Fosfalyugel often used in the complex treatment of various diseases of the gastrointestinal tract. This drug is quite effective and safe, nevertheless, it has contraindications for receiving and prolonged uncontrolled use can produce side effects.

How does Aluminium phosphate gel

Fosfalyugel refers to drugs with antacid (neutralizes the effect of hydrochloric acid) effect. It is composed of active substance (aluminum phosphate) and adjuvants (sorbitol, agar, pectin, calcium sulfate dihydrate, potassium sorbate, etc.) that enhance and correct the action of aluminum phosphate.

Fosfalyugel features of action is that it is almost not absorbed into the blood and acts locally, mainly in the stomach. It quickly neutralizes hydrochloric acid, but not completely, but to a physiological level, whereupon the effect persists for several hours. The absence of a sharp decline in gastric acidity eliminates side effects such as stimulation of the secretion of hydrochloric acid, characteristic of some other antacids (such as baking soda).

Fosfalyugel also has a protective effect - it protects the mucosa of the upper gastrointestinal tract from harmful influences, covering it with a protective film. At the same time, and it has a slight anesthetic effect, thereby reducing the dosage of other painkillers.

Finally, Aluminium phosphate gel is the adsorbent. This means that it is deposited on the surface and excrete toxic substances, including products resulting from improper digestion, allergens, toxins from food, drugs and so forth.

It is thought that Aluminium phosphate gel is one of the safest drugs in the group of antacids, so it can be purchased in pharmacies without a prescription. However, and this drug has side-effects, and hence contraindications for use.

Side effects

The instructions to the drug, developed by the manufacturer (the Dutch pharmaceutical company Astellas Pharma Europe BV), indicated only one side effect of this drug - constipation. Constipation usually occurs on the background of the prolonged use of Fosfalyugel, as well as the appointment of his elderly patients. Manufacturers indicate that in such cases the patients will use a large amount of liquid. But it will not always as constipation can cause a large amount of aluminum in the intestine, which inhibits motor activity (peristalsis) of the body. In addition, in patients receiving Fosfalyugel may experience side effects such as nausea Nausea - there may be problems with the nervous system , Vomiting and changes in taste sensations.

Despite the fact that the Aluminium phosphate gel available over the counter without a prescription, a manufacturer warned that its long-term uncontrolled use can have consequences. This risk is increased in renal impairment and liver, and in severe cardiovascular diseases.

From laboratory indicators of long-term use Fosfalyugel Fosfalyugel - a cure for heartburn, belching and stomach pains   high dose levels can reduce the content of phosphorus and calcium, increase of aluminum content.

Especially dangerous is the increase in the concentration of aluminum in the blood. Penetrating into the brain cells, aluminum can cause them to metabolic disorders. Thus, there is a risk of exchange-dystrophic processes in the brain tissue. This state has been called encephalopathy. That is why the Aluminium phosphate gel should not be taken in patients with disorders of the central nervous system.

The decrease in blood calcium and increased release of his urine is also dangerous. Calcium salts may contribute to the formation of stones in the urinary system that will eventually lead to a decrease in kidney function. Furthermore, the lack of calcium in the blood will cause its elution from the bone, which can lead to brittle fractures and bone (osteoporosis).

Contraindications

Fosfalyugel can not be used in case of hypersensitivity to its components from the patient's body, with severe renal impairment, and Alzheimer's disease Alzheimer's disease - can be slowed down, it can not be cured   (intellectual disabilities associated with metabolic processes in the brain).

Precautions Aluminium phosphate gel to be applied in reducing the liver and severe diseases of the cardiovascular system.

Fosfalyugel - is an effective and safe drug, if used by a physician or occasionally to settle heartburn Heartburn - no cause for concern? .

Galina Romanenko

Indications for use of ranitidine are all diseases of the digestive system, one way or another associated with increased secretion of gastric juice and its high acidity. This not only diseases of the stomach, but also diseases of esophagus, duodenum, small bowel initial pancreas Diabetes and pancreas - the things you need to know .

