Fosfalyugel often used in the complex treatment of various diseases of the gastrointestinal tract. This drug is quite effective and safe, nevertheless, it has contraindications for receiving and prolonged uncontrolled use can produce side effects.
How does Aluminium phosphate gel
Fosfalyugel refers to drugs with antacid (neutralizes the effect of hydrochloric acid) effect. It is composed of active substance (aluminum phosphate) and adjuvants (sorbitol, agar, pectin, calcium sulfate dihydrate, potassium sorbate, etc.) that enhance and correct the action of aluminum phosphate.
Fosfalyugel features of action is that it is almost not absorbed into the blood and acts locally, mainly in the stomach. It quickly neutralizes hydrochloric acid, but not completely, but to a physiological level, whereupon the effect persists for several hours. The absence of a sharp decline in gastric acidity eliminates side effects such as stimulation of the secretion of hydrochloric acid, characteristic of some other antacids (such as baking soda).
Fosfalyugel also has a protective effect - it protects the mucosa of the upper gastrointestinal tract from harmful influences, covering it with a protective film. At the same time, and it has a slight anesthetic effect, thereby reducing the dosage of other painkillers.
Finally, Aluminium phosphate gel is the adsorbent. This means that it is deposited on the surface and excrete toxic substances, including products resulting from improper digestion, allergens, toxins from food, drugs and so forth.
It is thought that Aluminium phosphate gel is one of the safest drugs in the group of antacids, so it can be purchased in pharmacies without a prescription. However, and this drug has side-effects, and hence contraindications for use.
The instructions to the drug, developed by the manufacturer (the Dutch pharmaceutical company Astellas Pharma Europe BV), indicated only one side effect of this drug - constipation. Constipation usually occurs on the background of the prolonged use of Fosfalyugel, as well as the appointment of his elderly patients. Manufacturers indicate that in such cases the patients will use a large amount of liquid. But it will not always as constipation can cause a large amount of aluminum in the intestine, which inhibits motor activity (peristalsis) of the body. In addition, in patients receiving Fosfalyugel may experience side effects such as nausea
Nausea - there may be problems with the nervous system
, Vomiting and changes in taste sensations.
Despite the fact that the Aluminium phosphate gel available over the counter without a prescription, a manufacturer warned that its long-term uncontrolled use can have consequences. This risk is increased in renal impairment and liver, and in severe cardiovascular diseases.
From laboratory indicators of long-term use Fosfalyugel
Fosfalyugel - a cure for heartburn, belching and stomach pains
high dose levels can reduce the content of phosphorus and calcium, increase of aluminum content.
Especially dangerous is the increase in the concentration of aluminum in the blood. Penetrating into the brain cells, aluminum can cause them to metabolic disorders. Thus, there is a risk of exchange-dystrophic processes in the brain tissue. This state has been called encephalopathy. That is why the Aluminium phosphate gel should not be taken in patients with disorders of the central nervous system.
The decrease in blood calcium and increased release of his urine is also dangerous. Calcium salts may contribute to the formation of stones in the urinary system that will eventually lead to a decrease in kidney function. Furthermore, the lack of calcium in the blood will cause its elution from the bone, which can lead to brittle fractures and bone (osteoporosis).
Fosfalyugel can not be used in case of hypersensitivity to its components from the patient's body, with severe renal impairment, and Alzheimer's disease
Alzheimer's disease - can be slowed down, it can not be cured
(intellectual disabilities associated with metabolic processes in the brain).
Precautions Aluminium phosphate gel to be applied in reducing the liver and severe diseases of the cardiovascular system.
Fosfalyugel - is an effective and safe drug, if used by a physician or occasionally to settle heartburn
Heartburn - no cause for concern?