsin cause an infection is quite high, so it should be used only for the treatment of serious diseases that can not be treated with other antibiotics. Be sure to tell your doctor if you have ever had colitis or other disorders affecting the stomach or intestines.

These complications can develop even during treatment, or a few months after completing the course of treatment. Call your doctor if in a few months after receiving dalatsina you will have the following symptoms: watery stools or stools with traces of blood, diarrhea, stomach cramps, sudden increase in body temperature.

Why use dalatsin?

With dalatsina treat a variety of bacterial infections, including infections of the lungs, skin, blood, female reproductive organs, and many internal organs. Dalatsin relates to antibiotics Antibiotics - whether they will help you in the foreseeable future?   lincomycin group. It slows or interrupts the reproduction of bacteria. Antibiotics such as dalatsin not kill viruses that cause the common cold, flu and other infections.

Application

Dalatsin comes in the form of capsules and oral solution. Typically, it should be taken 3-4 times per day. The duration of treatment depends on the kind of infection that the patient is sick. Dalatsin recommended to take approximately the same time each day. Do not take more or less medication than your doctor has advised.

• Dalatsina solution must be properly shaken before each use.
• The capsules should be taken with a full glass of water to the drug did not cause throat irritation.
• You should feel an improvement within a few days after the start of dalatsina. If symptoms become less severe, or if you feel worsening, call your doctor.
• Although as soon as you feel better, go to the end of treatment. Otherwise, a relapse can occur; It is that bacteria become resistant to antibiotics and dalatsin be ineffective for you.
• With dalatsina also treat acne. In addition, it is used in combination with other medicines for the treatment of anthrax Anthrax - when to panic?   and malaria Malaria - these dangerous mosquitoes .
• Sometimes it is used for the treatment of patients with ear infections and toxoplasmosis Toxoplasmosis: pregnant women against cats   (an infection that can cause serious complications in people with weakened immune systems or unborn children whose mothers are infected), if these conditions can not be cured by other drugs.
• Dalatsin used to prevent endocarditis (infection of the heart valves), people belonging to risk groups.

Before taking dalatsin:

Tell your doctor if you have had an allergy to dalatsin, lincomycin and any other medications. If you take dalatsin capsules, tell your doctor about allergies to aspirin or tartrazine.

• Tell your doctor about all medications you are taking at this time
• Tell your doctor if you have a history of asthma, allergies, eczema, liver and kidney disease
• Also worth mentioning the doctor that you are pregnant, breastfeeding or planning to become pregnant
• Side effects:
• Sickness
• Vomiting
• Pain in the joints
• Pain when swallowing
• Heartburn
• Occurrence of white spots in the mouth
• Thick white vaginal discharge
• Burning, itching, or swelling in the vaginal area

When the following side effects you should immediately contact your doctor:

• Blisters on the skin
• Rash
• Difficulty breathing and swallowing
• The yellowish tinge to the skin and whites of the eyes