A disease in which there is overgrowth of tissue in a limited area, always requires observation and exclusion of cancer. It is in this disease is focal hyperplasia of the endometrium of the uterus, which apparently substitutes one or more polyps.
Why start focal hyperplasia of the endometrium
Hormonal support menstrual always lead to changes in the uterine cavity. Thus, the secretion of follicle large amounts of estrogen leads to the fact that the mature egg is retained in the ovary, as for its release (ovulation) need the hormones of the second half of the menstrual cycle (luteinizing hormone, the pituitary gland and the female sex hormone progesterone), but not enough, which leads to long-term the first phase of the menstrual cycle, lack of ovulation
Ovulation - How to determine as accurately as possible?
and the widening of the mucous membrane of the uterus. With the onset of the second phase with a lack of progesterone
Progesterone - norm and pathology
pachymenia hardly reduced in volume and then, by the end of the menstrual cycle is rejected, usually with severe bleeding. Thus the walls of the uterine cavity may be residual mucosa that will support intermenstrual bleeding period and then become the basis of focal overgrowth of tissue, and possibly in the formation of uterine polyps.
Maybe another "scenario": estrogen produced little, and as the egg is not matured, produced them is long, wavy, with the result that the egg never ripens not released from the ovary and menstrual bleeding continues long, wavy. Bleeding is not too strong, but eventually loses blood a lot. In this case, the mucous membrane of the uterus is gradually torn away and some of its parts can not be removed.
Such non-remote areas of mucous membrane lesions may be initially proliferating mucosa and then form the basis for polyps, which can be glandular, fibrous or adenomatous (benign tumor of glandular tissue). The thickness of the mucous membrane of the uterus (the endometrium) at focal hyperplasia can reach 5-6 cm.
Contribute to the formation of polyps, inflammatory diseases of the uterus, injuries (including severe birth abortion), endocrine disorders, including those of a general nature (diabetes, thyroid disease
Thyroid disease - women at risk
, Obesity, etc.), stress, genetic predisposition and so on.
Focal may be atypical endometrial hyperplasia, in which tissue cells change their appearance. This kind of focal hyperplasia often turns into a malignant tumor.
How does the uterus at the focal endometrial hyperplasia
Polyps of the glandular or glandular-fibrous tissue typically have a rounded body or slightly elongated shape and leg. Polyp growths formed by all layers of the mucous membrane of the uterus along with the underlying tissue. Its base is made up of fibrous and glandular cells. A polyp can be one, several, or multiple polyps are found. In most polyps located in the upper part of the uterus (the bottom) and in the place where the body of the uterus fallopian tubes depart.
Top polyps are smooth, pink surface. But in some cases, the polyp is ulcerated because of circulatory disorders, which always accompany cyclical rejection of the endometrium. Under the microscope, it is seen that in the polyp tissue includes cancer of various sizes, partially penetrating into the middle muscular layer of the uterus. In addition, it has many components of connective tissue and blood vessels dilated sclerosed.
Focal atypical endometrial hyperplasia is a hotbed of altered mucosal tissue in which there are cells with more or less severe atypia. When these foci appear in the polyp, a polyp called adenomatous.
Diagnosis and treatment
Diagnosis can be made based on the typical occurrences of the disease (cyclic and acyclic heavy or prolonged bleeding), as well as additional testing. We investigate the hormonal status of blood occasion ultrasound of the pelvic organs and the uterus using a vaginal probe, endoscopy (hysteroscopy) with taking a piece of tissue for analysis, X-ray examination of the uterus (hysterography), if necessary, the radioisotope research and cancer.
Lobular hyperplasia, including polyps removed by scraping the uterine cavity in the process of therapeutic hysteroscopy. While the patient is on the operating table, conducted histological examination of the removed tissue. Upon detection of atypical cells specific to a malignant tumor, the uterus was removed.
After surgery, curettage of the uterus
Curettage - how dangerous it is?
woman appointed hormonal therapy, which aims - preventing proliferation (proliferation) of the mucous membrane of the uterus.