The use of ranitidine in the treatment of diseases of the stomach

Ranitidine is used to treat chronic gastritis with increased secretion of gastric juice and gastric ulcer. Exposure to high acidity of gastric juice can have a devastating effect on the wall of the stomach, especially if there is already ulcerative process. Violation of the integrity of the stomach wall is fraught with serious complications such as gastric bleeding (occurs when the destruction of the walls of blood vessels feeding the stomach), and perforation of the stomach and the subsequent development of the inflammatory process in the abdominal cavity (peritonitis).

Since ranitidine able to significantly and permanently suppress gastric acid secretion and acidity, it is used as a treatment aggravation of these diseases as well as for their prophylaxis.

Apply ranitidine well as violations of the stomach wall caused by stress, nesterodnyh taking anti-inflammatory drugs (eg, aspirin).

In the treatment of exacerbations of chronic gastritis Gastritis - several stomach disorders   and peptic ulcer ranitidine 150 mg administered twice daily or 300 mg at night regardless of the meal. The course of treatment - 1-2 months. For prevention enough 1 tablet (150 or 300 mg on prescription) overnight. The duration of prophylactic individual. Film-coated tablets, not chewed with a little water. Effervescent tablets completely dissolve in a glass of water and then drink.

Quenched treatment ranitidine Ranitidine - help in the prevention of relapse of peptic ulcer   It is not recommended, since it is possible aggravation of peptic ulcer disease.

The use of ranitidine in the treatment of diseases of the esophagus

Diseases of the esophagus is usually closely associated with diseases of the stomach. Thus, reflux oesophagitis occurs under constant contact with acidic gastric juice into the esophagus. As a rule, in this case reveals the failure of the sphincter (a circular muscle that compresses and decompresses) between the esophagus and the stomach. As a result, the esophageal wall are destroyed with the formation of ulcers, ulcers (small and large abscesses and phlegmons), which may lead to a complete perforation of the esophagus.

Patients with reflux esophagitis experiencing great suffering. At the beginning of the disease - it is a constant heartburn, then join exhausting patient pain along the esophagus. This leads to sleep disorders Dreams: how to understand our dreams , Neuroses. Appointment of ranitidine reduces heartburn and relieves pain. It helps to restore the status of the esophageal mucosa. Ranitidine in reflux esophagitis assigned 150 mg twice a day (morning and evening) or 300 mg at night. In severe disease, constant heartburn and pain the dose can be increased to 150 mg four times a day. The course of treatment usually lasts for 2-3 months.

The use of ranitidine in the treatment of diseases of other digestive organs

Ranitidine is used at duodenal ulcer as well as gastric ulcer.

In some cases, benign tumors (adenomas) pancreas can significantly stimulate the secretion of gastric juice and acidity. This happens because such tumors produce the hormone gastrin, and he in turn stimulates the secretion of gastric juice and hydrochloric acid. This process is often ulcerative does not extend to the stomach, and duodenum and jejunum, and can carry a common character. This disease has been called Zollinger-Ellison syndrome, it is difficult to treat, and gives patients with severe pain.

Ranitidine can significantly alleviate the condition of these patients and to stop the spread of ulcer process. It is administered initially at 150 mg three times a day, but if necessary, the dose may be increased. To prevent bleeding from the gastrointestinal tract ranitidine 150 mg administered twice a day. The duration of treatment and prevention of individual, prescribed by a doctor.

Is it possible to overdose?

Yes, maybe that's why ranitidine, especially in high doses, should appoint a doctor monitoring the patient's condition. In case of overdose may cause convulsions, cardiac disorders, and hallucinations. In this case, it is recommended to call an ambulance. If it is taken ranitidine tablets, prior to arrival of an ambulance you can wash out the stomach.

Galina Romanenko