Retinoic ointment - application for skin diseases and skin aging
January 8, 2014
Retinoic ointment - use it very effectively, but only when she is appointed with all the indications and contraindications, and the healing process is like under medical supervision. If you do not know all the nuances of the application of the ointment, the treatment can be quit a week later, when the first side effects. But the side effects may be different - some require immediate discontinuation of the drug, and the other - a break in treatment.
Retinoic ointment in the treatment of acne
Acne most often develops in adolescence on the background of hormonal changes. But sometimes the rash is persistent and adults. Usually, the cause of acne is the increased blood levels of male sex hormones androgens. This situation can arise not only boys but also girls.
Under the influence of androgens increases the secretion of sebum with a simultaneous change of its composition - the sebum becomes more viscous. It appears as increased maturation and flaking of the surface layers of the epithelium of the hair follicle mouths, which are located in the sebaceous glands.
All these changes lead to the fact that desquamated epithelial cells are mixed with a viscous sebum and dust covering the skin and form a dense gray-black cork plugging the mouth of the sebaceous glands - comedones. In tightly corked sebaceous glands begin to actively proliferate bacterial infection and ulcers occur - acne.
Today, for the treatment of acne, including heavy use of retinoids - drugs based on activated retinol - vitamin A
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. Retinoic ointment contains a retinoid isotretinoin and is used to treat mild and moderate forms of acne. In the treatment of severe forms of the disease are used for systemic effects of retinoids in the form of drugs for oral and rectal suppositories.
Retinoic ointment is applied twice a day with a thin layer on the skin for 1-1, 5 months. Such a long course of treatment allows retinoids actively influence on skin cells. They inhibit the excessive proliferation and exfoliation of skin cells, inhibit the excessive secretion of sebum and normalize its chemical composition. As a result, eliminated the cause of acne
Acne: facial trouble
and it gradually passes.
Retinoic ointment for the treatment of rosacea
Rosacea - a chronic skin disease characterized by the appearance of facial skin persistent redness and telangiectasias tuberosity - reticula or visible stars of the small blood vessels. Upon accession to the inflamed skin infection pustules appear on it.
The causes of rosacea are not fully understood. It is established that patients with rosacea have increased sensitivity to blood vessels of the face exposed to factors such as heat, ultraviolet light, and others.
Changes in the skin of rosacea are located in areas of the skin prone to seborrhea, but the quantitative change of the secretion of the sebaceous glands is observed. If the increased blood levels of androgens, changes the function of the sebaceous glands, which leads to a proliferation of the sebaceous glands (including connective tissue therein) that impairs blood and lymph - patients have characteristic facial swelling.
For the treatment of rosacea in the complex treatment applied 0, 05 and 0%, 1% retinoic ointment, which has anti-inflammatory, protivoseboreynoe action protects the skin cells against external influences, activates skin immunity.
Retinoic ointment in the treatment of perioral dermatitis
Perioral dermatitis - a chronic skin disease, with skin rash around the mouth, and sometimes (much more rarely) on the cheeks and around the eyes. The main cause of this disease is now considered reduction of skin immunity against the background of hormonal disorders
Hormonal disorders - oversupply and a lack of equally dangerous
Arising in adolescence. This opportunistic microflora living on the surface of the skin begins to become active, multiply and cause inflammation. Reduction of cutaneous immunity may occur during the application of hormonal ointments, inhalations glucocorticoid hormones (e.g., bronchial asthma).
Treatment of perioral dermatitis - a difficult task. Today, to address it as part of a treatment often used retinoids, including retinoic ointment. Application reretinoevoy ointment reduces inflammation and improves skin immunity, which allows to suppress chronic inflammation.
Features of the application of retinoic ointment
Retinoic ointment may give specific side effects that are able to recognize a doctor. Thus, after approximately one to two weeks after initiation of treatment may occur exacerbation of the disease, about which was appointed retinoic ointment. In this case, it is recommended to stop the treatment, wait, when it is reduced, and then continue treatment.
A completely different tactics should be the appearance of allergic rash during treatment with retinoic ointment
Retinoic ointment - help with acne and wrinkles
. In this case, the ointment overturned and never ever prescribed.
Nizoral - tablets for the treatment of fungal infections
August 16, 2013
Nizoral - tablets for oral administration have a systemic antifungal activity. This is an effective antifungal drug broad spectrum. Like most antifungal agents, it can have several side effects, however, considered to be relatively nontoxic drug.
