Nootropil - it is quite an effective drug, it is usually well tolerated, but, nevertheless, can not have contraindications and side effects. All indications and contraindications must take into account when assigning physician nootropil.

Contraindications and side effects nootropil

Contraindications and side effects nootropil arise from the mechanism of action of this drug. Nootropil two main effects - improvement of metabolic processes in the neurons of the brain by increasing energy and improving blood circulation in the brain due to the fact that inhibited blood coagulation and adhesion (adhesion) of red blood cells to the walls of blood vessels.

Nootropil is rapidly absorbed into the blood and then excreted unchanged in the urine by the kidneys.

Nootropil is usually well tolerated, but there may be side effects that occur primarily disorders of the central nervous system. This irritability Irritability - you try to control my temper , Anxiety, insomnia or drowsiness, dizziness, headaches, depression, often accompanied by anxiety Anxiety - how to distinguish normal from disease?   and increased motor activity. In children with perinatal brain lesions may appear anxiety, restlessness worsen, motor disinhibition. They become unbalanced, irritable. It nootropil affect the ability to drive vehicles, so when taking a car to drive is not recommended.

On the part of the gastrointestinal tract can cause nausea, vomiting, diarrhea, abdominal pain Abdominal pain: Types and Symptoms . In elderly patients may be more frequent angina Angina: When the heart needs help .

Contraindications for use in bleeding nootropil

Nootropil can not be used, as in the external and internal bleeding, as it lowers the rolling capacity of the blood by inhibiting the aggregation (bonding) platelets. Nootropil therefore it can not be applied immediately after the bleeding in the brain (hemorrhagic stroke). Later, in the recovery stage, nootropil used, but with caution.

Be wary appoint nootropil and bleeding disorders, with frequent prolonged bleeding (eg, cyclic uterine bleeding and atsiklichskih) if the patient will have surgery, and so on.

Contraindications with severe kidney disease

Nootropil excreted through the kidneys unchanged. In severe kidney disease, accompanied by significant impairment of their function, nootropil will linger in the body, which can significantly increase its side effects. Therefore, when kidney disease nootropil may be imposed only under the control of biochemical blood tests (creatinine clearance), and if the figures are not correct, reduce the dose nootropil.

In old age often lose their kidney function, so elderly patients nootropil administered with caution and under the supervision of laboratory tests.

Contraindications to certain categories of patients

Nootropil is not prescribed to pregnant women - it passes through the placenta to the fetus. The laboratory tests of the drug in animals have not revealed any adverse effects on the fetus, but the necessary clinical studies in pregnant women have not been conducted. Nootropil why pregnant women do not prescribe.

Nursing mothers also take nootropil contraindicated, since it is allocated to breast milk. Nootropil concentration in the blood of newborn reaches almost same concentration as in the blood of the mother. If necessary, use during lactation should refrain from breastfeeding.

If a woman nootropil is vital, it is recommended to interrupt breastfeeding. The reason also lies in the absence of clinical trials on children nootropil to a year - they also nootropil not assigned.

Who else is contraindicated nootropil

Nootropil can cause mood disorders and agitation, so it is not suitable for depression, accompanied by anxiety - agitated depression.

Contraindications nootropil Huntington's chorea - a chronic progressive hereditary degenerative diseases characterized by an increase of involuntary movements (hyperkinesias), and dementia. Nootropil can strengthen hyperkinesis.

Not applicable nootropil and in case of hypersensitivity to the drug.

Nootropil - effective and quite safe drug, but his appointment is required to take into account all the indications and contraindications.

Galina Romanenko

Afobazol - it's an easy day tranquilizer that has both anti-anxiety and light stimulating effect. This is not to afobazole formed psychic and physical dependence and after treatment with this drug there is no withdrawal. The drug has been applied in the treatment of anxiety disorders are mainly functional character.

The mechanism of action afobazole

Afobazol (active ingredient - morfolinoetiltioetoksibenzimidazola dihydrochloride) - a tranquilizer and anxiolytic - a substance that relieves anxiety mainly in the neuroses, without causing pronounced antipsychotic action. Afobazol produces domestic pharmaceutical company Pharmstandard in tablets of 10 mg.

Afobazole peculiarity is that it does not cause lethargy and sleepiness, in contrast, has a slight activating effect, thus removing anxiety. Therefore afobazol take the afternoon - it is considered day tranquilizer. It relieves anxiety, tension, irritability, weakness, feeling constantly impending danger, allows a person to gather strength and to adapt to the team.

The therapeutic effect is achieved within a week after treatment and the maximum effect - a month. After a month of treatment effect is maintained for a further one to two weeks.

Afobazol non-toxic, does not cause relaxation of skeletal muscles, it has no adverse effects on memory and concentration. This drug does not cause addiction and drug dependence.

Afobazol well relieves tension in the internal organs and the autonomic nervous system, so it is widely used in the complex therapy in various diseases of the cardiovascular system, respiratory system, gastrointestinal tract, and so on.

Afobazole peculiarity is that it does not enhance the effects of alcohol and some other psychotropic drugs Psychotropic drugs and their effect on the brain   (e.g., thiopental). But he may increase the effects of certain anticonvulsants (eg, carbamazepine) and tranquilizers (eg, diazepam).

Afobazol especially shown to take people with anxious-hypochondriac character traits, self-doubt, too emotional. After oral administration, the drug is distributed in organs with a strong circulation and excreted from the body in about half an hour.

Indications and Contraindications

Afobazol appointed the following diseases and conditions:

• under general anxiety disorders, neurasthenia, adjustment disorders in society;
• in various diseases of internal organs (asthma, chronic diseases of the gastrointestinal tract, cardiovascular system, including high blood pressure, cardiac arrhythmias), skin, cancer, and other diseases;
• insomnia caused increased anxiety Anxiety - how to distinguish normal from disease?   and the expectation of trouble;
• in the vegetative-vascular disorders in the brain;
• premenstrual syndrome - increased irritability Irritability - you try to control my temper   up to social maladjustment, before menstruation;
• the syndrome of hangover (withdrawal syndrome) in patients with chronic alcoholism, smoking and drug addiction.

Contraindications afobazole are:

• age 18 years;
• Pregnancy and breast-feeding Breastfeeding - a personal choice   breast;
• hypersensitivity to the drug.

Side effects

Side effects afobazole may occur only in the form of hypersensitivity to the drug, which can be both allergic and non-allergic in nature.

Overdose afobazole rare and can manifest as pronounced calming (sedative) action and drowsiness, but without pronounced relaxing effect on the skeletal muscles. If symptoms of overdose have to wash out the stomach and take a few pills of activated carbon. Assign also antidote - 20% of the caffeine-sodium benzoate as a subcutaneous injection.

How to take afobazol

Afobazol can be purchased over the counter without a prescription, but it is better if it is prescribed by a doctor after a preliminary examination.

Take afobazol inside half an hour after eating the tablet (10 mg) three times a day (30 mg daily). The standard course of treatment - from two weeks to a month. In some cases, prescription dosage and duration of the course afobazole increase (up to 60 mg per day, and up to three months).

Afobazol - non-toxic and non-addictive drug that activates and well relieves anxiety. It can be in the home medicine cabinet.

Galina Romanenko