Contraindications for use betaserk there, but many of them, as an active substance of this drug is a synthetic analogue of histamine - a substance present in all cells and tissues. However, take into account contraindications when appointing betaserk necessary.
Features betaserk action on the human body
Active ingredient betaserk
Betaserk - a drug that helps restore the balance
betahistine is - a synthetic analogue of histamine. Histamine - a substance that serves multiple functions in the body. It is involved in the regulation of vital functions of the organism and plays an important role in the development of a number of disease states.
Histamine is found in large quantities in the inactive bound form in various organs and tissues of animals and humans. Histamine is released during inflammation and allergic reactions. The release of histamine from a bound state in allergic reactions is characteristic reactions such as redness and swelling of the skin, itching, burning, blistering. A certain amount of histamine contained in the brain, where it acts as a neurotransmitter (facilitates the transmission of nervous excitement from neuron to).
In the body, there are three types of specific histamine receptors - N1-, H2 and H3 receptors. Under the action of histamine H1- receptors to dilate the capillaries, liquid part of blood into the surrounding tissue propotevaet appear edema, narrowed bronchi. When exposed to histamine H2 - receptors is an increase in gastric acid secretion.
When exposed to the histamine H3 - receptors located in the central and peripheral nervous system, is suppressed release of neurotransmitters (GABA, acetylcholine, serotonin, norepinephrine).
Similarly, histamine acts and betaserk he gently stimulates the activity of the H1 - histamine receptors, thus activating the capillary blood circulation (including in the form of the inner ear). At the same time it inhibits the activity of the H3 receptor, which leads to suppression of such manifestations as dizziness
Dizziness - if the ground is slipping from under his feet
and poor coordination. This allows you to apply betaserk in the pathology of the inner ear - violation of balance and hearing.
Betaserk have few side effects and are usually at lower doses they disappear. In most cases, when taking this drug are side effects from the gastrointestinal tract - nausea, vomiting, sometimes, excessive flatulence, abdominal pain Moderate
Abdominal pain: Types and Symptoms
Sometimes there is a side effect of the central nervous system (the brain) in the form of headache.
Quite often when taking betaserk develop allergic reactions. They appear in the form of urticaria with the transition to angioedema, various types of allergic itchy rash. In very rare cases, anaphylactic shock. If you suspect an allergy reception betaserk should be discontinued.
This is contraindicated betaserk
To apply betaserk few contraindications. The main contraindication for receiving it is the presence of the patient pheochromocytomas - tumors of the adrenal medulla, actively producing hormones such as adrenaline and noradrenaline. Under the influence of these hormones in patients periodically develop crises with increased blood pressure, nausea, vomiting, palpitations, panic attacks, and so on. If a patient with pheochromocytoma enter histamine, it can provoke an attack. And as the active substance betaserk (betahistine) acts like histamine, assign it to patients with pheochromocytoma is impossible.
It is not necessary to apply betaserk as during acute gastric ulcer and duodenal ulcers, as a synthetic analogue of histamine can stimulate gastric acid secretion and increase canker wall of the gastrointestinal tract.
Contraindications reception betaserk are hypersensitive to the components of the drug by the body of the patient.
There are also contraindications for receiving betaserk associated not with identified side effects, and the absence of clinical trials on selected patient population. Thus betaserk not recommended during pregnancy, despite the fact that laboratory animal tests showed no negative impact of the drug to the fetus. It is also unknown whether betaserk allocated with breast milk, so it is not recommended for use during feeding baby
Breastfeeding - a personal choice
feeding. Not conducted clinical trials on children, so the drug is not used to treat children and adolescents up to 18 years.
The caution is recommended to appoint betaserk patients with gastric ulcer and duodenal ulcers, even without exacerbation.
Betaserk - effective and relatively safe drug, but it should be used only on prescription.