How do Nizoral tablets
Active ingredient is ketoconazole Nizoral. Each tablet contains 200 mg of Nizoral ketoconazole. Excipients: corn starch, lactose monohydrate, polyvidone, microcrystalline cellulose, colloidal silicon dioxide, magnesium stearate. Once in the gastrointestinal tract, ketoconazole is rapidly absorbed into the bloodstream and distributed in the body. In large concentrations it accumulates in the skin and nails. Can cross the blood-brain barrier and into the brain, but in an amount sufficient to exert a therapeutic effect.
Once in the tissue affected by a fungal infection, Nizoral inhibit ergosterol biosynthesis in fungi and changes the composition of other lipid components in the fungal cell membrane, leading to death or suppression of their life. Thereafter, the drug is decomposed in the liver and excreted in the bile through the intestines or in the urine.
Nizoral active against fungi causing skin infections drozhzhevidnym fungi and yeast, including fungal genus Candida, and the fungi causing systemic fungal infections of the human body.
With which diseases and how to apply Tablets
Tablets Nizoral used in the treatment of fungal infections of the skin, scalp or mucous membranes caused by dermatophytes, fungi or yeasts. Nizoral tablets are used in cases where it is impossible to assign a local treatment because of the large area of the affected areas, a considerable depth of the lesion or the absence of the effect of the previously held local treatment, as well as for the treatment of patients resistant to other antifungal drugs for systemic use.
Nizoral is widely used for the treatment of Microsporum, Trichophyton, jock itch, athlete's hands and feet, multi-colored lichen, folliculitis fungal, chronic candidiasis of the mucous membranes (including oral thrush and genital organs), and skin candidiasis. Apply Nizoral tablets for the treatment of systemic fungal infections.
Take Nizoral tablets inside while eating - it contributes to a better absorption of the drug. Dose and duration of its use in a variety of fungal infections prescribed by a doctor. Treatment should be carried out continuously until the complete disappearance of symptoms and laboratory confirmation of cure. If treatment is not carried out according to the rules, possible relapse. But if there are side effects such as loss of appetite, nausea, vomiting, fatigue, jaundice staining of the skin and sclera, dark urine, pain in the right hypochondrium, it is necessary to interrupt treatment - it says Nizoral toxic effects on the liver.
Who should not take Nizoral
In the systemic effects of Nizoral like most antifungal drugs may cause a number of side effects, so it can not be used:
- acute and chronic liver disease;
- in enzymatic disorders - a lack of the enzyme lactase to digest the milk sugar (lactose) intolerance to lactose malabsorption in the intestines of glucose and galactose;
- simultaneously with drugs have toxic effects on the liver;
- simultaneously with drugs capable of causing cardiac arrhythmia (astemizole, bepridilom, halofantrine, disopyramide, cisapride, dofetilide, levatsetilmetadolom (levometadil), mizolastine, pimozide | quinidine, sertindole, terfenadine and domperidone);
- simultaneously with ergot alkaloids - dihydroergotamine, ergometrine, ergotamine, metilergometrina;
- concomitantly with nisoldipine, eplerenone, irinotecan, everolimus;
- under the age of three years;
- In case of hypersensitivity to the drug the patient.
Nizoral Be wary appoint patients with low acidity of the stomach, as this case, the absorption of the drug. Patients taking, drugs that reduce gastric acidity, it is necessary to take them no earlier than two hours after taking the pill Nizoral. Be wary appoint patients with Nizoral as adrenal insufficiency, or under stress
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And patients who abuse alcohol (while taking Nizoral with alcohol may occur disulfiramopodobnyh reaction - facial flushing, rash, swelling, nausea, headache, and so on).
In the systemic application of Nizoral may cause the following side effects: headache, dizziness, skin sensitivity, sleepiness or insomnia, anxiety
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, Transient increase in intracranial pressure. There may be decreased or increased appetite, nausea, vomiting, diarrhea or constipation, abdominal pain
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, Transient liver function abnormalities, photophobia, intolerance to alcohol, pain in muscles and joints, nosebleeds, lowering blood pressure when rising sharply.
Men may increase the breast, reducing the concentration of male sex hormones in the blood and sperm, erectile dysfunction
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. Occasionally found alopecia, skin rash, itching, dermatitis, reducing the number of platelets in the blood, adrenal insufficiency, and allergic reactions.